MAOA:FAD deaminates DA to DOPAC

Stable Identifier
R-HSA-379382
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC)
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Dopamine (DA) is oxidatively deaminated to 3,4-dihydroxyphenylacetic acid (DOPAC) by monoamine oxidase A (MAOA), bound to its cofactor FAD (O'Caroll et al.1983).

Literature References
PubMed ID Title Journal Year
6408492 The deamination of dopamine by human brain monoamine oxidase. Specificity for the two enzyme forms in seven brain regions

Tipton, KF, O'Carroll, AM, Phillips, JP, Tobbia, I, Fowler, CJ

Naunyn Schmiedebergs Arch Pharmacol 1983
Participants
Participates
Catalyst Activity

primary amine oxidase activity of MAOA:FAD [mitochondrial outer membrane]

Orthologous Events
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