Reactome | p16INK4A R58* [cytosol]

Schema > EntityWithAccessionedSequence > Entries

p16INK4A R58* [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9632581] Orlic-Milacic, Marija, 2018-12-19
crossReference	[DatabaseIdentifier:9632614] COSMIC:COSV58683779 [DatabaseIdentifier:9632615] COSMIC:COSM53073 [DatabaseIdentifier:9632610] COSMIC:COSV58687698 [DatabaseIdentifier:9632620] COSMIC:COSV58682666
dbId	9632582
disease	[Disease:1500689] cancer [Disease:1614289] melanoma [Disease:2328001] skin squamous cell carcinoma [Disease:9632611] chordoma [Disease:2328201] myeloma [Disease:1500575] ovarian cancer [Disease:9630864] pancreatic ductal adenocarcinoma [Disease:2328199] basal cell carcinoma [Disease:1500687] stomach cancer [Disease:1655468] thymus cancer [Disease:1493885] bladder carcinoma [Disease:1500576] breast cancer [Disease:1614672] cervical cancer [Disease:9631134] cervical squamous cell carcinoma [Disease:9632617] diffuse large B-cell lymphoma [Disease:2317476] acute lymphocytic leukemia [Disease:2327993] hepatocellular carcinoma [Disease:8853117] lung adenocarcinoma [Disease:1500699] lung cancer [Disease:1981182] lung squamous cell carcinoma [Disease:1247848] non-small cell lung carcinoma [Disease:9632204] Barrett's esophagus [Disease:9632339] esophagus adenocarcinoma [Disease:9630862] esophagus squamous cell carcinoma [Disease:2327994] penis carcinoma [Disease:1655480] salivary gland cancer [Disease:9632211] epidermal appendage tumor [Disease:9632609] fibrosarcoma [Disease:9632612] fibrous histiocytoma [Disease:9630843] oral squamous cell carcinoma [Disease:9632618] nasopharynx carcinoma [Disease:2328083] larynx cancer [Disease:9632616] oral mucosa leukoplakia [Disease:1248679] head and neck squamous cell carcinoma [Disease:9632101] vulva squamous cell carcinoma [Disease:9632619] sebaceous carcinoma
displayName	p16INK4A R58* [cytosol]
endCoordinate	57
hasModifiedResidue	[NonsenseMutation:9649365] Nonsense mutation at L-arginine 58
inDisease	true
literatureReference	[LiteratureReference:9632578] CDKN2A/p16 is inactivated in most melanoma cell lines
memberOf	[CandidateSet:R-HSA-9630804] p16INK4A LoF mutants (CDK4/6) [cytosol] - Homo sapiens
modified	[InstanceEdit:9649386] Orlic-Milacic, Marija, 2019-06-13
name	p16INK4A R58* p16INK4A R58TER p16INK4A Arg58TER p16INK4A Arg58* CDKN2A R58TER CDKN2A Arg58TER CDKN2A R58* CDKN2A Arg58*
referenceEntity	[ReferenceGeneProduct:87039] UniProt:P42771 CDKN2A
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9632582
startCoordinate	1

Referrals

(hasMember)

[CandidateSet:R-HSA-9630804] p16INK4A LoF mutants (CDK4/6) [cytosol]

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