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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
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Content Service
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Advanced Data Search
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Search ...
Go!
CHOL [cytosol]
Stable Identifier
R-ALL-176478
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
cholesterol
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Developmental Biology (Bos taurus)
Keratinization (Bos taurus)
Formation of the cornified envelope (Bos taurus)
CASP14 cleaves filaggrin (Bos taurus)
Late cornified envelope [plasma membrane] (Bos taurus)
Cornified envelope:CDSN [plasma membrane] (Bos taurus)
Cornified envelope [plasma membrane] (Bos taurus)
Lamellar body [cytosol]
CHOL [cytosol]
Mature cornified envelope [plasma membrane] (Bos taurus)
No FGN-cornified envelope:CDSN [plasma membrane] (Bos taurus)
No FGN-Cornified envelope [plasma membrane] (Bos taurus)
Lamellar body [cytosol]
CHOL [cytosol]
CDSN binds the cornified envelope (Bos taurus)
Cornified envelope [plasma membrane] (Bos taurus)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope:CDSN [plasma membrane] (Bos taurus)
Cornified envelope [plasma membrane] (Bos taurus)
Lamellar body [cytosol]
CHOL [cytosol]
Lamellar bodies bind the early cornified envelope (Bos taurus)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope [plasma membrane] (Bos taurus)
Lamellar body [cytosol]
CHOL [cytosol]
Plasma membrane resorption (Bos taurus)
Mature cornified envelope [plasma membrane] (Bos taurus)
No FGN-cornified envelope:CDSN [plasma membrane] (Bos taurus)
No FGN-Cornified envelope [plasma membrane] (Bos taurus)
Lamellar body [cytosol]
CHOL [cytosol]
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase II - Conjugation of compounds (Bos taurus)
Cytosolic sulfonation of small molecules (Bos taurus)
cholesterol + PAPS => cholesterol sulfate + PAP (Bos taurus)
CHOL [cytosol]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Metabolism of steroid hormones (Bos taurus)
Pregnenolone biosynthesis (Bos taurus)
CHOL translocates from cytosol to mitochondrial intermembrane space (Bos taurus)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Bos taurus)
CHOL [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of fat-soluble vitamins (Bos taurus)
Retinoid metabolism and transport (Bos taurus)
Cytosolic CMs translocate to extracellular region (Bos taurus)
nascent CM:atREs [cytosol] (Bos taurus)
nascent CM [cytosol] (Bos taurus)
CHOL [cytosol]
atREs binds to nascent CM (Bos taurus)
nascent CM [cytosol] (Bos taurus)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Bos taurus)
nascent CM [cytosol] (Bos taurus)
CHOL [cytosol]
Sensory Perception (Bos taurus)
Visual phototransduction (Bos taurus)
Retinoid metabolism and transport (Bos taurus)
Cytosolic CMs translocate to extracellular region (Bos taurus)
nascent CM:atREs [cytosol] (Bos taurus)
nascent CM [cytosol] (Bos taurus)
CHOL [cytosol]
atREs binds to nascent CM (Bos taurus)
nascent CM [cytosol] (Bos taurus)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Bos taurus)
nascent CM [cytosol] (Bos taurus)
CHOL [cytosol]
Transport of small molecules (Bos taurus)
ABC-family proteins mediated transport (Bos taurus)
ABC transporters in lipid homeostasis (Bos taurus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Bos taurus)
CHOL [cytosol]
ABCG4 may mediate cholesterol efflux (Bos taurus)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Bos taurus)
sterols [cytosol]
CHOL [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of lipids (Caenorhabditis elegans)
Metabolism of steroids (Caenorhabditis elegans)
Bile acid and bile salt metabolism (Caenorhabditis elegans)
Synthesis of bile acids and bile salts (Caenorhabditis elegans)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Caenorhabditis elegans)
CHOL [cytosol]
Transport of small molecules (Caenorhabditis elegans)
ABC-family proteins mediated transport (Caenorhabditis elegans)
