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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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Data Schema
Reactome Research Spotlight
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Docs
Userguide
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How do I search ?
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CHOL [transport vesicle membrane]
Stable Identifier
R-ALL-216762
Type
Chemical Compound [SimpleEntity]
Compartment
transport vesicle membrane
Synonyms
cholesterol
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Bos taurus)
CHOL [transport vesicle membrane]
Transport of small molecules (Bos taurus)
ABC-family proteins mediated transport (Bos taurus)
ABC transporters in lipid homeostasis (Bos taurus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Bos taurus)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Bos taurus)
Plasma lipoprotein assembly (Bos taurus)
HDL assembly (Bos taurus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Bos taurus)
CHOL [transport vesicle membrane]
Plasma lipoprotein clearance (Bos taurus)
LDL clearance (Bos taurus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Bos taurus)
CHOL [transport vesicle membrane]
NCEH1 hydrolyzes cholesterol esters (Bos taurus)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Bos taurus)
HDL remodeling (Bos taurus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Bos taurus)
CHOL [transport vesicle membrane]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Caenorhabditis elegans)
CHOL [transport vesicle membrane]
Transport of small molecules (Caenorhabditis elegans)
Plasma lipoprotein assembly, remodeling, and clearance (Caenorhabditis elegans)
Plasma lipoprotein clearance (Caenorhabditis elegans)
LDL clearance (Caenorhabditis elegans)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Caenorhabditis elegans)
CHOL [transport vesicle membrane]
NCEH1 hydrolyzes cholesterol esters (Caenorhabditis elegans)
CHOL [transport vesicle membrane]
Transport of small molecules (Canis familiaris)
ABC-family proteins mediated transport (Canis familiaris)
ABC transporters in lipid homeostasis (Canis familiaris)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Canis familiaris)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Canis familiaris)
Plasma lipoprotein assembly (Canis familiaris)
HDL assembly (Canis familiaris)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Canis familiaris)
CHOL [transport vesicle membrane]
Plasma lipoprotein clearance (Canis familiaris)
LDL clearance (Canis familiaris)
NCEH1 hydrolyzes cholesterol esters (Canis familiaris)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Canis familiaris)
HDL remodeling (Canis familiaris)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Canis familiaris)
CHOL [transport vesicle membrane]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Danio rerio)
CHOL [transport vesicle membrane]
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
ABC transporters in lipid homeostasis (Danio rerio)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Danio rerio)
Plasma lipoprotein assembly (Danio rerio)
HDL assembly (Danio rerio)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Danio rerio)
CHOL [transport vesicle membrane]
Plasma lipoprotein clearance (Danio rerio)
LDL clearance (Danio rerio)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Danio rerio)
CHOL [transport vesicle membrane]
NCEH1 hydrolyzes cholesterol esters (Danio rerio)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Danio rerio)
HDL remodeling (Danio rerio)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)
CHOL [transport vesicle membrane]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Dictyostelium discoideum)
CHOL [transport vesicle membrane]
Transport of small molecules (Dictyostelium discoideum)
ABC-family proteins mediated transport (Dictyostelium discoideum)
ABC transporters in lipid homeostasis (Dictyostelium discoideum)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Dictyostelium discoideum)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Dictyostelium discoideum)
Plasma lipoprotein clearance (Dictyostelium discoideum)
LDL clearance (Dictyostelium discoideum)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Dictyostelium discoideum)
CHOL [transport vesicle membrane]
NCEH1 hydrolyzes cholesterol esters (Dictyostelium discoideum)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Dictyostelium discoideum)
HDL remodeling (Dictyostelium discoideum)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Dictyostelium discoideum)
CHOL [transport vesicle membrane]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Drosophila melanogaster)
CHOL [transport vesicle membrane]
Transport of small molecules (Drosophila melanogaster)
ABC-family proteins mediated transport (Drosophila melanogaster)
ABC transporters in lipid homeostasis (Drosophila melanogaster)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Drosophila melanogaster)
