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CHOL [endoplasmic reticulum lumen]
Stable Identifier
R-ALL-174672
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum lumen
Synonyms
cholesterol
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by Hedgehog (Bos taurus)
Hedgehog ligand biogenesis (Bos taurus)
Autoproteolytic cleavage of Hh precursors (Bos taurus)
CHOL [endoplasmic reticulum lumen]
Transport of small molecules (Bos taurus)
Plasma lipoprotein assembly, remodeling, and clearance (Bos taurus)
Plasma lipoprotein assembly (Bos taurus)
Chylomicron assembly (Bos taurus)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Bos taurus)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] (Bos taurus)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Bos taurus)
nascent chylomicron [endoplasmic reticulum lumen] (Bos taurus)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Canis familiaris)
Signaling by Hedgehog (Canis familiaris)
Hedgehog ligand biogenesis (Canis familiaris)
Autoproteolytic cleavage of Hh precursors (Canis familiaris)
CHOL [endoplasmic reticulum lumen]
Transport of small molecules (Canis familiaris)
Plasma lipoprotein assembly, remodeling, and clearance (Canis familiaris)
Plasma lipoprotein assembly (Canis familiaris)
Chylomicron assembly (Canis familiaris)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Canis familiaris)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] (Canis familiaris)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Canis familiaris)
nascent chylomicron [endoplasmic reticulum lumen] (Canis familiaris)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Danio rerio)
Signaling by Hedgehog (Danio rerio)
Hedgehog ligand biogenesis (Danio rerio)
Autoproteolytic cleavage of Hh precursors (Danio rerio)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Drosophila melanogaster)
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog ligand biogenesis (Drosophila melanogaster)
Autoproteolytic cleavage of Hh precursors (Drosophila melanogaster)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Gallus gallus)
Signaling by Hedgehog (Gallus gallus)
Hedgehog ligand biogenesis (Gallus gallus)
Autoproteolytic cleavage of Hh precursors (Gallus gallus)
CHOL [endoplasmic reticulum lumen]
Transport of small molecules (Gallus gallus)
Plasma lipoprotein assembly, remodeling, and clearance (Gallus gallus)
Plasma lipoprotein assembly (Gallus gallus)
Chylomicron assembly (Gallus gallus)
nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Gallus gallus)
nascent chylomicron [endoplasmic reticulum lumen] (Gallus gallus)
CHOL [endoplasmic reticulum lumen]
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Hh mutants abrogate ligand secretion (Homo sapiens)
Hh mutants are degraded by ERAD (Homo sapiens)
HPE SHH variants don't undergo autoproteolytic cleavage (Homo sapiens)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog ligand biogenesis (Homo sapiens)
Autoproteolytic cleavage of Hh precursors (Homo sapiens)
CHOL [endoplasmic reticulum lumen]
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein assembly (Homo sapiens)
Chylomicron assembly (Homo sapiens)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Homo sapiens)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] (Homo sapiens)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Homo sapiens)
nascent chylomicron [endoplasmic reticulum lumen] (Homo sapiens)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Mus musculus)
Signaling by Hedgehog (Mus musculus)
Hedgehog ligand biogenesis (Mus musculus)
Autoproteolytic cleavage of Hh precursors (Mus musculus)
CHOL [endoplasmic reticulum lumen]
Transport of small molecules (Mus musculus)
Plasma lipoprotein assembly, remodeling, and clearance (Mus musculus)
Plasma lipoprotein assembly (Mus musculus)
Chylomicron assembly (Mus musculus)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Mus musculus)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] (Mus musculus)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Mus musculus)
nascent chylomicron [endoplasmic reticulum lumen] (Mus musculus)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Rattus norvegicus)