ABC transporters in lipid homeostasis (Caenorhabditis elegans)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Caenorhabditis elegans)
sterols [cytosol]
CHOL [cytosol]
Developmental Biology (Canis familiaris)
Keratinization (Canis familiaris)
Formation of the cornified envelope (Canis familiaris)
CASP14 cleaves filaggrin (Canis familiaris)
Late cornified envelope [plasma membrane] (Canis familiaris)
Cornified envelope:CDSN [plasma membrane] (Canis familiaris)
Cornified envelope [plasma membrane] (Canis familiaris)
Lamellar body [cytosol]
CHOL [cytosol]
Mature cornified envelope [plasma membrane] (Canis familiaris)
No FGN-cornified envelope:CDSN [plasma membrane] (Canis familiaris)
No FGN-Cornified envelope [plasma membrane] (Canis familiaris)
Lamellar body [cytosol]
CHOL [cytosol]
CDSN binds the cornified envelope (Canis familiaris)
Cornified envelope [plasma membrane] (Canis familiaris)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope:CDSN [plasma membrane] (Canis familiaris)
Cornified envelope [plasma membrane] (Canis familiaris)
Lamellar body [cytosol]
CHOL [cytosol]
Lamellar bodies bind the early cornified envelope (Canis familiaris)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope [plasma membrane] (Canis familiaris)
Lamellar body [cytosol]
CHOL [cytosol]
Plasma membrane resorption (Canis familiaris)
Mature cornified envelope [plasma membrane] (Canis familiaris)
No FGN-cornified envelope:CDSN [plasma membrane] (Canis familiaris)
No FGN-Cornified envelope [plasma membrane] (Canis familiaris)
Lamellar body [cytosol]
CHOL [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase II - Conjugation of compounds (Canis familiaris)
Cytosolic sulfonation of small molecules (Canis familiaris)
cholesterol + PAPS => cholesterol sulfate + PAP (Canis familiaris)
CHOL [cytosol]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Metabolism of steroid hormones (Canis familiaris)
Pregnenolone biosynthesis (Canis familiaris)
CHOL translocates from cytosol to mitochondrial intermembrane space (Canis familiaris)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Canis familiaris)
CHOL [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of fat-soluble vitamins (Canis familiaris)
Retinoid metabolism and transport (Canis familiaris)
Cytosolic CMs translocate to extracellular region (Canis familiaris)
nascent CM:atREs [cytosol] (Canis familiaris)
nascent CM [cytosol] (Canis familiaris)
CHOL [cytosol]
atREs binds to nascent CM (Canis familiaris)
nascent CM [cytosol] (Canis familiaris)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Canis familiaris)
nascent CM [cytosol] (Canis familiaris)
CHOL [cytosol]
Sensory Perception (Canis familiaris)
Visual phototransduction (Canis familiaris)
Retinoid metabolism and transport (Canis familiaris)
Cytosolic CMs translocate to extracellular region (Canis familiaris)
nascent CM:atREs [cytosol] (Canis familiaris)
nascent CM [cytosol] (Canis familiaris)
CHOL [cytosol]
atREs binds to nascent CM (Canis familiaris)
nascent CM [cytosol] (Canis familiaris)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Canis familiaris)
nascent CM [cytosol] (Canis familiaris)
CHOL [cytosol]
Transport of small molecules (Canis familiaris)
ABC-family proteins mediated transport (Canis familiaris)
ABC transporters in lipid homeostasis (Canis familiaris)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Canis familiaris)
CHOL [cytosol]
ABCG4 may mediate cholesterol efflux (Canis familiaris)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Canis familiaris)
sterols [cytosol]
CHOL [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Cytosolic sulfonation of small molecules (Danio rerio)
cholesterol + PAPS => cholesterol sulfate + PAP (Danio rerio)
CHOL [cytosol]
Metabolism of lipids (Danio rerio)
Metabolism of steroids (Danio rerio)
Bile acid and bile salt metabolism (Danio rerio)
Synthesis of bile acids and bile salts (Danio rerio)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Danio rerio)
CHOL [cytosol]
Metabolism of steroid hormones (Danio rerio)
Pregnenolone biosynthesis (Danio rerio)
