Reactome | p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane]

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p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] Show undefined attributes

compartment	[Compartment:74700] endosome membrane
componentOf	[Complex:R-HSA-975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - Homo sapiens
created	[InstanceEdit:975168] Shamovsky, V, 2010-09-22
dbId	975107
displayName	p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane]
hasComponent	4 × [EntityWithAccessionedSequence:R-HSA-975157] p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] [Complex:R-HSA-975159] p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 receptor [endosome membrane]
inDisease	false
literatureReference	[LiteratureReference:975472] Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction
maxDepth	8
modified	[InstanceEdit:9768151] Shamovsky, Veronica, 2022-03-04
name	p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9
producedByEvent	[Reaction:R-HSA-975125] Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus [Species:164493] Human immunodeficiency virus 1 [Species:9031716] Influenza A virus [Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-975107
updateTrackers	[UpdateTracker:9869953] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9902849] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v79:[updateContainedComponent] [UpdateTracker:9870465] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9953831] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9871165] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9901579] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9903852] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9873244] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9901250] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v73:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9869953] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9902849] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v79:[updateContainedComponent] [UpdateTracker:9870465] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9953831] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9871165] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9901579] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9903852] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9873244] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9901250] Update Tracker - [Complex:975107] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane] - v73:[updateContainedComponent]
(output)	[Reaction:R-HSA-975125] Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9
(hasComponent)	[Complex:R-HSA-975148] TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane]

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