Signaling by Hedgehog (Rattus norvegicus)
Hedgehog ligand biogenesis (Rattus norvegicus)
Autoproteolytic cleavage of Hh precursors (Rattus norvegicus)
CHOL [endoplasmic reticulum lumen]
Transport of small molecules (Rattus norvegicus)
Plasma lipoprotein assembly, remodeling, and clearance (Rattus norvegicus)
Plasma lipoprotein assembly (Rattus norvegicus)
Chylomicron assembly (Rattus norvegicus)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Rattus norvegicus)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] (Rattus norvegicus)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Rattus norvegicus)
nascent chylomicron [endoplasmic reticulum lumen] (Rattus norvegicus)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Sus scrofa)
Signaling by Hedgehog (Sus scrofa)
Hedgehog ligand biogenesis (Sus scrofa)
Autoproteolytic cleavage of Hh precursors (Sus scrofa)
CHOL [endoplasmic reticulum lumen]
Transport of small molecules (Sus scrofa)
Plasma lipoprotein assembly, remodeling, and clearance (Sus scrofa)
Plasma lipoprotein assembly (Sus scrofa)
Chylomicron assembly (Sus scrofa)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Sus scrofa)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] (Sus scrofa)
CHOL [endoplasmic reticulum lumen]
nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Sus scrofa)
nascent chylomicron [endoplasmic reticulum lumen] (Sus scrofa)
CHOL [endoplasmic reticulum lumen]
Signal Transduction (Xenopus tropicalis)
Signaling by Hedgehog (Xenopus tropicalis)
Hedgehog ligand biogenesis (Xenopus tropicalis)
Autoproteolytic cleavage of Hh precursors (Xenopus tropicalis)
CHOL [endoplasmic reticulum lumen]
External Reference Information
External Reference
cholesterol [ChEBI:16113]
Participates
as an input of
Autoproteolytic cleavage of Hh precursors (Drosophila melanogaster)
Autoproteolytic cleavage of Hh precursors (Gallus gallus)
Autoproteolytic cleavage of Hh precursors (Xenopus tropicalis)
Autoproteolytic cleavage of Hh precursors (Danio rerio)
Autoproteolytic cleavage of Hh precursors (Sus scrofa)
Autoproteolytic cleavage of Hh precursors (Bos taurus)
Autoproteolytic cleavage of Hh precursors (Canis familiaris)
Autoproteolytic cleavage of Hh precursors (Rattus norvegicus)
Autoproteolytic cleavage of Hh precursors (Mus musculus)
Autoproteolytic cleavage of Hh precursors (Homo sapiens)
HPE SHH variants don't undergo autoproteolytic cleavage (Homo sapiens)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Sus scrofa)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Bos taurus)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Canis familiaris)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Rattus norvegicus)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Mus musculus)
ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Homo sapiens)
as a component of
nascent chylomicron [endoplasmic reticulum lumen] (Canis familiaris)
nascent chylomicron [endoplasmic reticulum lumen] (Mus musculus)
nascent chylomicron [endoplasmic reticulum lumen] (Sus scrofa)
nascent chylomicron [endoplasmic reticulum lumen] (Bos taurus)
nascent chylomicron [endoplasmic reticulum lumen] (Rattus norvegicus)
nascent chylomicron [endoplasmic reticulum lumen] (Gallus gallus)
nascent chylomicron [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
CHOL [lipid droplet]
CHOL [early endosome]
CHOL [mitochondrial matrix]
CHOL [cornified envelope]
cholesterol [mitochondrial intermembrane space]
CHOL [mitochondrial outer membrane]
CHOL [mitochondrial inner membrane]
CHOL [lysosomal membrane]
cholesterol [endosome lumen]
cholesterol [endosome membrane]
cholesterol [clathrin-coated endocytic vesicle membrane]
CHOL [smooth endoplasmic reticulum]
CHOL [transport vesicle membrane]
CHOL [lysosomal lumen]
CHOL [cytosol]
cholesterol [endocytic vesicle lumen]
CHOL [plasma membrane]
CHOL [endoplasmic reticulum membrane]
CHOL [extracellular region]
Cross References
Guide to Pharmacology - Ligands
2718
COMPOUND
C00187
PubChem Substance
8145005
HMDB Metabolite
HMDB0000067
ZINC
000003875383
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