Transport of Citrate from Mitochondrial Matrix to cytosol

Stable Identifier
R-HSA-75849
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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SLC25A1, in the inner mitochondrial membrane, mediates the exchange of mitochondrial citrate for cytosolic malate (Edvarson et al.2013, Gnoni et al.2009).

Literature References
PubMed ID Title Journal Year
19787704 The mitochondrial citrate carrier: metabolic role and regulation of its activity and expression

Gnoni, GV, Priore, P, Geelen, MJ, Siculella, L

IUBMB Life 2009
23393310 Agenesis of corpus callosum and optic nerve hypoplasia due to mutations in SLC25A1 encoding the mitochondrial citrate transporter

Edvardson, S, Porcelli, V, Jalas, C, Soiferman, D, Kellner, Y, Shaag, A, Korman, SH, Pierri, CL, Scarcia, P, Fraenkel, ND, Segel, R, Schechter, A, Frumkin, A, Pines, O, Saada, A, Palmieri, L, Elpeleg, O

J. Med. Genet. 2013
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
tricarboxylic acid transmembrane transporter activity of SLC25A1 [mitochondrial inner membrane]
Physical Entity
Activity
Orthologous Events
Created
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