CHOL translocates from cytosol to mitochondrial intermembrane space (Danio rerio)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Danio rerio)
CHOL [cytosol]
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
ABC transporters in lipid homeostasis (Danio rerio)
ABCG4 may mediate cholesterol efflux (Danio rerio)
CHOL [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Metabolism of steroids (Dictyostelium discoideum)
Bile acid and bile salt metabolism (Dictyostelium discoideum)
Synthesis of bile acids and bile salts (Dictyostelium discoideum)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Dictyostelium discoideum)
CHOL [cytosol]
Transport of small molecules (Dictyostelium discoideum)
ABC-family proteins mediated transport (Dictyostelium discoideum)
ABC transporters in lipid homeostasis (Dictyostelium discoideum)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Dictyostelium discoideum)
CHOL [cytosol]
ABCAs mediate lipid efflux (Dictyostelium discoideum)
CHOL [cytosol]
ABCAs mediate lipid influx (Dictyostelium discoideum)
CHOL [cytosol]
ABCG4 may mediate cholesterol efflux (Dictyostelium discoideum)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Dictyostelium discoideum)
sterols [cytosol]
CHOL [cytosol]
Drosophila signaling pathways (Drosophila melanogaster)
Hedgehog pathway (Drosophila melanogaster)
Formation and transport of the N-HH ligand (Drosophila melanogaster)
Autocleavage of HH (Drosophila melanogaster)
CHOL [cytosol]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase II - Conjugation of compounds (Drosophila melanogaster)
Cytosolic sulfonation of small molecules (Drosophila melanogaster)
cholesterol + PAPS => cholesterol sulfate + PAP (Drosophila melanogaster)
CHOL [cytosol]
Transport of small molecules (Drosophila melanogaster)
ABC-family proteins mediated transport (Drosophila melanogaster)
ABC transporters in lipid homeostasis (Drosophila melanogaster)
ABCG4 may mediate cholesterol efflux (Drosophila melanogaster)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Drosophila melanogaster)
sterols [cytosol]
CHOL [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase II - Conjugation of compounds (Gallus gallus)
Cytosolic sulfonation of small molecules (Gallus gallus)
cholesterol + PAPS => cholesterol sulfate + PAP (Gallus gallus)
CHOL [cytosol]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Bile acid and bile salt metabolism (Gallus gallus)
Synthesis of bile acids and bile salts (Gallus gallus)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Gallus gallus)
CHOL [cytosol]
Metabolism of steroid hormones (Gallus gallus)
Pregnenolone biosynthesis (Gallus gallus)
CHOL translocates from cytosol to mitochondrial intermembrane space (Gallus gallus)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Gallus gallus)
CHOL [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of fat-soluble vitamins (Gallus gallus)
Retinoid metabolism and transport (Gallus gallus)
Cytosolic CMs translocate to extracellular region (Gallus gallus)
nascent CM:atREs [cytosol] (Gallus gallus)
nascent CM [cytosol] (Gallus gallus)
CHOL [cytosol]
atREs binds to nascent CM (Gallus gallus)
nascent CM [cytosol] (Gallus gallus)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Gallus gallus)
nascent CM [cytosol] (Gallus gallus)
CHOL [cytosol]
Sensory Perception (Gallus gallus)
Visual phototransduction (Gallus gallus)
Retinoid metabolism and transport (Gallus gallus)
Cytosolic CMs translocate to extracellular region (Gallus gallus)
nascent CM:atREs [cytosol] (Gallus gallus)
nascent CM [cytosol] (Gallus gallus)
CHOL [cytosol]
atREs binds to nascent CM (Gallus gallus)
nascent CM [cytosol] (Gallus gallus)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Gallus gallus)
nascent CM [cytosol] (Gallus gallus)
CHOL [cytosol]
Transport of small molecules (Gallus gallus)
ABC-family proteins mediated transport (Gallus gallus)
ABC transporters in lipid homeostasis (Gallus gallus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Gallus gallus)
CHOL [cytosol]
ABCAs mediate lipid efflux (Gallus gallus)
CHOL [cytosol]
ABCAs mediate lipid influx (Gallus gallus)
