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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
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Species Comparison
Tissue Distribution
Diseases
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MAL [cytosol]
Stable Identifier
R-ALL-198498
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
(S)-Malate, (S)-malic acid, L-Malate, L-Apple acid, L-Malic acid, L-2-Hydroxybutanedioic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Sulfur amino acid metabolism (Bos taurus)
Degradation of cysteine and homocysteine (Bos taurus)
Sulfide oxidation to sulfate (Bos taurus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Bos taurus)
MAL [cytosol]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
MDH1 oxidizes MAL to OA (Bos taurus)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Bos taurus)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Bos taurus)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Bos taurus)
MAL [cytosol]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Fatty acyl-CoA biosynthesis (Bos taurus)
Transport of Citrate from Mitochondrial Matrix to cytosol (Bos taurus)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Bos taurus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Bos taurus)
Pyruvate metabolism (Bos taurus)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Bos taurus)
MAL [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Organic anion transporters (Bos taurus)
SLC25A10 mediates exchange of malate and phosphate (Bos taurus)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Bos taurus)
MAL [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Sulfur amino acid metabolism (Caenorhabditis elegans)
Degradation of cysteine and homocysteine (Caenorhabditis elegans)
Sulfide oxidation to sulfate (Caenorhabditis elegans)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Caenorhabditis elegans)
MAL [cytosol]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
MDH1 oxidizes MAL to OA (Caenorhabditis elegans)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Caenorhabditis elegans)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Caenorhabditis elegans)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Caenorhabditis elegans)
MAL [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Fatty acyl-CoA biosynthesis (Caenorhabditis elegans)
Transport of Citrate from Mitochondrial Matrix to cytosol (Caenorhabditis elegans)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism and Citric Acid (TCA) cycle (Caenorhabditis elegans)
Pyruvate metabolism (Caenorhabditis elegans)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Caenorhabditis elegans)
MAL [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of inorganic cations/anions and amino acids/oligopeptides (Caenorhabditis elegans)
Organic anion transporters (Caenorhabditis elegans)
SLC25A10 mediates exchange of malate and phosphate (Caenorhabditis elegans)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Caenorhabditis elegans)
MAL [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Sulfur amino acid metabolism (Canis familiaris)
Degradation of cysteine and homocysteine (Canis familiaris)
Sulfide oxidation to sulfate (Canis familiaris)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Canis familiaris)
MAL [cytosol]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
MDH1 oxidizes MAL to OA (Canis familiaris)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Canis familiaris)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Canis familiaris)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Canis familiaris)
MAL [cytosol]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Fatty acyl-CoA biosynthesis (Canis familiaris)
Transport of Citrate from Mitochondrial Matrix to cytosol (Canis familiaris)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Canis familiaris)
Pyruvate metabolism and Citric Acid (TCA) cycle (Canis familiaris)
Pyruvate metabolism (Canis familiaris)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Canis familiaris)
MAL [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Organic anion transporters (Canis familiaris)
SLC25A10 mediates exchange of malate and phosphate (Canis familiaris)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Canis familiaris)
MAL [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Sulfur amino acid metabolism (Danio rerio)
Degradation of cysteine and homocysteine (Danio rerio)
Sulfide oxidation to sulfate (Danio rerio)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Danio rerio)
MAL [cytosol]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
MDH1 oxidizes MAL to OA (Danio rerio)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Danio rerio)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Danio rerio)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Danio rerio)
MAL [cytosol]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Fatty acyl-CoA biosynthesis (Danio rerio)
Transport of Citrate from Mitochondrial Matrix to cytosol (Danio rerio)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Danio rerio)
Pyruvate metabolism and Citric Acid (TCA) cycle (Danio rerio)
Pyruvate metabolism (Danio rerio)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Danio rerio)
MAL [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of inorganic cations/anions and amino acids/oligopeptides (Danio rerio)
Organic anion transporters (Danio rerio)
SLC25A10 mediates exchange of malate and phosphate (Danio rerio)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Danio rerio)
