Reactome | p16INK4A D84G [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9632464] Orlic-Milacic, Marija, 2018-12-18
crossReference	[DatabaseIdentifier:12021315] Mondo:0005184 [DatabaseIdentifier:9632462] COSMIC:COSV58688961
dbId	9632461
disease	[Disease:1500689] cancer [Disease:2328001] skin squamous cell carcinoma [Disease:9630864] pancreatic ductal adenocarcinoma [Disease:1500575] ovarian cancer [Disease:9632339] esophagus adenocarcinoma [Disease:1981182] lung squamous cell carcinoma [Disease:2327993] hepatocellular carcinoma [Disease:1500576] breast cancer
displayName	p16INK4A D84G [cytosol]
endCoordinate	156
hasModifiedResidue	[ReplacedResidue:9632463] L-aspartic acid 84 replaced with glycine
inDisease	true
literatureReference	[LiteratureReference:9632347] Biologic and biochemical analyses of p16(INK4a) mutations from primary tumors
maxDepth	1
memberOf	[CandidateSet:R-HSA-9630804] p16INK4A LoF mutants (CDK4/6) [cytosol] - Homo sapiens
modified	[InstanceEdit:9645190] Orlic-Milacic, Marija, 2019-05-06
name	p16INK4A D84G p16INK4A Asp84Gly CDKN2A D84G CDKN2A Asp84Gly
referenceEntity	[ReferenceGeneProduct:uniprot:P42771] UniProt:P42771 CDKN2A
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9632461
startCoordinate	1

(hasMember)

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