Reactome | Tn antigens [Golgi lumen]

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Tn antigens [Golgi lumen] Show undefined attributes

compartment	[Compartment:17963] Golgi lumen
consumedByEvent	[FailedReaction:R-HSA-6785524] Defective C1GALT1C1 does not bind C1GALT1 - Homo sapiens [BlackBoxEvent:R-HSA-914006] Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein - Homo sapiens [BlackBoxEvent:R-HSA-914005] Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein - Homo sapiens [Reaction:R-HSA-914010] B3GNT6 transfers GlcNAc to Tn antigen - Homo sapiens [BlackBoxEvent:R-HSA-914017] Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein - Homo sapiens [BlackBoxEvent:R-HSA-914008] Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein - Homo sapiens [Reaction:R-HSA-977071] ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens - Homo sapiens [Reaction:R-HSA-1964505] C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) - Homo sapiens
created	[InstanceEdit:913626] Jassal, B, 2010-07-19
dbId	913659
displayName	Tn antigens [Golgi lumen]
hasMember	[EntityWithAccessionedSequence:R-HSA-913642] GalNAc-MUC1(24-1255) [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-913710] GalNAc-MUC12 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463442] GalNAc-MUC13 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463441] GalNAc-MUC15 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463446] GalNAc-MUC16 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463438] GalNAc-MUC17 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463448] GalNAc-MUC19(?-6254) [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463437] GalNAc-MUC2 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463443] GalNAc-MUC20 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463439] GalNAc-MUC21 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463444] GalNAc-MUC3A [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463447] GalNAc-MUC3B(?-901) [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463433] GalNAc-MUC4(29-4687) [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463440] GalNAc-MUC5AC [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463435] GalNAc-MUC5B(26-5703) [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463436] GalNAc-MUC6(23-2439) [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-1463434] GalNAc-MUC7 [Golgi lumen] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-913643] GalNAc-MUCL1 [Golgi lumen] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-913659] Tn antigens [Golgi lumen] - Mus musculus [DefinedSet:R-RNO-913659] Tn antigens [Golgi lumen] - Rattus norvegicus [DefinedSet:R-CFA-913659] Tn antigens [Golgi lumen] - Canis familiaris [DefinedSet:R-BTA-913659] Tn antigens [Golgi lumen] - Bos taurus [DefinedSet:R-SSC-913659] Tn antigens [Golgi lumen] - Sus scrofa [DefinedSet:R-DRE-913659] Tn antigens [Golgi lumen] - Danio rerio [DefinedSet:R-XTR-913659] Tn antigens [Golgi lumen] - Xenopus tropicalis [DefinedSet:R-GGA-913659] Tn antigens [Golgi lumen] - Gallus gallus [DefinedSet:R-DME-913659] Tn antigens [Golgi lumen] - Drosophila melanogaster [DefinedSet:R-CEL-913659] Tn antigens [Golgi lumen] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-1463448] GalNAc-MUC19(?-6254) [Golgi lumen] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-PFA-1463448] GalNAc-MUC19(?-6254) [Golgi lumen] - Plasmodium falciparum
maxDepth	2
modified	[InstanceEdit:1463449] Wu, G, 2011-07-28
name	Tn antigens N-acetyl-D-galactosaminyl-mucins
producedByEvent	[Reaction:R-HSA-913675] GALNTs transfer GalNAc to Mucins to form Tn antigens - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-913659

Referrals

(input)

[FailedReaction:R-HSA-6785524] Defective C1GALT1C1 does not bind C1GALT1
[BlackBoxEvent:R-HSA-914006] Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein
[BlackBoxEvent:R-HSA-914005] Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein
[Reaction:R-HSA-914010] B3GNT6 transfers GlcNAc to Tn antigen
[BlackBoxEvent:R-HSA-914017] Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein
[BlackBoxEvent:R-HSA-914008] Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein
[Reaction:R-HSA-977071] ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens
[Reaction:R-HSA-1964505] C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)

(output)

[Reaction:R-HSA-913675] GALNTs transfer GalNAc to Mucins to form Tn antigens

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