MAL [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Sulfur amino acid metabolism (Dictyostelium discoideum)
Degradation of cysteine and homocysteine (Dictyostelium discoideum)
Sulfide oxidation to sulfate (Dictyostelium discoideum)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Dictyostelium discoideum)
MAL [cytosol]
Metabolism of carbohydrates (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
MDH1 oxidizes MAL to OA (Dictyostelium discoideum)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Dictyostelium discoideum)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Dictyostelium discoideum)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Dictyostelium discoideum)
MAL [cytosol]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of inorganic cations/anions and amino acids/oligopeptides (Dictyostelium discoideum)
Organic anion transporters (Dictyostelium discoideum)
SLC25A10 mediates exchange of malate and phosphate (Dictyostelium discoideum)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Dictyostelium discoideum)
MAL [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Sulfur amino acid metabolism (Drosophila melanogaster)
Degradation of cysteine and homocysteine (Drosophila melanogaster)
Sulfide oxidation to sulfate (Drosophila melanogaster)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Drosophila melanogaster)
MAL [cytosol]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
MDH1 oxidizes MAL to OA (Drosophila melanogaster)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Drosophila melanogaster)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Drosophila melanogaster)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Drosophila melanogaster)
MAL [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Fatty acyl-CoA biosynthesis (Drosophila melanogaster)
Transport of Citrate from Mitochondrial Matrix to cytosol (Drosophila melanogaster)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism and Citric Acid (TCA) cycle (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Drosophila melanogaster)
MAL [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Organic anion transporters (Drosophila melanogaster)
SLC25A10 mediates exchange of malate and phosphate (Drosophila melanogaster)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Drosophila melanogaster)
MAL [cytosol]
Metabolism (Gallus gallus)
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] (Gallus gallus)
MAL [cytosol]
malate + NAD+ <=> oxaloacetate + NADH + H+ (Gallus gallus)
MAL [cytosol]
malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] (Gallus gallus)
MAL [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Organic anion transporters (Gallus gallus)
SLC25A10 mediates exchange of malate and phosphate (Gallus gallus)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Gallus gallus)
MAL [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Sulfur amino acid metabolism (Homo sapiens)
Degradation of cysteine and homocysteine (Homo sapiens)
Sulfide oxidation to sulfate (Homo sapiens)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Homo sapiens)
MAL [cytosol]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
MDH1 oxidizes MAL to OA (Homo sapiens)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Homo sapiens)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Homo sapiens)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Homo sapiens)
MAL [cytosol]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Fatty acyl-CoA biosynthesis (Homo sapiens)
Transport of Citrate from Mitochondrial Matrix to cytosol (Homo sapiens)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Homo sapiens)
Pyruvate metabolism and Citric Acid (TCA) cycle (Homo sapiens)
Pyruvate metabolism (Homo sapiens)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Homo sapiens)
MAL [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Organic anion transporters (Homo sapiens)
SLC25A10 mediates exchange of malate and phosphate (Homo sapiens)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Homo sapiens)
MAL [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Sulfur amino acid metabolism (Mus musculus)
Degradation of cysteine and homocysteine (Mus musculus)
Sulfide oxidation to sulfate (Mus musculus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Mus musculus)
MAL [cytosol]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
MDH1 oxidizes MAL to OA (Mus musculus)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Mus musculus)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Mus musculus)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Mus musculus)
MAL [cytosol]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Fatty acyl-CoA biosynthesis (Mus musculus)
Transport of Citrate from Mitochondrial Matrix to cytosol (Mus musculus)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Mus musculus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Mus musculus)
Pyruvate metabolism (Mus musculus)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Mus musculus)
MAL [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Mus musculus)
Organic anion transporters (Mus musculus)
SLC25A10 mediates exchange of malate and phosphate (Mus musculus)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Mus musculus)
MAL [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Sulfur amino acid metabolism (Rattus norvegicus)
Degradation of cysteine and homocysteine (Rattus norvegicus)
Sulfide oxidation to sulfate (Rattus norvegicus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Rattus norvegicus)
MAL [cytosol]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