CHOL [cytosol]
ABCG4 may mediate cholesterol efflux (Gallus gallus)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Gallus gallus)
sterols [cytosol]
CHOL [cytosol]
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
CDSN binds the cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
Lamellar bodies bind the early cornified envelope (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope [plasma membrane] (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
Lamellar body [cytosol]
CHOL [cytosol]
Digestion and absorption (Homo sapiens)
Intestinal absorption (Homo sapiens)
Intestinal lipid absorption (Homo sapiens)
NPC1L1-mediated cholesterol uptake (Homo sapiens)
CHOL [cytosol]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
ABC transporter disorders (Homo sapiens)
Defective ABCG5 causes sitosterolemia (Homo sapiens)
Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region (Homo sapiens)
sterols [cytosol]
CHOL [cytosol]
Defective ABCG8 causes GBD4 and sitosterolemia (Homo sapiens)
Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region (Homo sapiens)
sterols [cytosol]
CHOL [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
cholesterol + PAPS => cholesterol sulfate + PAP (Homo sapiens)
CHOL [cytosol]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Synthesis of bile acids and bile salts (Homo sapiens)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Homo sapiens)
CHOL [cytosol]
Metabolism of steroid hormones (Homo sapiens)
Pregnenolone biosynthesis (Homo sapiens)
CHOL translocates from cytosol to mitochondrial intermembrane space (Homo sapiens)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Homo sapiens)
CHOL [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of fat-soluble vitamins (Homo sapiens)
Retinoid metabolism and transport (Homo sapiens)
Cytosolic CMs translocate to extracellular region (Homo sapiens)
nascent CM:atREs [cytosol] (Homo sapiens)
nascent CM [cytosol] (Homo sapiens)
CHOL [cytosol]
atREs binds to nascent CM (Homo sapiens)
nascent CM [cytosol] (Homo sapiens)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Homo sapiens)
nascent CM [cytosol] (Homo sapiens)
CHOL [cytosol]
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
Retinoid metabolism and transport (Homo sapiens)
Cytosolic CMs translocate to extracellular region (Homo sapiens)
nascent CM:atREs [cytosol] (Homo sapiens)
nascent CM [cytosol] (Homo sapiens)
CHOL [cytosol]
atREs binds to nascent CM (Homo sapiens)
nascent CM [cytosol] (Homo sapiens)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Homo sapiens)
nascent CM [cytosol] (Homo sapiens)
CHOL [cytosol]
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
ABC transporters in lipid homeostasis (Homo sapiens)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Homo sapiens)
CHOL [cytosol]
ABCAs mediate lipid efflux (Homo sapiens)
CHOL [cytosol]
ABCAs mediate lipid influx (Homo sapiens)
CHOL [cytosol]
ABCG4 may mediate cholesterol efflux (Homo sapiens)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Homo sapiens)
sterols [cytosol]
CHOL [cytosol]
Developmental Biology (Mus musculus)
Keratinization (Mus musculus)
Formation of the cornified envelope (Mus musculus)
CASP14 cleaves filaggrin (Mus musculus)
Late cornified envelope [plasma membrane] (Mus musculus)
Cornified envelope:CDSN [plasma membrane] (Mus musculus)
Cornified envelope [plasma membrane] (Mus musculus)
Lamellar body [cytosol]
CHOL [cytosol]
Mature cornified envelope [plasma membrane] (Mus musculus)
No FGN-cornified envelope:CDSN [plasma membrane] (Mus musculus)
No FGN-Cornified envelope [plasma membrane] (Mus musculus)
Lamellar body [cytosol]
CHOL [cytosol]
CDSN binds the cornified envelope (Mus musculus)
Cornified envelope [plasma membrane] (Mus musculus)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope:CDSN [plasma membrane] (Mus musculus)
Cornified envelope [plasma membrane] (Mus musculus)
Lamellar body [cytosol]
CHOL [cytosol]
Lamellar bodies bind the early cornified envelope (Mus musculus)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope [plasma membrane] (Mus musculus)