Plasma lipoprotein clearance (Drosophila melanogaster)
LDL clearance (Drosophila melanogaster)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Drosophila melanogaster)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Drosophila melanogaster)
HDL remodeling (Drosophila melanogaster)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)
CHOL [transport vesicle membrane]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Gallus gallus)
CHOL [transport vesicle membrane]
Transport of small molecules (Gallus gallus)
ABC-family proteins mediated transport (Gallus gallus)
ABC transporters in lipid homeostasis (Gallus gallus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Gallus gallus)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Gallus gallus)
Plasma lipoprotein assembly (Gallus gallus)
HDL assembly (Gallus gallus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Gallus gallus)
CHOL [transport vesicle membrane]
Plasma lipoprotein clearance (Gallus gallus)
LDL clearance (Gallus gallus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Gallus gallus)
CHOL [transport vesicle membrane]
NCEH1 hydrolyzes cholesterol esters (Gallus gallus)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Gallus gallus)
HDL remodeling (Gallus gallus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Gallus gallus)
CHOL [transport vesicle membrane]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
ABC transporter disorders (Homo sapiens)
Defective ABCA1 causes TGD (Homo sapiens)
Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane (Homo sapiens)
CHOL [transport vesicle membrane]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Homo sapiens)
CHOL [transport vesicle membrane]
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
ABC transporters in lipid homeostasis (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein assembly (Homo sapiens)
HDL assembly (Homo sapiens)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Homo sapiens)
CHOL [transport vesicle membrane]
Plasma lipoprotein clearance (Homo sapiens)
LDL clearance (Homo sapiens)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Homo sapiens)
CHOL [transport vesicle membrane]
NCEH1 hydrolyzes cholesterol esters (Homo sapiens)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Homo sapiens)
HDL remodeling (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
CHOL [transport vesicle membrane]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Mus musculus)
CHOL [transport vesicle membrane]
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
ABC transporters in lipid homeostasis (Mus musculus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Mus musculus)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Mus musculus)
Plasma lipoprotein assembly (Mus musculus)
HDL assembly (Mus musculus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Mus musculus)
CHOL [transport vesicle membrane]
Plasma lipoprotein clearance (Mus musculus)
LDL clearance (Mus musculus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Mus musculus)
CHOL [transport vesicle membrane]
NCEH1 hydrolyzes cholesterol esters (Mus musculus)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Mus musculus)
HDL remodeling (Mus musculus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Mus musculus)
CHOL [transport vesicle membrane]
Transport of small molecules (Rattus norvegicus)
ABC-family proteins mediated transport (Rattus norvegicus)
ABC transporters in lipid homeostasis (Rattus norvegicus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Rattus norvegicus)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Rattus norvegicus)
Plasma lipoprotein assembly (Rattus norvegicus)
HDL assembly (Rattus norvegicus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Rattus norvegicus)
CHOL [transport vesicle membrane]
Plasma lipoprotein clearance (Rattus norvegicus)
LDL clearance (Rattus norvegicus)
NCEH1 hydrolyzes cholesterol esters (Rattus norvegicus)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Rattus norvegicus)
HDL remodeling (Rattus norvegicus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Rattus norvegicus)
CHOL [transport vesicle membrane]
Transport of small molecules (Saccharomyces cerevisiae)
ABC-family proteins mediated transport (Saccharomyces cerevisiae)
ABC transporters in lipid homeostasis (Saccharomyces cerevisiae)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Saccharomyces cerevisiae)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Saccharomyces cerevisiae)
Plasma lipoprotein remodeling (Saccharomyces cerevisiae)
HDL remodeling (Saccharomyces cerevisiae)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Saccharomyces cerevisiae)
CHOL [transport vesicle membrane]
Transport of small molecules (Schizosaccharomyces pombe)
Plasma lipoprotein assembly, remodeling, and clearance (Schizosaccharomyces pombe)
Plasma lipoprotein clearance (Schizosaccharomyces pombe)