MDH1 oxidizes MAL to OA (Rattus norvegicus)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Rattus norvegicus)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Rattus norvegicus)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Rattus norvegicus)
MAL [cytosol]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Fatty acyl-CoA biosynthesis (Rattus norvegicus)
Transport of Citrate from Mitochondrial Matrix to cytosol (Rattus norvegicus)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Rattus norvegicus)
Pyruvate metabolism (Rattus norvegicus)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Rattus norvegicus)
MAL [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Rattus norvegicus)
Organic anion transporters (Rattus norvegicus)
SLC25A10 mediates exchange of malate and phosphate (Rattus norvegicus)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Rattus norvegicus)
MAL [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Sulfur amino acid metabolism (Saccharomyces cerevisiae)
Degradation of cysteine and homocysteine (Saccharomyces cerevisiae)
Sulfide oxidation to sulfate (Saccharomyces cerevisiae)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Saccharomyces cerevisiae)
MAL [cytosol]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
SLC25A10 mediates exchange of malate and phosphate (Saccharomyces cerevisiae)
MAL [cytosol]
Metabolism of lipids (Saccharomyces cerevisiae)
Fatty acid metabolism (Saccharomyces cerevisiae)
Fatty acyl-CoA biosynthesis (Saccharomyces cerevisiae)
Transport of Citrate from Mitochondrial Matrix to cytosol (Saccharomyces cerevisiae)
MAL [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Transport of inorganic cations/anions and amino acids/oligopeptides (Saccharomyces cerevisiae)
Organic anion transporters (Saccharomyces cerevisiae)
SLC25A10 mediates exchange of malate and phosphate (Saccharomyces cerevisiae)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Saccharomyces cerevisiae)
MAL [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Fatty acid metabolism (Schizosaccharomyces pombe)
Fatty acyl-CoA biosynthesis (Schizosaccharomyces pombe)
Transport of Citrate from Mitochondrial Matrix to cytosol (Schizosaccharomyces pombe)
MAL [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Sulfur amino acid metabolism (Sus scrofa)
Degradation of cysteine and homocysteine (Sus scrofa)
Sulfide oxidation to sulfate (Sus scrofa)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Sus scrofa)
MAL [cytosol]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
MDH1 oxidizes MAL to OA (Sus scrofa)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Sus scrofa)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Sus scrofa)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Sus scrofa)
MAL [cytosol]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Fatty acyl-CoA biosynthesis (Sus scrofa)
Transport of Citrate from Mitochondrial Matrix to cytosol (Sus scrofa)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Sus scrofa)
Pyruvate metabolism and Citric Acid (TCA) cycle (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Sus scrofa)
MAL [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of inorganic cations/anions and amino acids/oligopeptides (Sus scrofa)
Organic anion transporters (Sus scrofa)
SLC25A10 mediates exchange of malate and phosphate (Sus scrofa)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Sus scrofa)
MAL [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Sulfur amino acid metabolism (Xenopus tropicalis)
Degradation of cysteine and homocysteine (Xenopus tropicalis)
Sulfide oxidation to sulfate (Xenopus tropicalis)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Xenopus tropicalis)
MAL [cytosol]
Metabolism of carbohydrates (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Gluconeogenesis (Xenopus tropicalis)
MDH1 oxidizes MAL to OA (Xenopus tropicalis)
MAL [cytosol]
SLC25A10 mediates exchange of malate and phosphate (Xenopus tropicalis)
MAL [cytosol]
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Xenopus tropicalis)
MAL [cytosol]
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Xenopus tropicalis)
MAL [cytosol]
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Fatty acyl-CoA biosynthesis (Xenopus tropicalis)
Transport of Citrate from Mitochondrial Matrix to cytosol (Xenopus tropicalis)
MAL [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism and Citric Acid (TCA) cycle (Xenopus tropicalis)
Pyruvate metabolism (Xenopus tropicalis)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Xenopus tropicalis)
MAL [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of inorganic cations/anions and amino acids/oligopeptides (Xenopus tropicalis)
Organic anion transporters (Xenopus tropicalis)
SLC25A10 mediates exchange of malate and phosphate (Xenopus tropicalis)
MAL [cytosol]
Sulfate is exported to the cytosol in exchange for dicarboxylate (Xenopus tropicalis)
MAL [cytosol]
External Reference Information
External Reference
(S)-malate(2-) [ChEBI:15589]
Participates
as an input of
2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] (Gallus gallus)
malate + NAD+ <=> oxaloacetate + NADH + H+ (Gallus gallus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Saccharomyces cerevisiae)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Dictyostelium discoideum)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Caenorhabditis elegans)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Drosophila melanogaster)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Gallus gallus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Xenopus tropicalis)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Sus scrofa)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Bos taurus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Canis familiaris)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Rattus norvegicus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Mus musculus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Homo sapiens)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Danio rerio)
