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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
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DA [cytosol]
Stable Identifier
R-ALL-159362
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
dopamine
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase II - Conjugation of compounds (Bos taurus)
Cytosolic sulfonation of small molecules (Bos taurus)
SULT1A3,4 dimers sulfate DA to DAOS (Bos taurus)
DA [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Metabolism of amine-derived hormones (Bos taurus)
Catecholamine biosynthesis (Bos taurus)
Dopa is decarboxylated to dopamine (Bos taurus)
DA [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter clearance (Bos taurus)
Dopamine clearance from the synaptic cleft (Bos taurus)
Enzymatic degradation of Dopamine by monoamine oxidase (Bos taurus)
MAOA:FAD deaminates DA to DOPAC (Bos taurus)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Bos taurus)
COMT transfers Met to DA to form 3MT (Bos taurus)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Bos taurus)
DA [cytosol]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Bos taurus)
DA [cytosol]
Neurotransmitter release cycle (Bos taurus)
Dopamine Neurotransmitter Release Cycle (Bos taurus)
Loading of dopamine into synaptic veiscles (Bos taurus)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Bos taurus)
Loading of dopamine into synaptic veiscles (Bos taurus)
DA [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Na+/Cl- dependent neurotransmitter transporters (Bos taurus)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Bos taurus)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Bos taurus)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Bos taurus)
Organic cation transport (Bos taurus)
OCT1 transports organic cations into hepatic cells (Bos taurus)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Bos taurus)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Bos taurus)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Bos taurus)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Bos taurus)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Bos taurus)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Cytosolic sulfonation of small molecules (Caenorhabditis elegans)
SULT1A3,4 dimers sulfate DA to DAOS (Caenorhabditis elegans)
DA [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of amine-derived hormones (Caenorhabditis elegans)
Catecholamine biosynthesis (Caenorhabditis elegans)
Dopa is decarboxylated to dopamine (Caenorhabditis elegans)
DA [cytosol]
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter clearance (Caenorhabditis elegans)
Dopamine clearance from the synaptic cleft (Caenorhabditis elegans)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
DA [cytosol]
Neurotransmitter release cycle (Caenorhabditis elegans)
Dopamine Neurotransmitter Release Cycle (Caenorhabditis elegans)
Loading of dopamine into synaptic veiscles (Caenorhabditis elegans)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Caenorhabditis elegans)
Loading of dopamine into synaptic veiscles (Caenorhabditis elegans)
DA [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Na+/Cl- dependent neurotransmitter transporters (Caenorhabditis elegans)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Caenorhabditis elegans)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Caenorhabditis elegans)
Organic cation transport (Caenorhabditis elegans)
OCT1 transports organic cations into hepatic cells (Caenorhabditis elegans)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Caenorhabditis elegans)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Caenorhabditis elegans)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Caenorhabditis elegans)
OCT2 substrates [cytosol]
DA [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase II - Conjugation of compounds (Canis familiaris)
Cytosolic sulfonation of small molecules (Canis familiaris)
SULT1A3,4 dimers sulfate DA to DAOS (Canis familiaris)
DA [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Metabolism of amine-derived hormones (Canis familiaris)
Catecholamine biosynthesis (Canis familiaris)
Dopa is decarboxylated to dopamine (Canis familiaris)
DA [cytosol]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter clearance (Canis familiaris)
Dopamine clearance from the synaptic cleft (Canis familiaris)
Enzymatic degradation of Dopamine by monoamine oxidase (Canis familiaris)
MAOA:FAD deaminates DA to DOPAC (Canis familiaris)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Canis familiaris)
COMT transfers Met to DA to form 3MT (Canis familiaris)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Canis familiaris)
DA [cytosol]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Canis familiaris)
DA [cytosol]
Neurotransmitter release cycle (Canis familiaris)
Dopamine Neurotransmitter Release Cycle (Canis familiaris)
