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About
What is Reactome ?
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Team
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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COVID-19 Disease Pathways
Docs
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I- [cytosol]
Stable Identifier
R-ALL-209785
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
iodide
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Metabolism of amine-derived hormones (Bos taurus)
Thyroxine biosynthesis (Bos taurus)
Iodide is taken up by thyroid epithelial cells (Bos taurus)
I- [cytosol]
Regulation of thyroid hormone activity (Bos taurus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Bos taurus)
I- [cytosol]
Thyroxine is deiodinated to triiodothyronine (Bos taurus)
I- [cytosol]
Transport of small molecules (Bos taurus)
Miscellaneous transport and binding events (Bos taurus)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Bos taurus)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Bos taurus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Multifunctional anion exchangers (Bos taurus)
SLC26A4 transports I- from cytosol to extracellular region (Bos taurus)
I- [cytosol]
Organic anion transporters (Bos taurus)
Passive I- efflux mediated by SLC5A8 (Bos taurus)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Bos taurus)
I- [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of amine-derived hormones (Caenorhabditis elegans)
Thyroxine biosynthesis (Caenorhabditis elegans)
Iodide is taken up by thyroid epithelial cells (Caenorhabditis elegans)
I- [cytosol]
Transport of small molecules (Caenorhabditis elegans)
Miscellaneous transport and binding events (Caenorhabditis elegans)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Caenorhabditis elegans)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of inorganic cations/anions and amino acids/oligopeptides (Caenorhabditis elegans)
Multifunctional anion exchangers (Caenorhabditis elegans)
SLC26A4 transports I- from cytosol to extracellular region (Caenorhabditis elegans)
I- [cytosol]
Organic anion transporters (Caenorhabditis elegans)
Passive I- efflux mediated by SLC5A8 (Caenorhabditis elegans)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Caenorhabditis elegans)
I- [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Metabolism of amine-derived hormones (Canis familiaris)
Thyroxine biosynthesis (Canis familiaris)
Iodide is taken up by thyroid epithelial cells (Canis familiaris)
I- [cytosol]
Regulation of thyroid hormone activity (Canis familiaris)
Thyroxine is deiodinated to triiodothyronine (Canis familiaris)
I- [cytosol]
Transport of small molecules (Canis familiaris)
Miscellaneous transport and binding events (Canis familiaris)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Canis familiaris)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Canis familiaris)
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Multifunctional anion exchangers (Canis familiaris)
SLC26A4 transports I- from cytosol to extracellular region (Canis familiaris)
I- [cytosol]
Organic anion transporters (Canis familiaris)
Passive I- efflux mediated by SLC5A8 (Canis familiaris)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Canis familiaris)
I- [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of amine-derived hormones (Danio rerio)
Thyroxine biosynthesis (Danio rerio)
Iodide is taken up by thyroid epithelial cells (Danio rerio)
I- [cytosol]
Transport of small molecules (Danio rerio)
Miscellaneous transport and binding events (Danio rerio)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Danio rerio)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Danio rerio)
Transport of inorganic cations/anions and amino acids/oligopeptides (Danio rerio)
Organic anion transporters (Danio rerio)
Passive I- efflux mediated by SLC5A8 (Danio rerio)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Danio rerio)
I- [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Metabolism of amine-derived hormones (Dictyostelium discoideum)
Thyroxine biosynthesis (Dictyostelium discoideum)
Regulation of thyroid hormone activity (Dictyostelium discoideum)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Dictyostelium discoideum)
I- [cytosol]
Thyroxine is deiodinated to triiodothyronine (Dictyostelium discoideum)
I- [cytosol]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of inorganic cations/anions and amino acids/oligopeptides (Dictyostelium discoideum)
Multifunctional anion exchangers (Dictyostelium discoideum)
SLC26A4 transports I- from cytosol to extracellular region (Dictyostelium discoideum)
I- [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Metabolism of amine-derived hormones (Drosophila melanogaster)
Thyroxine biosynthesis (Drosophila melanogaster)
Iodide is taken up by thyroid epithelial cells (Drosophila melanogaster)
I- [cytosol]
Transport of small molecules (Drosophila melanogaster)
Miscellaneous transport and binding events (Drosophila melanogaster)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Drosophila melanogaster)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Multifunctional anion exchangers (Drosophila melanogaster)
SLC26A4 transports I- from cytosol to extracellular region (Drosophila melanogaster)
I- [cytosol]
Organic anion transporters (Drosophila melanogaster)
Passive I- efflux mediated by SLC5A8 (Drosophila melanogaster)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Drosophila melanogaster)
I- [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Metabolism of amine-derived hormones (Gallus gallus)
