Reactome | Calnexin/calreticulin cycle

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Calnexin/calreticulin cycle Show undefined attributes

authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
created	[InstanceEdit:901079] Jassal, B, 2010-07-02
dbId	901042
displayName	Calnexin/calreticulin cycle
edited	[InstanceEdit:901079] Jassal, B, 2010-07-02
eventOf	[Pathway:R-HSA-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-535717] Binding of calnexin/calreticulin to the unfolded protein - Homo sapiens [Reaction:R-HSA-901047] Binding of ERp57 - Homo sapiens [Reaction:R-HSA-548890] Removal of the third glucose by glucosidase II and release from the chaperone - Homo sapiens [Reaction:R-HSA-912291] Incorrectly folded glycoproteins translocate to the ERQC - Homo sapiens [Pathway:R-HSA-901032] ER Quality Control Compartment (ERQC) - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2019-06-12
literatureReference	[LiteratureReference:901083] Getting in and out from calnexin/calreticulin cycles [LiteratureReference:9861532] Contributions of the Lectin and Polypeptide Binding Sites of Calreticulin to Its Chaperone Functions in Vitro and in Cells
maxDepth	3
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Calnexin/calreticulin cycle
orthologousEvent	[Pathway:R-PFA-901042] Calnexin/calreticulin cycle - Plasmodium falciparum [Pathway:R-SCE-901042] Calnexin/calreticulin cycle - Saccharomyces cerevisiae [Pathway:R-SPO-901042] Calnexin/calreticulin cycle - Schizosaccharomyces pombe [Pathway:R-DDI-901042] Calnexin/calreticulin cycle - Dictyostelium discoideum [Pathway:R-CEL-901042] Calnexin/calreticulin cycle - Caenorhabditis elegans [Pathway:R-DME-901042] Calnexin/calreticulin cycle - Drosophila melanogaster [Pathway:R-GGA-901042] Calnexin/calreticulin cycle - Gallus gallus [Pathway:R-XTR-901042] Calnexin/calreticulin cycle - Xenopus tropicalis [Pathway:R-DRE-901042] Calnexin/calreticulin cycle - Danio rerio [Pathway:R-SSC-901042] Calnexin/calreticulin cycle - Sus scrofa [Pathway:R-BTA-901042] Calnexin/calreticulin cycle - Bos taurus [Pathway:R-CFA-901042] Calnexin/calreticulin cycle - Canis familiaris [Pathway:R-RNO-901042] Calnexin/calreticulin cycle - Rattus norvegicus [Pathway:R-MMU-901042] Calnexin/calreticulin cycle - Mus musculus
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:933773] Gagneux, P, 2010-08-17
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-901042
summation	[Summation:901065] The unfolded protein is recognized by a chaperon protein (ca...
updateTrackers	[UpdateTracker:9777763] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v69:[updateIndirectRLE] [UpdateTracker:9790043] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v35:[add_removeHasEvent, updateContainedRLE] [UpdateTracker:9789768] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v37:[updateContainedPathway] [UpdateTracker:9784296] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v54:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9783100] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v57:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9782605] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v59:[add_removeLiteratureReference, updateIndirectRLE] [UpdateTracker:9786873] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v47:[updateContainedPathway] [UpdateTracker:9864177] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v88:[add_removeLiteratureReference, modifyText] [UpdateTracker:9783362] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v56:[updateIndirectRLE]

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle

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