Reactome | p16INK4A LoF mutants (CDK4/6) [cytosol]

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p16INK4A LoF mutants (CDK4/6) [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-9630795] p16INK4A mutants do not bind CDK4,CDK6 - Homo sapiens
created	[InstanceEdit:9630803] Orlic-Milacic, Marija, 2018-12-03
dbId	9630804
disease	[Disease:1500689] cancer
displayName	p16INK4A LoF mutants (CDK4/6) [cytosol]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-9630855] p16INK4A A20E [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9630861] p16INK4A A20T [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631027] p16INK4A P114S [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631034] p16INK4A P114T [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631043] p16INK4A P114H [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631046] p16INK4A P114R [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631263] p16INK4A G101V [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631126] p16INK4A V126A [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631120] p16INK4A V126F [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631130] p16INK4A V126I [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632287] p16INK4A P81S [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632294] p16INK4A P81R [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632293] p16INK4A P81H [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632486] p16INK4A D84A [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632587] p16INK4A E120* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648382] p16INK4A E10* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648383] p16INK4A S12* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648389] p16INK4A C72* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648390] p16INK4A E119* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648392] p16INK4A E26* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648387] p16INK4A E27* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648393] p16INK4A E33* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648396] p16INK4A E61* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648397] p16INK4A E69* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648388] p16INK4A P75* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648394] p16INK4A Q50* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648395] p16INK4A W15* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648653] p16INK4A A36fs17 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648652] p16INK4A G23fs3 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648663] p16INK4A L16fs9 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648664] p16INK4A Y44 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648659] p16INK4A L37fs16 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648647] p16INK4A N39fs14 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648651] p16INK4A S7fs8 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648655] p16INK4A T18fs15 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648656] p16INK4A T18fs8 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9648654] p16INK4A W15fs1 [cytosol] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-9630805] p16INK4A A20P [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9630911] p16INK4A M53I [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9630916] p16INK4A P114L [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631257] p16INK4A G101W [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9631055] p16INK4A V126D [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632280] p16INK4A P81L [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632275] p16INK4A P81T [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632335] p16INK4A R87P [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632461] p16INK4A D84G [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632465] p16INK4A D84V [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632489] p16INK4A D84H [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632483] p16INK4A D84N [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632478] p16INK4A D84Y [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632588] p16INK4A E88* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632582] p16INK4A R58* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632586] p16INK4A R80* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9632585] p16INK4A W110* [cytosol] - Homo sapiens
inDisease	true
modified	[InstanceEdit:9853063] D'Eustachio, Peter, 2023-11-09
name	p16INK4A LoF mutants (CDK4/6)
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9630804

Referrals

(input)	[FailedReaction:R-HSA-9630795] p16INK4A mutants do not bind CDK4,CDK6
(diseaseEntity)	[EntityFunctionalStatus:9630819] loss_of_function of p16INK4A LoF mutants (CDK4/6) [cytosol]

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