SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)

Stable Identifier
R-HSA-3299682
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
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SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)
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Extracellular Cu-Zn superoxide dismutase (SOD3) catalyzes the reaction of two molecules of superoxide (O2.-) to form one molecule of oxygen (O2) and one molecule of hydrogen peroxide (H2O2) (Marklund et al. 1982, Marklund 1982)

Literature References
PubMed ID Title Journal Year
7172448 Superoxide dismutase in extracellular fluids

Marklund, SL, Holme, E, Hellner, L

Clin. Chim. Acta 1982
6961438 Human copper-containing superoxide dismutase of high molecular weight

Marklund, SL

Proc. Natl. Acad. Sci. U.S.A. 1982
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
superoxide dismutase activity of SOD3 tetramer [extracellular region]
Physical Entity
SOD3 tetramer [extracellular region]
Activity
superoxide dismutase activity (0004784)
Orthologous Events
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Bos taurus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Caenorhabditis elegans)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Canis familiaris)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Danio rerio)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Dictyostelium discoideum)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Drosophila melanogaster)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Gallus gallus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Mus musculus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Rattus norvegicus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Saccharomyces cerevisiae)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Schizosaccharomyces pombe)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Sus scrofa)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Xenopus tropicalis)
Cross References
Rhea
Authored
May, B  (2013-04-20)
Reviewed
Kavdia, M  (2013-11-01)
Created
May, B  (2013-04-20)