SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)

Stable Identifier
R-HSA-3299682
Type
Reaction
Species
Homo sapiens
Compartment
extracellular region
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SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)
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Extracellular Cu-Zn superoxide dismutase (SOD3) catalyzes the reaction of two molecules of superoxide (O2.-) to form one molecule of oxygen (O2) and one molecule of hydrogen peroxide (H2O2) (Marklund et al. 1982, Marklund 1982)

Literature References
PubMed ID Title Journal Year
6961438 Human copper-containing superoxide dismutase of high molecular weight

Marklund, SL

Proc. Natl. Acad. Sci. U.S.A. 1982
7172448 Superoxide dismutase in extracellular fluids

Holme, E, Marklund, SL, Hellner, L

Clin. Chim. Acta 1982
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Catalyst Activity

superoxide dismutase activity of SOD3 tetramer [extracellular region]

Physical Entity
SOD3 tetramer [extracellular region] (Homo sapiens)
Activity
superoxide dismutase activity (GO:0004784)
Orthologous Events
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Bos taurus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Caenorhabditis elegans)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Canis familiaris)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Danio rerio)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Dictyostelium discoideum)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Drosophila melanogaster)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Gallus gallus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Mus musculus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Rattus norvegicus)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Saccharomyces cerevisiae)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Schizosaccharomyces pombe)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Sus scrofa)
SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Xenopus tropicalis)
Cross References
Rhea
Authored
May, B  (2013-04-20)
Reviewed
Kavdia, M  (2013-11-01)
Created
May, B  (2013-04-20)
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