NADPH oxidase 2 generates superoxide from oxygen

Stable Identifier
R-HSA-5218841
Type
Reaction
Species
Homo sapiens
Compartment
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The activated NOX2 complex generates superoxide (O2.-) by transferring an electron from NADPH in the cytosol to oxygen on the luminal or extracellular space (Bedard & Krause 2007).

Literature References
PubMed ID Title Journal Year
17237347 The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

Bedard, K, Krause, KH

Physiol. Rev. 2007
Participants
Participates
Catalyst Activity

superoxide-generating NAD(P)H oxidase activity of NOX2 complex:RAC1:GTP [plasma membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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