Reactome | p16INK4A E88* [cytosol]

Schema > EntityWithAccessionedSequence > Entries

p16INK4A E88* [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9632589] Orlic-Milacic, Marija, 2018-12-19
crossReference	[DatabaseIdentifier:9632638] COSMIC:COSM144161 [DatabaseIdentifier:9632640] COSMIC:COSV58683071
dbId	9632588
disease	[Disease:1500689] cancer [Disease:1614289] melanoma [Disease:9630864] pancreatic ductal adenocarcinoma [Disease:2328001] skin squamous cell carcinoma [Disease:1996318] astrocytoma [Disease:2327989] bile duct carcinoma [Disease:2362392] brain meningioma [Disease:9606370] chondrosarcoma [Disease:2327993] hepatocellular carcinoma [Disease:1500699] lung cancer [Disease:1981182] lung squamous cell carcinoma [Disease:9632204] Barrett's esophagus [Disease:9630862] esophagus squamous cell carcinoma [Disease:9632612] fibrous histiocytoma [Disease:1248679] head and neck squamous cell carcinoma [Disease:9632616] oral mucosa leukoplakia [Disease:2328083] larynx cancer [Disease:9630843] oral squamous cell carcinoma [Disease:9630850] pharynx squamous cell carcinoma
displayName	p16INK4A E88* [cytosol]
endCoordinate	87
hasModifiedResidue	[NonsenseMutation:9649369] Nonsense mutation at L-glutamic acid 88
inDisease	true
literatureReference	[LiteratureReference:9632578] CDKN2A/p16 is inactivated in most melanoma cell lines
memberOf	[CandidateSet:R-HSA-9630804] p16INK4A LoF mutants (CDK4/6) [cytosol] - Homo sapiens
modified	[InstanceEdit:9649386] Orlic-Milacic, Marija, 2019-06-13
name	p16INK4A E88* p16INK4A E88TER p16INK4A Glu88TER p16INK4A Glu88* CDKN2A E88TER CDKN2A Glu88TER CDKN2A E88* CDKN2A Glu88*
referenceEntity	[ReferenceGeneProduct:87039] UniProt:P42771 CDKN2A
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9632588
startCoordinate	1

Referrals

(hasMember)

[CandidateSet:R-HSA-9630804] p16INK4A LoF mutants (CDK4/6) [cytosol]

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