Lamellar body [cytosol]
CHOL [cytosol]
Plasma membrane resorption (Mus musculus)
Mature cornified envelope [plasma membrane] (Mus musculus)
No FGN-cornified envelope:CDSN [plasma membrane] (Mus musculus)
No FGN-Cornified envelope [plasma membrane] (Mus musculus)
Lamellar body [cytosol]
CHOL [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase II - Conjugation of compounds (Mus musculus)
Cytosolic sulfonation of small molecules (Mus musculus)
cholesterol + PAPS => cholesterol sulfate + PAP (Mus musculus)
CHOL [cytosol]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Synthesis of bile acids and bile salts (Mus musculus)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Mus musculus)
CHOL [cytosol]
Metabolism of steroid hormones (Mus musculus)
Pregnenolone biosynthesis (Mus musculus)
CHOL translocates from cytosol to mitochondrial intermembrane space (Mus musculus)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Mus musculus)
CHOL [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of fat-soluble vitamins (Mus musculus)
Retinoid metabolism and transport (Mus musculus)
Cytosolic CMs translocate to extracellular region (Mus musculus)
nascent CM:atREs [cytosol] (Mus musculus)
nascent CM [cytosol] (Mus musculus)
CHOL [cytosol]
atREs binds to nascent CM (Mus musculus)
nascent CM [cytosol] (Mus musculus)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Mus musculus)
nascent CM [cytosol] (Mus musculus)
CHOL [cytosol]
Sensory Perception (Mus musculus)
Visual phototransduction (Mus musculus)
Retinoid metabolism and transport (Mus musculus)
Cytosolic CMs translocate to extracellular region (Mus musculus)
nascent CM:atREs [cytosol] (Mus musculus)
nascent CM [cytosol] (Mus musculus)
CHOL [cytosol]
atREs binds to nascent CM (Mus musculus)
nascent CM [cytosol] (Mus musculus)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Mus musculus)
nascent CM [cytosol] (Mus musculus)
CHOL [cytosol]
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
ABC transporters in lipid homeostasis (Mus musculus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Mus musculus)
CHOL [cytosol]
ABCAs mediate lipid efflux (Mus musculus)
CHOL [cytosol]
ABCAs mediate lipid influx (Mus musculus)
CHOL [cytosol]
ABCG4 may mediate cholesterol efflux (Mus musculus)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Mus musculus)
sterols [cytosol]
CHOL [cytosol]
Transport of small molecules (Plasmodium falciparum)
ABC-family proteins mediated transport (Plasmodium falciparum)
ABC transporters in lipid homeostasis (Plasmodium falciparum)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Plasmodium falciparum)
CHOL [cytosol]
ABCAs mediate lipid efflux (Plasmodium falciparum)
CHOL [cytosol]
ABCAs mediate lipid influx (Plasmodium falciparum)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Plasmodium falciparum)
sterols [cytosol]
CHOL [cytosol]
Developmental Biology (Rattus norvegicus)
Keratinization (Rattus norvegicus)
Formation of the cornified envelope (Rattus norvegicus)
CASP14 cleaves filaggrin (Rattus norvegicus)
Late cornified envelope [plasma membrane] (Rattus norvegicus)
Cornified envelope:CDSN [plasma membrane] (Rattus norvegicus)
Cornified envelope [plasma membrane] (Rattus norvegicus)
Lamellar body [cytosol]
CHOL [cytosol]
Mature cornified envelope [plasma membrane] (Rattus norvegicus)
No FGN-cornified envelope:CDSN [plasma membrane] (Rattus norvegicus)
No FGN-Cornified envelope [plasma membrane] (Rattus norvegicus)
Lamellar body [cytosol]
CHOL [cytosol]
CDSN binds the cornified envelope (Rattus norvegicus)
Cornified envelope [plasma membrane] (Rattus norvegicus)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope:CDSN [plasma membrane] (Rattus norvegicus)
Cornified envelope [plasma membrane] (Rattus norvegicus)
Lamellar body [cytosol]
CHOL [cytosol]
Lamellar bodies bind the early cornified envelope (Rattus norvegicus)
Lamellar body [cytosol]
CHOL [cytosol]
Cornified envelope [plasma membrane] (Rattus norvegicus)
Lamellar body [cytosol]
CHOL [cytosol]
Plasma membrane resorption (Rattus norvegicus)