Transport of Citrate from Mitochondrial Matrix to cytosol (Saccharomyces cerevisiae)
Transport of Citrate from Mitochondrial Matrix to cytosol (Schizosaccharomyces pombe)
Transport of Citrate from Mitochondrial Matrix to cytosol (Caenorhabditis elegans)
Transport of Citrate from Mitochondrial Matrix to cytosol (Drosophila melanogaster)
Transport of Citrate from Mitochondrial Matrix to cytosol (Gallus gallus)
Transport of Citrate from Mitochondrial Matrix to cytosol (Xenopus tropicalis)
Transport of Citrate from Mitochondrial Matrix to cytosol (Danio rerio)
Transport of Citrate from Mitochondrial Matrix to cytosol (Sus scrofa)
Transport of Citrate from Mitochondrial Matrix to cytosol (Bos taurus)
Transport of Citrate from Mitochondrial Matrix to cytosol (Canis familiaris)
Transport of Citrate from Mitochondrial Matrix to cytosol (Rattus norvegicus)
Transport of Citrate from Mitochondrial Matrix to cytosol (Mus musculus)
Transport of Citrate from Mitochondrial Matrix to cytosol (Homo sapiens)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Caenorhabditis elegans)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Drosophila melanogaster)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Gallus gallus)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Xenopus tropicalis)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Danio rerio)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Sus scrofa)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Bos taurus)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Canis familiaris)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Rattus norvegicus)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Mus musculus)
ME1:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Homo sapiens)
MDH1 oxidizes MAL to OA (Dictyostelium discoideum)
MDH1 oxidizes MAL to OA (Caenorhabditis elegans)
MDH1 oxidizes MAL to OA (Drosophila melanogaster)
MDH1 oxidizes MAL to OA (Gallus gallus)
MDH1 oxidizes MAL to OA (Mus musculus)
MDH1 oxidizes MAL to OA (Homo sapiens)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Homo sapiens)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Mus musculus)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Rattus norvegicus)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Canis familiaris)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Bos taurus)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Sus scrofa)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Danio rerio)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Xenopus tropicalis)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Gallus gallus)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Drosophila melanogaster)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Caenorhabditis elegans)
SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Dictyostelium discoideum)
MDH1 oxidizes MAL to OA (Rattus norvegicus)
MDH1 oxidizes MAL to OA (Canis familiaris)
MDH1 oxidizes MAL to OA (Bos taurus)
MDH1 oxidizes MAL to OA (Sus scrofa)
MDH1 oxidizes MAL to OA (Danio rerio)
MDH1 oxidizes MAL to OA (Xenopus tropicalis)
as an output of
malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] (Gallus gallus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Mus musculus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Homo sapiens)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Rattus norvegicus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Canis familiaris)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Bos taurus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Sus scrofa)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Danio rerio)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Xenopus tropicalis)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Gallus gallus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Drosophila melanogaster)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Caenorhabditis elegans)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Dictyostelium discoideum)
SLC25A10 mediates exchange of malate and phosphate (Homo sapiens)
SLC25A10 mediates exchange of malate and phosphate (Mus musculus)
SLC25A10 mediates exchange of malate and phosphate (Rattus norvegicus)
SLC25A10 mediates exchange of malate and phosphate (Canis familiaris)
SLC25A10 mediates exchange of malate and phosphate (Bos taurus)
SLC25A10 mediates exchange of malate and phosphate (Sus scrofa)
SLC25A10 mediates exchange of malate and phosphate (Danio rerio)
SLC25A10 mediates exchange of malate and phosphate (Xenopus tropicalis)
SLC25A10 mediates exchange of malate and phosphate (Gallus gallus)
SLC25A10 mediates exchange of malate and phosphate (Drosophila melanogaster)
SLC25A10 mediates exchange of malate and phosphate (Caenorhabditis elegans)
SLC25A10 mediates exchange of malate and phosphate (Dictyostelium discoideum)
SLC25A10 mediates exchange of malate and phosphate (Saccharomyces cerevisiae)
Other forms of this molecule
MAL [mitochondrial matrix]
Cross References
AraCyc
MAL
CAS
97-67-6
,
6915-15-7
COMPOUND
C00149
PubChem Compound
5459792
ZINC
000000895074
KEGG Gene
C00149
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