ABCG1-mediated transport of intracellular cholesterol to the cell surface

Stable Identifier
R-HSA-266082
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, transport vesicle membrane
ReviewStatus
5/5
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ABCG1-mediated transport of intracellular cholesterol to the cell surface
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In an ATP-dependent reaction, ABCG1 mediates the movement of intracellular cholesterol to the extracellular face of the plasma membrane. In a tissue culture model system, the active form of ABCG1 is predominantly a tetramer (Vuaghan and Oram 2005). The number of lipid molecules transported per ATP consumed is not known.
Literature References
Participants
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Output
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as an event of
Catalyst Activity

cholesterol transfer activity of ABCG1 dimer [plasma membrane]

Physical Entity
ABCG1 dimer [plasma membrane] (Homo sapiens)
Activity
cholesterol transfer activity (GO:0120020)
Orthologous Events
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Bos taurus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Canis familiaris)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Dictyostelium discoideum)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Gallus gallus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Mus musculus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Rattus norvegicus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Saccharomyces cerevisiae)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Sus scrofa)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Xenopus tropicalis)
Authored
D'Eustachio, P  (2008-05-12)
Reviewed
Jassal, B  (2008-06-13)
Created
D'Eustachio, P  (2008-04-22)
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