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O2.- [extracellular region]
Stable Identifier
R-ALL-3299686
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
SO2.-, superoxide
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Dictyostelium discoideum
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Cytoprotection by HMOX1 (Bos taurus)
BIL:ALB scavenges O2.- (Bos taurus)
O2.- [extracellular region]
Detoxification of Reactive Oxygen Species (Bos taurus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Bos taurus)
O2.- [extracellular region]
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
NADPH oxidase 2 generates superoxide from oxygen (Bos taurus)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate NADPH Oxidases (Bos taurus)
NADPH oxidase 2 generates superoxide from oxygen (Bos taurus)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)
O2.- [extracellular region]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Cytoprotection by HMOX1 (Canis familiaris)
BIL:ALB scavenges O2.- (Canis familiaris)
O2.- [extracellular region]
Detoxification of Reactive Oxygen Species (Canis familiaris)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Canis familiaris)
O2.- [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
NADPH oxidase 2 generates superoxide from oxygen (Canis familiaris)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate NADPH Oxidases (Canis familiaris)
NADPH oxidase 2 generates superoxide from oxygen (Canis familiaris)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Canis familiaris)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Canis familiaris)
O2.- [extracellular region]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Detoxification of Reactive Oxygen Species (Danio rerio)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Danio rerio)
O2.- [extracellular region]
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases Activate NADPH Oxidases (Danio rerio)
NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Danio rerio)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Danio rerio)
O2.- [extracellular region]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to chemical stress (Dictyostelium discoideum)
Detoxification of Reactive Oxygen Species (Dictyostelium discoideum)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Dictyostelium discoideum)
O2.- [extracellular region]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Cytoprotection by HMOX1 (Gallus gallus)
BIL:ALB scavenges O2.- (Gallus gallus)
O2.- [extracellular region]
Detoxification of Reactive Oxygen Species (Gallus gallus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Gallus gallus)
O2.- [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases Activate NADPH Oxidases (Gallus gallus)
NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Gallus gallus)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Gallus gallus)
O2.- [extracellular region]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
BIL:ALB scavenges O2.- (Homo sapiens)
O2.- [extracellular region]
Detoxification of Reactive Oxygen Species (Homo sapiens)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Homo sapiens)
O2.- [extracellular region]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Killing mechanisms (Homo sapiens)
WNT5:FZD7-mediated leishmania damping (Homo sapiens)
NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen (Homo sapiens)
O2.- [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
NADPH oxidase 2 generates superoxide from oxygen (Homo sapiens)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate NADPH Oxidases (Homo sapiens)
NADPH oxidase 2 generates superoxide from oxygen (Homo sapiens)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Homo sapiens)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Homo sapiens)
O2.- [extracellular region]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Cytoprotection by HMOX1 (Mus musculus)
BIL:ALB scavenges O2.- (Mus musculus)
O2.- [extracellular region]
Detoxification of Reactive Oxygen Species (Mus musculus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Mus musculus)
O2.- [extracellular region]
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
NADPH oxidase 2 generates superoxide from oxygen (Mus musculus)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate NADPH Oxidases (Mus musculus)
NADPH oxidase 2 generates superoxide from oxygen (Mus musculus)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Mus musculus)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Mus musculus)
O2.- [extracellular region]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Cytoprotection by HMOX1 (Rattus norvegicus)
BIL:ALB scavenges O2.- (Rattus norvegicus)
O2.- [extracellular region]
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Rattus norvegicus)
O2.- [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
NADPH oxidase 2 generates superoxide from oxygen (Rattus norvegicus)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases Activate NADPH Oxidases (Rattus norvegicus)
NADPH oxidase 2 generates superoxide from oxygen (Rattus norvegicus)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Rattus norvegicus)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Rattus norvegicus)
O2.- [extracellular region]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
