Interaction of MEKK1 with TRAF6

Stable Identifier
R-HSA-933528
Type
Reaction
Species
Homo sapiens
Related Species
Influenza A virus, Rotavirus, Hepatitis C Virus, Measles virus
Compartment
cytosol, mitochondrial outer membrane
Locations in the PathwayBrowser
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Interaction of MEKK1 with TRAF6
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TRAF6 requires MEKK1 (MAP3K1) to activate NF-kB and MEKK1 may interact with TRAF6, which in turn contributes to the activation of IKK and MAPKK, leading to the activation of NF-kB and AP-1. (Yoshida et al)

Participants
Input
Output
Participates
as an event of
Inferred From
Interaction of MEKK1 with TRAF6 (Mus musculus)
Orthologous Events
MEKK1 binds TRAF6 (Gallus gallus)
Authored
Garapati, P V  (2010-08-02)
Reviewed
Akira, S  (2010-10-30)
Kawai, T  (2010-10-30)
Created
Garapati, P V  (2010-08-16)
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