Reactome | viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol]

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viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-933473] viral dsRNA:RIG-I/MDA5:TRAF2/TRAF6:IPS-1:RIP-1/FADD:Casp-8/10 prodomain [mitochondrial outer membrane] - Homo sapiens [Complex:R-HSA-936400] dsRNA:DDX58, IFIH1:MAVS:ATG5:ATG12 [mitochondrial outer membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-936378] Inhibition of DDX58/IFIH1 signaling by ATG5:ATG12:MAVS - Homo sapiens [Reaction:R-HSA-937343] NLRC5 interacts with DDX58/IFIH1 - Homo sapiens [Reaction:R-HSA-168909] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS - Homo sapiens
created	[InstanceEdit:918189] Garapati, P V, 2010-08-02
dbId	918192
displayName	viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol]
hasMember	[Complex:R-HSA-913727] viral dsRNA:IFIH1 [cytosol] - Homo sapiens [Complex:R-HSA-918190] 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - Homo sapiens
inDisease	false
maxDepth	4
modified	[InstanceEdit:9835589] Matthews, Lisa, 2023-05-17
name	viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP dsRNA:RIG-I/MDA5
relatedSpecies	[Species:5621375] Hepatitis C Virus [Species:5617433] Rotavirus [Species:9013948] Measles virus [Species:9031716] Influenza A virus [Species:9717528] Human respiratory syncytial virus A
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-918192
updateTrackers	[UpdateTracker:9898703] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v64:[updateContainedMemberOrCandidate] [UpdateTracker:9897591] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v62:[updateContainedMemberOrCandidate] [UpdateTracker:9905426] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v85:[updateContainedMemberOrCandidate] [UpdateTracker:9876935] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v44:[updateContainedMemberOrCandidate] [UpdateTracker:9902282] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v77:[updateContainedMemberOrCandidate] [UpdateTracker:9897172] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v61:[addName, updateContainedMemberOrCandidate] [UpdateTracker:9892625] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v54:[updateContainedMemberOrCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9898703] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v64:[updateContainedMemberOrCandidate] [UpdateTracker:9897591] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v62:[updateContainedMemberOrCandidate] [UpdateTracker:9905426] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v85:[updateContainedMemberOrCandidate] [UpdateTracker:9876935] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v44:[updateContainedMemberOrCandidate] [UpdateTracker:9902282] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v77:[updateContainedMemberOrCandidate] [UpdateTracker:9897172] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v61:[addName, updateContainedMemberOrCandidate] [UpdateTracker:9892625] Update Tracker - [DefinedSet:918192] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP [cytosol] - v54:[updateContainedMemberOrCandidate]
(hasComponent)	[Complex:R-HSA-933473] viral dsRNA:RIG-I/MDA5:TRAF2/TRAF6:IPS-1:RIP-1/FADD:Casp-8/10 prodomain [mitochondrial outer membrane] [Complex:R-HSA-936400] dsRNA:DDX58, IFIH1:MAVS:ATG5:ATG12 [mitochondrial outer membrane] [Complex:R-HSA-983461] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP:K48polyUb-MAVS [mitochondrial outer membrane] [Complex:R-HSA-933467] dsRNA:DDX58/dsRNA:IFIH1:MAVS:TRAF2/TRAF6 [mitochondrial outer membrane] [Complex:R-HSA-918201] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS [mitochondrial outer membrane] [Complex:R-HSA-937325] viral dsRNA:IFIH1, 2xviral dsRNA:2xK63polyUb-DDX58:2xRNF135,TRIM25:2xATP:NLRC5 [cytosol]
(input)	[Reaction:R-HSA-936378] Inhibition of DDX58/IFIH1 signaling by ATG5:ATG12:MAVS [Reaction:R-HSA-937343] NLRC5 interacts with DDX58/IFIH1 [Reaction:R-HSA-168909] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS

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