ABCG1-mediated transport of intracellular cholesterol to the cell surface

Stable Identifier
R-HSA-266082
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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In an ATP-dependent reaction, ABCG1 mediates the movement of intracellular cholesterol to the extracellular face of the plasma membrane. In a tissue culture model system, the active form of ABCG1 is predominantly a tetramer (Vuaghan and Oram 2005). The number of lipid molecules transported per ATP consumed is not known.

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cholesterol transfer activity of ABCG1 dimer [plasma membrane]
Physical Entity
Activity
Orthologous Events
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