Mature cornified envelope [plasma membrane] (Rattus norvegicus)
No FGN-cornified envelope:CDSN [plasma membrane] (Rattus norvegicus)
No FGN-Cornified envelope [plasma membrane] (Rattus norvegicus)
Lamellar body [cytosol]
CHOL [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase II - Conjugation of compounds (Rattus norvegicus)
Cytosolic sulfonation of small molecules (Rattus norvegicus)
cholesterol + PAPS => cholesterol sulfate + PAP (Rattus norvegicus)
CHOL [cytosol]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Rattus norvegicus)
CHOL [cytosol]
Metabolism of steroid hormones (Rattus norvegicus)
Pregnenolone biosynthesis (Rattus norvegicus)
CHOL translocates from cytosol to mitochondrial intermembrane space (Rattus norvegicus)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Rattus norvegicus)
CHOL [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of fat-soluble vitamins (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
Cytosolic CMs translocate to extracellular region (Rattus norvegicus)
nascent CM:atREs [cytosol] (Rattus norvegicus)
nascent CM [cytosol] (Rattus norvegicus)
CHOL [cytosol]
atREs binds to nascent CM (Rattus norvegicus)
nascent CM [cytosol] (Rattus norvegicus)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Rattus norvegicus)
nascent CM [cytosol] (Rattus norvegicus)
CHOL [cytosol]
Sensory Perception (Rattus norvegicus)
Visual phototransduction (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
Cytosolic CMs translocate to extracellular region (Rattus norvegicus)
nascent CM:atREs [cytosol] (Rattus norvegicus)
nascent CM [cytosol] (Rattus norvegicus)
CHOL [cytosol]
atREs binds to nascent CM (Rattus norvegicus)
nascent CM [cytosol] (Rattus norvegicus)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Rattus norvegicus)
nascent CM [cytosol] (Rattus norvegicus)
CHOL [cytosol]
Transport of small molecules (Rattus norvegicus)
ABC-family proteins mediated transport (Rattus norvegicus)
ABC transporters in lipid homeostasis (Rattus norvegicus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Rattus norvegicus)
CHOL [cytosol]
ABCAs mediate lipid efflux (Rattus norvegicus)
CHOL [cytosol]
ABCAs mediate lipid influx (Rattus norvegicus)
CHOL [cytosol]
ABCG4 may mediate cholesterol efflux (Rattus norvegicus)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Rattus norvegicus)
sterols [cytosol]
CHOL [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Metabolism of steroids (Saccharomyces cerevisiae)
Bile acid and bile salt metabolism (Saccharomyces cerevisiae)
Synthesis of bile acids and bile salts (Saccharomyces cerevisiae)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Saccharomyces cerevisiae)
CHOL [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
ABC-family proteins mediated transport (Saccharomyces cerevisiae)
ABC transporters in lipid homeostasis (Saccharomyces cerevisiae)
ABCG4 may mediate cholesterol efflux (Saccharomyces cerevisiae)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Saccharomyces cerevisiae)
sterols [cytosol]
CHOL [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Metabolism of steroids (Schizosaccharomyces pombe)
Bile acid and bile salt metabolism (Schizosaccharomyces pombe)
Synthesis of bile acids and bile salts (Schizosaccharomyces pombe)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Schizosaccharomyces pombe)
CHOL [cytosol]
Developmental Biology (Sus scrofa)
Keratinization (Sus scrofa)
Formation of the cornified envelope (Sus scrofa)
Plasma membrane resorption (Sus scrofa)
Mature cornified envelope [plasma membrane] (Sus scrofa)
No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
Lamellar body [cytosol]
CHOL [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase II - Conjugation of compounds (Sus scrofa)
Cytosolic sulfonation of small molecules (Sus scrofa)
cholesterol + PAPS => cholesterol sulfate + PAP (Sus scrofa)
CHOL [cytosol]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Bile acid and bile salt metabolism (Sus scrofa)
Synthesis of bile acids and bile salts (Sus scrofa)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Sus scrofa)
