Reactome | TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane]

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TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] Show undefined attributes

compartment	[Compartment:74700] endosome membrane
componentOf	[Complex:R-HSA-975174] K63-linked poly-Ub-IRF7:TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9. [endosome membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-975188] TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation - Homo sapiens
created	[InstanceEdit:975168] Shamovsky, V, 2010-09-22
dbId	975148
displayName	TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane]
hasComponent	[Complex:R-HSA-975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] 4 × [EntityWithAccessionedSequence:R-HSA-450272] TRAF6 [endosome membrane]
inDisease	false
isChimeric	false
maxDepth	9
modified	[InstanceEdit:9768151] Shamovsky, Veronica, 2022-03-04
name	TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9
producedByEvent	[Reaction:R-HSA-975106] Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus [Species:164493] Human immunodeficiency virus 1 [Species:9031716] Influenza A virus [Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-975148
updateTrackers	[UpdateTracker:9871253] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9873321] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v42:[updateContainedComponent] [UpdateTracker:9903443] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9901609] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9901388] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v73:[updateContainedComponent] [UpdateTracker:9953820] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9869955] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9870390] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9902844] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v79:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9871253] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9873321] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v42:[updateContainedComponent] [UpdateTracker:9903443] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9901609] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9901388] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v73:[updateContainedComponent] [UpdateTracker:9953820] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9869955] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9870390] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9902844] Update Tracker - [Complex:975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v79:[updateContainedComponent]
(hasComponent)	[Complex:R-HSA-975174] K63-linked poly-Ub-IRF7:TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9. [endosome membrane] [Complex:R-HSA-975131] IRF7:TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane]
(input)	[Reaction:R-HSA-975188] TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation
(output)	[Reaction:R-HSA-975106] Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation

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