Loading of dopamine into synaptic veiscles (Canis familiaris)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Canis familiaris)
Loading of dopamine into synaptic veiscles (Canis familiaris)
DA [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Na+/Cl- dependent neurotransmitter transporters (Canis familiaris)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Canis familiaris)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Canis familiaris)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Canis familiaris)
Organic cation transport (Canis familiaris)
OCT2 mediates tubular secretion of organic cations in the kidney (Canis familiaris)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Canis familiaris)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Canis familiaris)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Canis familiaris)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Canis familiaris)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Cytosolic sulfonation of small molecules (Danio rerio)
SULT1A3,4 dimers sulfate DA to DAOS (Danio rerio)
DA [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of amine-derived hormones (Danio rerio)
Catecholamine biosynthesis (Danio rerio)
Dopa is decarboxylated to dopamine (Danio rerio)
DA [cytosol]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter clearance (Danio rerio)
Dopamine clearance from the synaptic cleft (Danio rerio)
Enzymatic degradation of Dopamine by monoamine oxidase (Danio rerio)
MAOA:FAD deaminates DA to DOPAC (Danio rerio)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Danio rerio)
COMT transfers Met to DA to form 3MT (Danio rerio)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Danio rerio)
DA [cytosol]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Danio rerio)
DA [cytosol]
Neurotransmitter release cycle (Danio rerio)
Dopamine Neurotransmitter Release Cycle (Danio rerio)
Loading of dopamine into synaptic veiscles (Danio rerio)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Danio rerio)
Loading of dopamine into synaptic veiscles (Danio rerio)
DA [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Na+/Cl- dependent neurotransmitter transporters (Danio rerio)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Danio rerio)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Danio rerio)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Danio rerio)
Organic cation transport (Danio rerio)
OCT1 transports organic cations into hepatic cells (Danio rerio)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Danio rerio)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Danio rerio)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Danio rerio)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Danio rerio)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Danio rerio)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Danio rerio)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Neuronal System (Dictyostelium discoideum)
Transmission across Chemical Synapses (Dictyostelium discoideum)
Neurotransmitter clearance (Dictyostelium discoideum)
Dopamine clearance from the synaptic cleft (Dictyostelium discoideum)
Enzymatic degradation of Dopamine by monoamine oxidase (Dictyostelium discoideum)
MAOA:FAD deaminates DA to DOPAC (Dictyostelium discoideum)
DA [cytosol]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of vitamins, nucleosides, and related molecules (Dictyostelium discoideum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Dictyostelium discoideum)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Dictyostelium discoideum)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Dictyostelium discoideum)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Metabolism of amine-derived hormones (Drosophila melanogaster)
Catecholamine biosynthesis (Drosophila melanogaster)
Dopa is decarboxylated to dopamine (Drosophila melanogaster)
DA [cytosol]
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter clearance (Drosophila melanogaster)
Dopamine clearance from the synaptic cleft (Drosophila melanogaster)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Drosophila melanogaster)
DA [cytosol]
Neurotransmitter release cycle (Drosophila melanogaster)
Dopamine Neurotransmitter Release Cycle (Drosophila melanogaster)
Loading of dopamine into synaptic veiscles (Drosophila melanogaster)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Drosophila melanogaster)
Loading of dopamine into synaptic veiscles (Drosophila melanogaster)
DA [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Na+/Cl- dependent neurotransmitter transporters (Drosophila melanogaster)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Drosophila melanogaster)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Drosophila melanogaster)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Drosophila melanogaster)
Organic cation transport (Drosophila melanogaster)