CHOL [cytosol]
Metabolism of steroid hormones (Sus scrofa)
Pregnenolone biosynthesis (Sus scrofa)
CHOL translocates from cytosol to mitochondrial intermembrane space (Sus scrofa)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Sus scrofa)
CHOL [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of fat-soluble vitamins (Sus scrofa)
Retinoid metabolism and transport (Sus scrofa)
Cytosolic CMs translocate to extracellular region (Sus scrofa)
nascent CM:atREs [cytosol] (Sus scrofa)
nascent CM [cytosol] (Sus scrofa)
CHOL [cytosol]
atREs binds to nascent CM (Sus scrofa)
nascent CM [cytosol] (Sus scrofa)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Sus scrofa)
nascent CM [cytosol] (Sus scrofa)
CHOL [cytosol]
Sensory Perception (Sus scrofa)
Visual phototransduction (Sus scrofa)
Retinoid metabolism and transport (Sus scrofa)
Cytosolic CMs translocate to extracellular region (Sus scrofa)
nascent CM:atREs [cytosol] (Sus scrofa)
nascent CM [cytosol] (Sus scrofa)
CHOL [cytosol]
atREs binds to nascent CM (Sus scrofa)
nascent CM [cytosol] (Sus scrofa)
CHOL [cytosol]
nascent CM:atREs [cytosol] (Sus scrofa)
nascent CM [cytosol] (Sus scrofa)
CHOL [cytosol]
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
ABC transporters in lipid homeostasis (Sus scrofa)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Sus scrofa)
CHOL [cytosol]
ABCAs mediate lipid efflux (Sus scrofa)
CHOL [cytosol]
ABCAs mediate lipid influx (Sus scrofa)
CHOL [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Sus scrofa)
sterols [cytosol]
CHOL [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase II - Conjugation of compounds (Xenopus tropicalis)
Cytosolic sulfonation of small molecules (Xenopus tropicalis)
cholesterol + PAPS => cholesterol sulfate + PAP (Xenopus tropicalis)
CHOL [cytosol]
Metabolism of lipids (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Bile acid and bile salt metabolism (Xenopus tropicalis)
Synthesis of bile acids and bile salts (Xenopus tropicalis)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Xenopus tropicalis)
CHOL [cytosol]
Metabolism of steroid hormones (Xenopus tropicalis)
Pregnenolone biosynthesis (Xenopus tropicalis)
CHOL translocates from cytosol to mitochondrial intermembrane space (Xenopus tropicalis)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Xenopus tropicalis)
CHOL [cytosol]
Transport of small molecules (Xenopus tropicalis)
ABC-family proteins mediated transport (Xenopus tropicalis)
ABC transporters in lipid homeostasis (Xenopus tropicalis)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Xenopus tropicalis)
CHOL [cytosol]
ABCG4 may mediate cholesterol efflux (Xenopus tropicalis)
CHOL [cytosol]
External Reference Information
External Reference
cholesterol [ChEBI:16113]
Participates
as a component of
CR:atREs [cytosol] (Mus musculus)
nascent CM [cytosol] (Sus scrofa)
nascent CM [cytosol] (Bos taurus)
nascent CM [cytosol] (Canis familiaris)
nascent CM [cytosol] (Rattus norvegicus)
nascent CM [cytosol] (Mus musculus)
nascent CM [cytosol] (Gallus gallus)
nascent CM [cytosol] (Homo sapiens)
Lamellar body [cytosol]
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Xenopus tropicalis)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Sus scrofa)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Canis familiaris)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Danio rerio)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Gallus gallus)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Bos taurus)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Rattus norvegicus)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Mus musculus)
STARD3:STARD3NL, STARD4,6:CHOL [cytosol] (Homo sapiens)
as an input of
