Reactome | Incorrectly folded glycoproteins translocate to the ERQC

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Incorrectly folded glycoproteins translocate to the ERQC Show undefined attributes

authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:927893] endoplasmic reticulum quality control compartment
created	[InstanceEdit:912293] Jassal, B, 2010-07-08
dbId	912291
displayName	Incorrectly folded glycoproteins translocate to the ERQC
edited	[InstanceEdit:912293] Jassal, B, 2010-07-08
eventOf	[Pathway:R-HSA-901042] Calnexin/calreticulin cycle - Homo sapiens
followingEvent	[Reaction:R-HSA-901074] MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) - Homo sapiens
input	[Complex:R-HSA-909547] (un)folded protein:(GlcNAc)2 (Man)9 [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:941858] N-glycan structure dictates extension of protein folding or onset of disposal
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Incorrectly folded glycoproteins translocate to the ERQC
output	[Complex:R-HSA-912283] (un)folded protein:(GlcNAc)2 (Man)9 [endoplasmic reticulum quality control compartment]
precedingEvent	[Reaction:R-HSA-548890] Removal of the third glucose by glucosidase II and release from the chaperone - Homo sapiens
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:933773] Gagneux, P, 2010-08-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-912291
summation	[Summation:912282] Proteins with folding defects get transported to the Endopla...
updateTrackers	[UpdateTracker:9790116] Update Tracker - [Reaction:912291] Incorrectly folded glycoproteins translocate to the ERQC - v35:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9790116] Update Tracker - [Reaction:912291] Incorrectly folded glycoproteins translocate to the ERQC - v35:[modifyText]
(hasEvent)	[Pathway:R-HSA-901042] Calnexin/calreticulin cycle
(precedingEvent)	[Reaction:R-HSA-901074] MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch)

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