OCT1 transports organic cations into hepatic cells (Drosophila melanogaster)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Drosophila melanogaster)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Drosophila melanogaster)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Drosophila melanogaster)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Drosophila melanogaster)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Drosophila melanogaster)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Drosophila melanogaster)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase II - Conjugation of compounds (Gallus gallus)
Cytosolic sulfonation of small molecules (Gallus gallus)
SULT1A3,4 dimers sulfate DA to DAOS (Gallus gallus)
DA [cytosol]
Metabolism of amino acids and derivatives (Gallus gallus)
Metabolism of amine-derived hormones (Gallus gallus)
Catecholamine biosynthesis (Gallus gallus)
Dopa is decarboxylated to dopamine (Gallus gallus)
DA [cytosol]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter clearance (Gallus gallus)
Dopamine clearance from the synaptic cleft (Gallus gallus)
Enzymatic degradation of Dopamine by monoamine oxidase (Gallus gallus)
MAOA:FAD deaminates DA to DOPAC (Gallus gallus)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Gallus gallus)
COMT transfers Met to DA to form 3MT (Gallus gallus)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Gallus gallus)
DA [cytosol]
Neurotransmitter release cycle (Gallus gallus)
Dopamine Neurotransmitter Release Cycle (Gallus gallus)
Loading of dopamine into synaptic veiscles (Gallus gallus)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Gallus gallus)
Loading of dopamine into synaptic veiscles (Gallus gallus)
DA [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Na+/Cl- dependent neurotransmitter transporters (Gallus gallus)
VMAT1/2 can mediate the transport of biogenic amines (Gallus gallus)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Gallus gallus)
Organic cation transport (Gallus gallus)
OCT1 transports organic cations into hepatic cells (Gallus gallus)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Gallus gallus)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Gallus gallus)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Gallus gallus)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Gallus gallus)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Gallus gallus)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Gallus gallus)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
SULT1A3,4 dimers sulfate DA to DAOS (Homo sapiens)
DA [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of amine-derived hormones (Homo sapiens)
Catecholamine biosynthesis (Homo sapiens)
Dopa is decarboxylated to dopamine (Homo sapiens)
DA [cytosol]
Dopamine translocates to a secretory vesicle (Homo sapiens)
DA [cytosol]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter clearance (Homo sapiens)
Dopamine clearance from the synaptic cleft (Homo sapiens)
Enzymatic degradation of Dopamine by monoamine oxidase (Homo sapiens)
MAOA:FAD deaminates DA to DOPAC (Homo sapiens)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Homo sapiens)
COMT transfers Met to DA to form 3MT (Homo sapiens)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Homo sapiens)
DA [cytosol]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Homo sapiens)
DA [cytosol]
Neurotransmitter release cycle (Homo sapiens)
Dopamine Neurotransmitter Release Cycle (Homo sapiens)
Loading of dopamine into synaptic veiscles (Homo sapiens)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Homo sapiens)
Loading of dopamine into synaptic veiscles (Homo sapiens)
DA [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Na+/Cl- dependent neurotransmitter transporters (Homo sapiens)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Homo sapiens)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Homo sapiens)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic cation transport (Homo sapiens)
OCT1 transports organic cations into hepatic cells (Homo sapiens)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Homo sapiens)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Homo sapiens)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Homo sapiens)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Homo sapiens)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Homo sapiens)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase II - Conjugation of compounds (Mus musculus)
Cytosolic sulfonation of small molecules (Mus musculus)
SULT1A3,4 dimers sulfate DA to DAOS (Mus musculus)
DA [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Metabolism of amine-derived hormones (Mus musculus)
Catecholamine biosynthesis (Mus musculus)
Dopa is decarboxylated to dopamine (Mus musculus)
DA [cytosol]
Neuronal System (Mus musculus)
Transmission across Chemical Synapses (Mus musculus)
Neurotransmitter clearance (Mus musculus)
Dopamine clearance from the synaptic cleft (Mus musculus)