Autocleavage of HH (Drosophila melanogaster)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Saccharomyces cerevisiae)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Schizosaccharomyces pombe)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Dictyostelium discoideum)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Caenorhabditis elegans)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Gallus gallus)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Xenopus tropicalis)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Danio rerio)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Sus scrofa)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Rattus norvegicus)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Mus musculus)
Cholesterol is hydroxylated to 25-hydroxycholesterol (Homo sapiens)
cholesterol + PAPS => cholesterol sulfate + PAP (Drosophila melanogaster)
ABCAs mediate lipid efflux (Homo sapiens)
ABCAs mediate lipid efflux (Mus musculus)
ABCAs mediate lipid efflux (Rattus norvegicus)
ABCAs mediate lipid efflux (Sus scrofa)
ABCAs mediate lipid efflux (Gallus gallus)
ABCAs mediate lipid efflux (Dictyostelium discoideum)
ABCAs mediate lipid efflux (Plasmodium falciparum)
ABCG4 may mediate cholesterol efflux (Homo sapiens)
ABCG4 may mediate cholesterol efflux (Mus musculus)
ABCG4 may mediate cholesterol efflux (Rattus norvegicus)
ABCG4 may mediate cholesterol efflux (Canis familiaris)
ABCG4 may mediate cholesterol efflux (Bos taurus)
ABCG4 may mediate cholesterol efflux (Danio rerio)
ABCG4 may mediate cholesterol efflux (Xenopus tropicalis)
ABCG4 may mediate cholesterol efflux (Gallus gallus)
ABCG4 may mediate cholesterol efflux (Drosophila melanogaster)
ABCG4 may mediate cholesterol efflux (Dictyostelium discoideum)
ABCG4 may mediate cholesterol efflux (Saccharomyces cerevisiae)
cholesterol + PAPS => cholesterol sulfate + PAP (Homo sapiens)
cholesterol + PAPS => cholesterol sulfate + PAP (Mus musculus)
cholesterol + PAPS => cholesterol sulfate + PAP (Rattus norvegicus)
cholesterol + PAPS => cholesterol sulfate + PAP (Canis familiaris)
cholesterol + PAPS => cholesterol sulfate + PAP (Bos taurus)
cholesterol + PAPS => cholesterol sulfate + PAP (Sus scrofa)
cholesterol + PAPS => cholesterol sulfate + PAP (Danio rerio)
cholesterol + PAPS => cholesterol sulfate + PAP (Xenopus tropicalis)
cholesterol + PAPS => cholesterol sulfate + PAP (Gallus gallus)
as an output of
NPC1L1-mediated cholesterol uptake (Canis familiaris)
NPC1L1-mediated cholesterol uptake (Homo sapiens)
ABCAs mediate lipid influx (Homo sapiens)
ABCAs mediate lipid influx (Mus musculus)
ABCAs mediate lipid influx (Rattus norvegicus)
ABCAs mediate lipid influx (Sus scrofa)
ABCAs mediate lipid influx (Gallus gallus)
ABCAs mediate lipid influx (Dictyostelium discoideum)
ABCAs mediate lipid influx (Plasmodium falciparum)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Homo sapiens)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Mus musculus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Rattus norvegicus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Canis familiaris)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Bos taurus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Sus scrofa)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Xenopus tropicalis)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Gallus gallus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Dictyostelium discoideum)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Plasmodium falciparum)
as a member of
sterols [cytosol]
Other forms of this molecule
CHOL [lipid droplet]
CHOL [early endosome]
CHOL [mitochondrial matrix]
CHOL [cornified envelope]
cholesterol [mitochondrial intermembrane space]
CHOL [mitochondrial outer membrane]
CHOL [mitochondrial inner membrane]
CHOL [lysosomal membrane]
cholesterol [endosome lumen]
cholesterol [endosome membrane]
cholesterol [clathrin-coated endocytic vesicle membrane]
CHOL [endoplasmic reticulum lumen]
CHOL [smooth endoplasmic reticulum]
CHOL [transport vesicle membrane]
CHOL [lysosomal lumen]
cholesterol [endocytic vesicle lumen]
CHOL [plasma membrane]
CHOL [endoplasmic reticulum membrane]
CHOL [extracellular region]
Cross References
Guide to Pharmacology - Ligands
2718
COMPOUND
C00187
PubChem Substance
8145005
HMDB Metabolite
HMDB0000067
ZINC
000003875383
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