Reactome | Tn antigens [Golgi lumen]

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Tn antigens [Golgi lumen] Show undefined attributes

compartment	[Compartment:17963] Golgi lumen
consumedByEvent	[BlackBoxEvent:R-BTA-914006] Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein - Bos taurus [BlackBoxEvent:R-BTA-914005] Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein - Bos taurus [Reaction:R-BTA-914010] B3GNT6 transfers GlcNAc to Tn antigen - Bos taurus [BlackBoxEvent:R-BTA-914017] Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein - Bos taurus [BlackBoxEvent:R-BTA-914008] Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein - Bos taurus [Reaction:R-BTA-977071] ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens - Bos taurus [Reaction:R-BTA-1964505] C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10369612
displayName	Tn antigens [Golgi lumen]
hasMember	[EntityWithAccessionedSequence:R-BTA-913642] MUC1 [Golgi lumen] - Bos taurus [EntityWithAccessionedSequence:R-BTA-1463441] MUC15 [Golgi lumen] - Bos taurus [EntityWithAccessionedSequence:R-BTA-1463446] GalNAc-MUC16 [Golgi lumen] - Bos taurus [EntityWithAccessionedSequence:R-BTA-1463443] MUC20 [Golgi lumen] - Bos taurus [EntityWithAccessionedSequence:R-BTA-1463433] GalNAc-MUC4(29-4687) [Golgi lumen] - Bos taurus [EntityWithAccessionedSequence:R-BTA-1463440] GalNAc-MUC5AC [Golgi lumen] - Bos taurus [EntityWithAccessionedSequence:R-BTA-1463435] MUC5B [Golgi lumen] - Bos taurus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-913659] Tn antigens [Golgi lumen] - Homo sapiens
maxDepth	2
name	Tn antigens N-acetyl-D-galactosaminyl-mucins
producedByEvent	[Reaction:R-BTA-913675] GALNTs transfer GalNAc to Mucins to form Tn antigens - Bos taurus
schemaClass	DefinedSet
species	[Species:48898] Bos taurus
stId	R-BTA-913659

Referrals

(input)	[BlackBoxEvent:R-BTA-914006] Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein [BlackBoxEvent:R-BTA-914005] Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein [Reaction:R-BTA-914010] B3GNT6 transfers GlcNAc to Tn antigen [BlackBoxEvent:R-BTA-914017] Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein [BlackBoxEvent:R-BTA-914008] Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein [Reaction:R-BTA-977071] ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens [Reaction:R-BTA-1964505] C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens)
(output)	[Reaction:R-BTA-913675] GALNTs transfer GalNAc to Mucins to form Tn antigens
(inferredTo)	[DefinedSet:R-HSA-913659] Tn antigens [Golgi lumen]

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