Enzymatic degradation of Dopamine by monoamine oxidase (Mus musculus)
MAOA:FAD deaminates DA to DOPAC (Mus musculus)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Mus musculus)
COMT transfers Met to DA to form 3MT (Mus musculus)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Mus musculus)
DA [cytosol]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Mus musculus)
DA [cytosol]
Neurotransmitter release cycle (Mus musculus)
Dopamine Neurotransmitter Release Cycle (Mus musculus)
Loading of dopamine into synaptic veiscles (Mus musculus)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Mus musculus)
Loading of dopamine into synaptic veiscles (Mus musculus)
DA [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Na+/Cl- dependent neurotransmitter transporters (Mus musculus)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Mus musculus)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Mus musculus)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Mus musculus)
Organic cation transport (Mus musculus)
OCT1 transports organic cations into hepatic cells (Mus musculus)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Mus musculus)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Mus musculus)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Mus musculus)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Mus musculus)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Mus musculus)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Mus musculus)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Neuronal System (Plasmodium falciparum)
Transmission across Chemical Synapses (Plasmodium falciparum)
Neurotransmitter clearance (Plasmodium falciparum)
Dopamine clearance from the synaptic cleft (Plasmodium falciparum)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Plasmodium falciparum)
DA [cytosol]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of bile salts and organic acids, metal ions and amine compounds (Plasmodium falciparum)
Na+/Cl- dependent neurotransmitter transporters (Plasmodium falciparum)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Plasmodium falciparum)
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Plasmodium falciparum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Plasmodium falciparum)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Plasmodium falciparum)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Plasmodium falciparum)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase II - Conjugation of compounds (Rattus norvegicus)
Cytosolic sulfonation of small molecules (Rattus norvegicus)
SULT1A3,4 dimers sulfate DA to DAOS (Rattus norvegicus)
DA [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Metabolism of amine-derived hormones (Rattus norvegicus)
Catecholamine biosynthesis (Rattus norvegicus)
Dopa is decarboxylated to dopamine (Rattus norvegicus)
DA [cytosol]
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter clearance (Rattus norvegicus)
Dopamine clearance from the synaptic cleft (Rattus norvegicus)
Enzymatic degradation of Dopamine by monoamine oxidase (Rattus norvegicus)
MAOA:FAD deaminates DA to DOPAC (Rattus norvegicus)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Rattus norvegicus)
COMT transfers Met to DA to form 3MT (Rattus norvegicus)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Rattus norvegicus)
DA [cytosol]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Rattus norvegicus)
DA [cytosol]
Neurotransmitter release cycle (Rattus norvegicus)
Dopamine Neurotransmitter Release Cycle (Rattus norvegicus)
Loading of dopamine into synaptic veiscles (Rattus norvegicus)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Rattus norvegicus)
Loading of dopamine into synaptic veiscles (Rattus norvegicus)
DA [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Na+/Cl- dependent neurotransmitter transporters (Rattus norvegicus)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Rattus norvegicus)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Rattus norvegicus)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Rattus norvegicus)
Organic cation transport (Rattus norvegicus)
OCT1 transports organic cations into hepatic cells (Rattus norvegicus)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Rattus norvegicus)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Rattus norvegicus)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Rattus norvegicus)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Rattus norvegicus)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Rattus norvegicus)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Rattus norvegicus)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Neuronal System (Schizosaccharomyces pombe)
Transmission across Chemical Synapses (Schizosaccharomyces pombe)
Neurotransmitter clearance (Schizosaccharomyces pombe)
Dopamine clearance from the synaptic cleft (Schizosaccharomyces pombe)
Enzymatic degradation of dopamine by COMT (Schizosaccharomyces pombe)
