EGR2 and SOX10 bind the MAG gene

Stable Identifier
R-HSA-9616116
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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EGR2 and SOX10 bind the MAG gene
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EGR2 and SOX10 bind to elements in the MAG gene to promote expression during myelination in the peripheral and central nervous system (Jones et al, 2007; Jang et al, 2006; LeBlanc et al, 2007).

Literature References
PubMed ID Title Journal Year
18634568 Interactions of Sox10 and Egr2 in myelin gene regulation

Nagarajan, R, Jones, EA, Mager, GM, Ward, RM, Chang, LW, Svaren, J, Jang, SW, Srinivasan, R, Gokey, NG

Neuron Glia Biol. 2007
16923174 In vivo detection of Egr2 binding to target genes during peripheral nerve myelination

Wrabetz, L, Svaren, J, Leblanc, SE, Jang, SW, Roopra, A

J. Neurochem. 2006
17325040 Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10

Ward, RM, Svaren, J, Leblanc, SE

Mol. Cell. Biol. 2007
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Authored
Rothfels, K  (2019-08-16)
Reviewed
Aletta, J M  (2020-01-17)
Created
Rothfels, K  (2018-08-09)
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