LDL clearance (Schizosaccharomyces pombe)
NCEH1 hydrolyzes cholesterol esters (Schizosaccharomyces pombe)
CHOL [transport vesicle membrane]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Sus scrofa)
CHOL [transport vesicle membrane]
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
ABC transporters in lipid homeostasis (Sus scrofa)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Sus scrofa)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Sus scrofa)
Plasma lipoprotein assembly (Sus scrofa)
HDL assembly (Sus scrofa)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Sus scrofa)
CHOL [transport vesicle membrane]
Plasma lipoprotein clearance (Sus scrofa)
LDL clearance (Sus scrofa)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Sus scrofa)
CHOL [transport vesicle membrane]
NCEH1 hydrolyzes cholesterol esters (Sus scrofa)
CHOL [transport vesicle membrane]
Plasma lipoprotein remodeling (Sus scrofa)
HDL remodeling (Sus scrofa)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Sus scrofa)
CHOL [transport vesicle membrane]
Transport of small molecules (Xenopus tropicalis)
ABC-family proteins mediated transport (Xenopus tropicalis)
ABC transporters in lipid homeostasis (Xenopus tropicalis)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Xenopus tropicalis)
CHOL [transport vesicle membrane]
Plasma lipoprotein assembly, remodeling, and clearance (Xenopus tropicalis)
Plasma lipoprotein remodeling (Xenopus tropicalis)
HDL remodeling (Xenopus tropicalis)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Xenopus tropicalis)
CHOL [transport vesicle membrane]
External Reference Information
External Reference
cholesterol [ChEBI:16113]
Participates
as an input of
Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane (Homo sapiens)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Gallus gallus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Danio rerio)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Sus scrofa)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Bos taurus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Canis familiaris)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Rattus norvegicus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Mus musculus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Saccharomyces cerevisiae)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Dictyostelium discoideum)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Gallus gallus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Xenopus tropicalis)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Sus scrofa)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Bos taurus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Canis familiaris)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Rattus norvegicus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Mus musculus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
as an output of
NCEH1 hydrolyzes cholesterol esters (Schizosaccharomyces pombe)
NCEH1 hydrolyzes cholesterol esters (Dictyostelium discoideum)
NCEH1 hydrolyzes cholesterol esters (Caenorhabditis elegans)
NCEH1 hydrolyzes cholesterol esters (Gallus gallus)
NCEH1 hydrolyzes cholesterol esters (Danio rerio)
NCEH1 hydrolyzes cholesterol esters (Sus scrofa)
NCEH1 hydrolyzes cholesterol esters (Bos taurus)
NCEH1 hydrolyzes cholesterol esters (Canis familiaris)
NCEH1 hydrolyzes cholesterol esters (Rattus norvegicus)
NCEH1 hydrolyzes cholesterol esters (Mus musculus)
NCEH1 hydrolyzes cholesterol esters (Homo sapiens)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Dictyostelium discoideum)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Caenorhabditis elegans)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Drosophila melanogaster)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Gallus gallus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Danio rerio)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Sus scrofa)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Bos taurus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Mus musculus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Homo sapiens)
Other forms of this molecule
CHOL [lipid droplet]
CHOL [early endosome]
CHOL [mitochondrial matrix]
CHOL [cornified envelope]
cholesterol [mitochondrial intermembrane space]
CHOL [mitochondrial outer membrane]
CHOL [mitochondrial inner membrane]
CHOL [lysosomal membrane]
cholesterol [endosome lumen]
cholesterol [endosome membrane]
cholesterol [clathrin-coated endocytic vesicle membrane]
CHOL [endoplasmic reticulum lumen]
CHOL [smooth endoplasmic reticulum]
CHOL [lysosomal lumen]
CHOL [cytosol]
cholesterol [endocytic vesicle lumen]
CHOL [plasma membrane]
CHOL [endoplasmic reticulum membrane]
CHOL [extracellular region]
Cross References
Guide to Pharmacology - Ligands
2718
COMPOUND
C00187
PubChem Substance
8145005
HMDB Metabolite
HMDB0000067
ZINC
000003875383
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