COMT transfers Met to DA to form 3MT (Schizosaccharomyces pombe)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Schizosaccharomyces pombe)
DA [cytosol]
Neurotransmitter release cycle (Schizosaccharomyces pombe)
Dopamine Neurotransmitter Release Cycle (Schizosaccharomyces pombe)
Loading of dopamine into synaptic veiscles (Schizosaccharomyces pombe)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Schizosaccharomyces pombe)
Loading of dopamine into synaptic veiscles (Schizosaccharomyces pombe)
DA [cytosol]
Transport of small molecules (Schizosaccharomyces pombe)
SLC-mediated transmembrane transport (Schizosaccharomyces pombe)
Transport of bile salts and organic acids, metal ions and amine compounds (Schizosaccharomyces pombe)
Na+/Cl- dependent neurotransmitter transporters (Schizosaccharomyces pombe)
VMAT1/2 can mediate the transport of biogenic amines (Schizosaccharomyces pombe)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase II - Conjugation of compounds (Sus scrofa)
Cytosolic sulfonation of small molecules (Sus scrofa)
SULT1A3,4 dimers sulfate DA to DAOS (Sus scrofa)
DA [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Metabolism of amine-derived hormones (Sus scrofa)
Catecholamine biosynthesis (Sus scrofa)
Dopa is decarboxylated to dopamine (Sus scrofa)
DA [cytosol]
Neuronal System (Sus scrofa)
Transmission across Chemical Synapses (Sus scrofa)
Neurotransmitter clearance (Sus scrofa)
Dopamine clearance from the synaptic cleft (Sus scrofa)
Enzymatic degradation of Dopamine by monoamine oxidase (Sus scrofa)
MAOA:FAD deaminates DA to DOPAC (Sus scrofa)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Sus scrofa)
COMT transfers Met to DA to form 3MT (Sus scrofa)
DA [cytosol]
LRTOMT transfers Met to DA, forming 3MT (Sus scrofa)
DA [cytosol]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Sus scrofa)
DA [cytosol]
Neurotransmitter release cycle (Sus scrofa)
Dopamine Neurotransmitter Release Cycle (Sus scrofa)
Loading of dopamine into synaptic veiscles (Sus scrofa)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Sus scrofa)
Loading of dopamine into synaptic veiscles (Sus scrofa)
DA [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Na+/Cl- dependent neurotransmitter transporters (Sus scrofa)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Sus scrofa)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Sus scrofa)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Sus scrofa)
Organic cation transport (Sus scrofa)
OCT1 transports organic cations into hepatic cells (Sus scrofa)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Sus scrofa)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Sus scrofa)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Sus scrofa)
OCT2 substrates [cytosol]
DA [cytosol]
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Sus scrofa)
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Sus scrofa)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Sus scrofa)
ligands of SLC29A4 [cytosol]
DA [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase II - Conjugation of compounds (Xenopus tropicalis)
Cytosolic sulfonation of small molecules (Xenopus tropicalis)
SULT1A3,4 dimers sulfate DA to DAOS (Xenopus tropicalis)
DA [cytosol]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Metabolism of amine-derived hormones (Xenopus tropicalis)
Catecholamine biosynthesis (Xenopus tropicalis)
Dopa is decarboxylated to dopamine (Xenopus tropicalis)
DA [cytosol]
Neuronal System (Xenopus tropicalis)
Transmission across Chemical Synapses (Xenopus tropicalis)
Neurotransmitter clearance (Xenopus tropicalis)
Dopamine clearance from the synaptic cleft (Xenopus tropicalis)
Enzymatic degradation of Dopamine by monoamine oxidase (Xenopus tropicalis)
MAOA:FAD deaminates DA to DOPAC (Xenopus tropicalis)
DA [cytosol]
Enzymatic degradation of dopamine by COMT (Xenopus tropicalis)
COMT transfers Met to DA to form 3MT (Xenopus tropicalis)
DA [cytosol]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Xenopus tropicalis)
DA [cytosol]
Neurotransmitter release cycle (Xenopus tropicalis)
Dopamine Neurotransmitter Release Cycle (Xenopus tropicalis)
Loading of dopamine into synaptic veiscles (Xenopus tropicalis)
DA [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Xenopus tropicalis)
Loading of dopamine into synaptic veiscles (Xenopus tropicalis)
DA [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Na+/Cl- dependent neurotransmitter transporters (Xenopus tropicalis)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Xenopus tropicalis)
DA [cytosol]
VMAT1/2 can mediate the transport of biogenic amines (Xenopus tropicalis)
Biogenic amines transported by VMAT1/2 [cytosol]
DA [cytosol]
Organic cation/anion/zwitterion transport (Xenopus tropicalis)
Organic cation transport (Xenopus tropicalis)
OCT1 transports organic cations into hepatic cells (Xenopus tropicalis)
OCT1 substrates [cytosol]
DA [cytosol]
