Sulfate is exported to the cytosol in exchange for dicarboxylate

Stable Identifier
R-HSA-1614546
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial inner membrane, cytosol, mitochondrial matrix
ReviewStatus
5/5
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Sulfate is exported to the cytosol in exchange for dicarboxylate
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Sulfate leaves the mitochondrion with the help of the dicarboxylate carrier, via antiport with malate (Crompton et al. 1974, Fiemont et al. 1999)

Literature References
PubMed ID Title Journal Year
10585886 Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family

Fiermonte, G, Dolce, V, Arrigoni, R, Walker, JE, Runswick, MJ, Palmieri, F

Biochem J 1999
4441366 The transport of sulphate and sulphite in rat liver mitochondria

Capano, M, Quagliariello, E, Palmieri, F, Crompton, M

Biochem J 1974
Participants
Input
Output
Participates
as an event of
Catalyst Activity

dicarboxylic acid transmembrane transporter activity of SLC25A10 [mitochondrial inner membrane]

Physical Entity
SLC25A10 [mitochondrial inner membrane] (Homo sapiens)
Activity
dicarboxylic acid transmembrane transporter activity (GO:0005310)
Orthologous Events
Sulfate is exported to the cytosol in exchange for dicarboxylate (Bos taurus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Caenorhabditis elegans)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Canis familiaris)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Danio rerio)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Dictyostelium discoideum)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Drosophila melanogaster)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Gallus gallus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Mus musculus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Rattus norvegicus)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Saccharomyces cerevisiae)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Sus scrofa)
Sulfate is exported to the cytosol in exchange for dicarboxylate (Xenopus tropicalis)
Cross References
Rhea
Authored
Stephan, R  (2010-10-24)
Reviewed
D'Eustachio, P  (2011-10-13)
Created
Jassal, B  (2011-09-29)
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