Detoxification of Reactive Oxygen Species (Saccharomyces cerevisiae)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Saccharomyces cerevisiae)
O2.- [extracellular region]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to chemical stress (Schizosaccharomyces pombe)
Detoxification of Reactive Oxygen Species (Schizosaccharomyces pombe)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Schizosaccharomyces pombe)
O2.- [extracellular region]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Cytoprotection by HMOX1 (Sus scrofa)
BIL:ALB scavenges O2.- (Sus scrofa)
O2.- [extracellular region]
Detoxification of Reactive Oxygen Species (Sus scrofa)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Sus scrofa)
O2.- [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
NADPH oxidase 2 generates superoxide from oxygen (Sus scrofa)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases Activate NADPH Oxidases (Sus scrofa)
NADPH oxidase 2 generates superoxide from oxygen (Sus scrofa)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Sus scrofa)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Sus scrofa)
O2.- [extracellular region]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Cytoprotection by HMOX1 (Xenopus tropicalis)
BIL:ALB scavenges O2.- (Xenopus tropicalis)
O2.- [extracellular region]
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Xenopus tropicalis)
O2.- [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
NADPH oxidase 2 generates superoxide from oxygen (Xenopus tropicalis)
O2.- [extracellular region]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase Effectors (Xenopus tropicalis)
RHO GTPases Activate NADPH Oxidases (Xenopus tropicalis)
NADPH oxidase 2 generates superoxide from oxygen (Xenopus tropicalis)
O2.- [extracellular region]
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Xenopus tropicalis)
O2.- [extracellular region]
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Xenopus tropicalis)
O2.- [extracellular region]
External Reference Information
External Reference
superoxide [ChEBI:18421]
Participates
as an input of
BIL:ALB scavenges O2.- (Gallus gallus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Homo sapiens)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Mus musculus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Rattus norvegicus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Canis familiaris)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Bos taurus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Sus scrofa)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Danio rerio)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Xenopus tropicalis)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Gallus gallus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Dictyostelium discoideum)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Schizosaccharomyces pombe)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Saccharomyces cerevisiae)
BIL:ALB scavenges O2.- (Homo sapiens)
BIL:ALB scavenges O2.- (Mus musculus)
BIL:ALB scavenges O2.- (Rattus norvegicus)
BIL:ALB scavenges O2.- (Canis familiaris)
BIL:ALB scavenges O2.- (Bos taurus)
BIL:ALB scavenges O2.- (Sus scrofa)
BIL:ALB scavenges O2.- (Xenopus tropicalis)
as an output of
NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen (Homo sapiens)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Homo sapiens)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Mus musculus)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Rattus norvegicus)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Canis familiaris)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Sus scrofa)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Danio rerio)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Xenopus tropicalis)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Gallus gallus)
NADPH oxidase 2 generates superoxide from oxygen (Homo sapiens)
NADPH oxidase 2 generates superoxide from oxygen (Mus musculus)
NADPH oxidase 2 generates superoxide from oxygen (Rattus norvegicus)
NADPH oxidase 2 generates superoxide from oxygen (Canis familiaris)
NADPH oxidase 2 generates superoxide from oxygen (Bos taurus)
NADPH oxidase 2 generates superoxide from oxygen (Sus scrofa)
NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)
NADPH oxidase 2 generates superoxide from oxygen (Xenopus tropicalis)
NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Homo sapiens)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Mus musculus)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Rattus norvegicus)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Canis familiaris)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Sus scrofa)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Danio rerio)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Xenopus tropicalis)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Gallus gallus)
Other forms of this molecule
O2.- [phagolysosome]
O2- [cytoplasm]
O2.- [phagocytic vesicle lumen]
O2- [mitochondrial intermembrane space]
O2.- [mitochondrial matrix]
O2.- [cytosol]
Cross References
COMPOUND
C00704
HMDB Metabolite
HMDB0002168
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![O2.- [extracellular region] icon](/icon/R-ICO-013414.svg){kind=icon}