OCT1 transports organic cations out of hepatic cells (Xenopus tropicalis)
OCT1 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular secretion of organic cations in the kidney (Xenopus tropicalis)
OCT2 substrates [cytosol]
DA [cytosol]
OCT2 mediates tubular uptake of organic cations in the kidney (Xenopus tropicalis)
OCT2 substrates [cytosol]
DA [cytosol]
External Reference Information
External Reference
dopaminium(1+) [ChEBI:59905]
Participates
as an input of
SULT1A3,4 dimers sulfate DA to DAOS (Caenorhabditis elegans)
SULT1A3,4 dimers sulfate DA to DAOS (Gallus gallus)
SULT1A3,4 dimers sulfate DA to DAOS (Xenopus tropicalis)
SULT1A3,4 dimers sulfate DA to DAOS (Danio rerio)
SULT1A3,4 dimers sulfate DA to DAOS (Sus scrofa)
SULT1A3,4 dimers sulfate DA to DAOS (Bos taurus)
SULT1A3,4 dimers sulfate DA to DAOS (Canis familiaris)
SULT1A3,4 dimers sulfate DA to DAOS (Rattus norvegicus)
SULT1A3,4 dimers sulfate DA to DAOS (Mus musculus)
SULT1A3,4 dimers sulfate DA to DAOS (Homo sapiens)
MAOA:FAD deaminates DA to DOPAC (Gallus gallus)
MAOA:FAD deaminates DA to DOPAC (Xenopus tropicalis)
MAOA:FAD deaminates DA to DOPAC (Danio rerio)
MAOA:FAD deaminates DA to DOPAC (Sus scrofa)
MAOA:FAD deaminates DA to DOPAC (Bos taurus)
MAOA:FAD deaminates DA to DOPAC (Canis familiaris)
MAOA:FAD deaminates DA to DOPAC (Rattus norvegicus)
MAOA:FAD deaminates DA to DOPAC (Mus musculus)
MAOA:FAD deaminates DA to DOPAC (Homo sapiens)
MAOA:FAD deaminates DA to DOPAC (Dictyostelium discoideum)
Dopamine translocates to a secretory vesicle (Homo sapiens)
Loading of dopamine into synaptic veiscles (Homo sapiens)
Loading of dopamine into synaptic veiscles (Mus musculus)
Loading of dopamine into synaptic veiscles (Rattus norvegicus)
Loading of dopamine into synaptic veiscles (Canis familiaris)
Loading of dopamine into synaptic veiscles (Bos taurus)
Loading of dopamine into synaptic veiscles (Sus scrofa)
Loading of dopamine into synaptic veiscles (Danio rerio)
Loading of dopamine into synaptic veiscles (Xenopus tropicalis)
Loading of dopamine into synaptic veiscles (Gallus gallus)
Loading of dopamine into synaptic veiscles (Drosophila melanogaster)
Loading of dopamine into synaptic veiscles (Caenorhabditis elegans)
Loading of dopamine into synaptic veiscles (Schizosaccharomyces pombe)
LRTOMT transfers Met to DA, forming 3MT (Homo sapiens)
LRTOMT transfers Met to DA, forming 3MT (Mus musculus)
LRTOMT transfers Met to DA, forming 3MT (Rattus norvegicus)
LRTOMT transfers Met to DA, forming 3MT (Canis familiaris)
LRTOMT transfers Met to DA, forming 3MT (Bos taurus)
LRTOMT transfers Met to DA, forming 3MT (Sus scrofa)
LRTOMT transfers Met to DA, forming 3MT (Danio rerio)
LRTOMT transfers Met to DA, forming 3MT (Gallus gallus)
LRTOMT transfers Met to DA, forming 3MT (Schizosaccharomyces pombe)
COMT transfers Met to DA to form 3MT (Homo sapiens)
COMT transfers Met to DA to form 3MT (Mus musculus)
COMT transfers Met to DA to form 3MT (Rattus norvegicus)
COMT transfers Met to DA to form 3MT (Canis familiaris)
COMT transfers Met to DA to form 3MT (Bos taurus)
COMT transfers Met to DA to form 3MT (Sus scrofa)
COMT transfers Met to DA to form 3MT (Danio rerio)
COMT transfers Met to DA to form 3MT (Xenopus tropicalis)
COMT transfers Met to DA to form 3MT (Gallus gallus)
COMT transfers Met to DA to form 3MT (Schizosaccharomyces pombe)
as an output of
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Plasmodium falciparum)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Drosophila melanogaster)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Xenopus tropicalis)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Danio rerio)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Sus scrofa)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Bos taurus)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Canis familiaris)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Rattus norvegicus)
Dopa is decarboxylated to dopamine (Homo sapiens)
Dopa is decarboxylated to dopamine (Mus musculus)
Dopa is decarboxylated to dopamine (Rattus norvegicus)
Dopa is decarboxylated to dopamine (Canis familiaris)
Dopa is decarboxylated to dopamine (Bos taurus)
Dopa is decarboxylated to dopamine (Sus scrofa)
Dopa is decarboxylated to dopamine (Danio rerio)
Dopa is decarboxylated to dopamine (Xenopus tropicalis)
Dopa is decarboxylated to dopamine (Gallus gallus)
Dopa is decarboxylated to dopamine (Drosophila melanogaster)
Dopa is decarboxylated to dopamine (Caenorhabditis elegans)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Homo sapiens)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Mus musculus)
as a member of
ligands of SLC29A4 [cytosol]
OCT2 substrates [cytosol]
OCT1 substrates [cytosol]
Biogenic amines transported by VMAT1/2 [cytosol]
Other forms of this molecule
DA [clathrin-sculpted monoamine transport vesicle lumen]
DA [extracellular region]
Cross References
COMPOUND
C03758
ZINC
000000033882
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