Thyroxine biosynthesis (Gallus gallus)
Iodide is taken up by thyroid epithelial cells (Gallus gallus)
I- [cytosol]
Regulation of thyroid hormone activity (Gallus gallus)
Thyroxine is deiodinated to triiodothyronine (Gallus gallus)
I- [cytosol]
Transport of small molecules (Gallus gallus)
Miscellaneous transport and binding events (Gallus gallus)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Gallus gallus)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Gallus gallus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Multifunctional anion exchangers (Gallus gallus)
SLC26A4 transports I- from cytosol to extracellular region (Gallus gallus)
I- [cytosol]
Organic anion transporters (Gallus gallus)
Passive I- efflux mediated by SLC5A8 (Gallus gallus)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Gallus gallus)
I- [cytosol]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC26A4 causes Pendred syndrome (PDS) (Homo sapiens)
SLC26A4 does not transport I- from cytosol to extracellular region (Homo sapiens)
I- [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of amine-derived hormones (Homo sapiens)
Thyroxine biosynthesis (Homo sapiens)
Iodide is taken up by thyroid epithelial cells (Homo sapiens)
I- [cytosol]
Regulation of thyroid hormone activity (Homo sapiens)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Homo sapiens)
I- [cytosol]
Thyroxine is deiodinated to triiodothyronine (Homo sapiens)
I- [cytosol]
Transport of small molecules (Homo sapiens)
Aquaporin-mediated transport (Homo sapiens)
Passive transport by Aquaporins (Homo sapiens)
Aquaporin-6 passively transports anions into vesicles (Homo sapiens)
Anions transported by Aquaporin-6 [cytosol]
I- [cytosol]
Aquaporin-6 passively transports anions out of vesicles (Homo sapiens)
Anions transported by Aquaporin-6 [cytosol]
I- [cytosol]
Miscellaneous transport and binding events (Homo sapiens)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Homo sapiens)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Multifunctional anion exchangers (Homo sapiens)
SLC26A4 transports I- from cytosol to extracellular region (Homo sapiens)
I- [cytosol]
Organic anion transporters (Homo sapiens)
Passive I- efflux mediated by SLC5A8 (Homo sapiens)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Homo sapiens)
I- [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Metabolism of amine-derived hormones (Mus musculus)
Thyroxine biosynthesis (Mus musculus)
Iodide is taken up by thyroid epithelial cells (Mus musculus)
I- [cytosol]
Regulation of thyroid hormone activity (Mus musculus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Mus musculus)
I- [cytosol]
Thyroxine is deiodinated to triiodothyronine (Mus musculus)
I- [cytosol]
Transport of small molecules (Mus musculus)
Miscellaneous transport and binding events (Mus musculus)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Mus musculus)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Mus musculus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Mus musculus)
Multifunctional anion exchangers (Mus musculus)
SLC26A4 transports I- from cytosol to extracellular region (Mus musculus)
I- [cytosol]
Organic anion transporters (Mus musculus)
Passive I- efflux mediated by SLC5A8 (Mus musculus)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Mus musculus)
I- [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Metabolism of amine-derived hormones (Rattus norvegicus)
Thyroxine biosynthesis (Rattus norvegicus)
Iodide is taken up by thyroid epithelial cells (Rattus norvegicus)
I- [cytosol]
Regulation of thyroid hormone activity (Rattus norvegicus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Rattus norvegicus)
I- [cytosol]
Thyroxine is deiodinated to triiodothyronine (Rattus norvegicus)
I- [cytosol]
Transport of small molecules (Rattus norvegicus)
Miscellaneous transport and binding events (Rattus norvegicus)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Rattus norvegicus)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Rattus norvegicus)
Multifunctional anion exchangers (Rattus norvegicus)
SLC26A4 transports I- from cytosol to extracellular region (Rattus norvegicus)
I- [cytosol]
Organic anion transporters (Rattus norvegicus)
Passive I- efflux mediated by SLC5A8 (Rattus norvegicus)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Rattus norvegicus)
I- [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Transport of inorganic cations/anions and amino acids/oligopeptides (Saccharomyces cerevisiae)
Multifunctional anion exchangers (Saccharomyces cerevisiae)
SLC26A4 transports I- from cytosol to extracellular region (Saccharomyces cerevisiae)
I- [cytosol]
Transport of small molecules (Schizosaccharomyces pombe)
SLC-mediated transmembrane transport (Schizosaccharomyces pombe)
Transport of inorganic cations/anions and amino acids/oligopeptides (Schizosaccharomyces pombe)
Multifunctional anion exchangers (Schizosaccharomyces pombe)
SLC26A4 transports I- from cytosol to extracellular region (Schizosaccharomyces pombe)
I- [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Metabolism of amine-derived hormones (Sus scrofa)
Thyroxine biosynthesis (Sus scrofa)
Iodide is taken up by thyroid epithelial cells (Sus scrofa)
I- [cytosol]
Regulation of thyroid hormone activity (Sus scrofa)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Sus scrofa)
I- [cytosol]
Thyroxine is deiodinated to triiodothyronine (Sus scrofa)
I- [cytosol]
Transport of small molecules (Sus scrofa)
Miscellaneous transport and binding events (Sus scrofa)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Sus scrofa)
