Reactome | Interaction of MEKK1 with TRAF6

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Interaction of MEKK1 with TRAF6 Show undefined attributes

authored	[InstanceEdit:918228] Garapati, P V, 2010-08-02
category	binding
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:933535] Garapati, P V, 2010-08-16
dbId	933528
displayName	Interaction of MEKK1 with TRAF6
edited	[InstanceEdit:918228] Garapati, P V, 2010-08-02
eventOf	[Pathway:R-HSA-933542] TRAF6 mediated NF-kB activation - Homo sapiens
followingEvent	[Reaction:R-HSA-933530] Activation of IKK by MEKK1 - Homo sapiens
inferredFrom	[Reaction:R-MMU-933534] Interaction of MEKK1 with TRAF6 - Mus musculus
input	[Complex:R-HSA-933467] dsRNA:DDX58/dsRNA:IFIH1:MAVS:TRAF2/TRAF6 [mitochondrial outer membrane] [EntityWithAccessionedSequence:R-HSA-166866] MAP3K1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9835829] Shamovsky, Veronica, 2023-05-18
name	Interaction of MEKK1 with TRAF6
orthologousEvent	[Reaction:R-GGA-1227778] MEKK1 binds TRAF6 - Gallus gallus
output	[Complex:R-HSA-933482] dsRNA:DDX58/IFIH1:MAVS:TRAF2/TRAF6:MEKK1 [mitochondrial outer membrane]
precedingEvent	[Reaction:R-HSA-918230] Recruitment of TRAF6/TRAF2 to MAVS - Homo sapiens
relatedSpecies	[Species:5621375] Hepatitis C Virus [Species:9013948] Measles virus [Species:5617433] Rotavirus [Species:9031716] Influenza A virus [Species:9717528] Human respiratory syncytial virus A
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:990527] Kawai, T, Akira, S, 2010-10-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-933528
summation	[Summation:933434] TRAF6 requires MEKK1 (MAP3K1) to activate NF-kB and MEKK1 ma...
updateTrackers	[UpdateTracker:9779617] Update Tracker - [Reaction:933528] Interaction of MEKK1 with TRAF6 - v65:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9779617] Update Tracker - [Reaction:933528] Interaction of MEKK1 with TRAF6 - v65:[modifyText]
(hasEvent)	[Pathway:R-HSA-933542] TRAF6 mediated NF-kB activation
(precedingEvent)	[Reaction:R-HSA-933530] Activation of IKK by MEKK1
(inferredTo)	[Reaction:R-MMU-933534] Interaction of MEKK1 with TRAF6

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