I-, Cl- [cytosol]
I- [cytosol]
SLC-mediated transmembrane transport (Sus scrofa)
Transport of inorganic cations/anions and amino acids/oligopeptides (Sus scrofa)
Multifunctional anion exchangers (Sus scrofa)
SLC26A4 transports I- from cytosol to extracellular region (Sus scrofa)
I- [cytosol]
Organic anion transporters (Sus scrofa)
Passive I- efflux mediated by SLC5A8 (Sus scrofa)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Sus scrofa)
I- [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Metabolism of amine-derived hormones (Xenopus tropicalis)
Thyroxine biosynthesis (Xenopus tropicalis)
Iodide is taken up by thyroid epithelial cells (Xenopus tropicalis)
I- [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of inorganic cations/anions and amino acids/oligopeptides (Xenopus tropicalis)
Multifunctional anion exchangers (Xenopus tropicalis)
SLC26A4 transports I- from cytosol to extracellular region (Xenopus tropicalis)
I- [cytosol]
Organic anion transporters (Xenopus tropicalis)
Passive I- efflux mediated by SLC5A8 (Xenopus tropicalis)
I- [cytosol]
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Xenopus tropicalis)
I- [cytosol]
External Reference Information
External Reference
iodide [ChEBI:16382]
Participates
as an input of
SLC26A4 does not transport I- from cytosol to extracellular region (Homo sapiens)
Passive I- efflux mediated by SLC5A8 (Homo sapiens)
Passive I- efflux mediated by SLC5A8 (Mus musculus)
Passive I- efflux mediated by SLC5A8 (Rattus norvegicus)
Passive I- efflux mediated by SLC5A8 (Canis familiaris)
Passive I- efflux mediated by SLC5A8 (Bos taurus)
Passive I- efflux mediated by SLC5A8 (Sus scrofa)
Passive I- efflux mediated by SLC5A8 (Danio rerio)
Passive I- efflux mediated by SLC5A8 (Xenopus tropicalis)
Passive I- efflux mediated by SLC5A8 (Gallus gallus)
Passive I- efflux mediated by SLC5A8 (Drosophila melanogaster)
Passive I- efflux mediated by SLC5A8 (Caenorhabditis elegans)
SLC26A4 transports I- from cytosol to extracellular region (Homo sapiens)
SLC26A4 transports I- from cytosol to extracellular region (Mus musculus)
SLC26A4 transports I- from cytosol to extracellular region (Rattus norvegicus)
SLC26A4 transports I- from cytosol to extracellular region (Canis familiaris)
SLC26A4 transports I- from cytosol to extracellular region (Bos taurus)
SLC26A4 transports I- from cytosol to extracellular region (Sus scrofa)
SLC26A4 transports I- from cytosol to extracellular region (Xenopus tropicalis)
SLC26A4 transports I- from cytosol to extracellular region (Gallus gallus)
SLC26A4 transports I- from cytosol to extracellular region (Drosophila melanogaster)
SLC26A4 transports I- from cytosol to extracellular region (Caenorhabditis elegans)
SLC26A4 transports I- from cytosol to extracellular region (Dictyostelium discoideum)
SLC26A4 transports I- from cytosol to extracellular region (Schizosaccharomyces pombe)
SLC26A4 transports I- from cytosol to extracellular region (Saccharomyces cerevisiae)
as an output of
Thyroxine is deiodinated to triiodothyronine (Dictyostelium discoideum)
Thyroxine is deiodinated to triiodothyronine (Gallus gallus)
Thyroxine is deiodinated to triiodothyronine (Sus scrofa)
Thyroxine is deiodinated to triiodothyronine (Canis familiaris)
Thyroxine is deiodinated to triiodothyronine (Rattus norvegicus)
Thyroxine is deiodinated to triiodothyronine (Mus musculus)
Thyroxine is deiodinated to triiodothyronine (Homo sapiens)
Thyroxine is deiodinated to triiodothyronine (Bos taurus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Dictyostelium discoideum)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Sus scrofa)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Rattus norvegicus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Mus musculus)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Homo sapiens)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Bos taurus)
Iodide is taken up by thyroid epithelial cells (Caenorhabditis elegans)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Homo sapiens)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Mus musculus)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Rattus norvegicus)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Canis familiaris)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Bos taurus)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Sus scrofa)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Danio rerio)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Xenopus tropicalis)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Gallus gallus)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Drosophila melanogaster)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Caenorhabditis elegans)
Iodide is taken up by thyroid epithelial cells (Bos taurus)
Iodide is taken up by thyroid epithelial cells (Homo sapiens)
Iodide is taken up by thyroid epithelial cells (Mus musculus)
Iodide is taken up by thyroid epithelial cells (Rattus norvegicus)
Iodide is taken up by thyroid epithelial cells (Canis familiaris)
Iodide is taken up by thyroid epithelial cells (Sus scrofa)
Iodide is taken up by thyroid epithelial cells (Danio rerio)
Iodide is taken up by thyroid epithelial cells (Xenopus tropicalis)
Iodide is taken up by thyroid epithelial cells (Gallus gallus)
Iodide is taken up by thyroid epithelial cells (Drosophila melanogaster)
as a member of
I-, Cl- [cytosol]
Anions transported by Aquaporin-6 [cytosol]
Other forms of this molecule
I- [transport vesicle]
I- [extracellular region]
Cross References
COMPOUND
C00708
HMDB Metabolite
HMDB0012238
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