Reactome | N-glycan trimming in the ER and Calnexin/Calreticulin cycle

Schema > Pathway > Entries

N-glycan trimming in the ER and Calnexin/Calreticulin cycle Show undefined attributes

authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
created	[InstanceEdit:532665] Jassal, B, 2010-03-02
dbId	532668
displayName	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
edited	[InstanceEdit:532665] Jassal, B, 2010-03-02
eventOf	[Pathway:R-HSA-446203] Asparagine N-linked glycosylation - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:7977] protein folding
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-532678] Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase - Homo sapiens [Reaction:R-HSA-901006] Binding of Malectin - Homo sapiens [Reaction:R-HSA-532667] Removal of the second glucose by glucosidase II - Homo sapiens [Pathway:R-HSA-901042] Calnexin/calreticulin cycle - Homo sapiens [Reaction:R-HSA-8850594] Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins - Homo sapiens [Reaction:R-HSA-8853379] ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2016-12-21
literatureReference	[LiteratureReference:901083] Getting in and out from calnexin/calreticulin cycles
maxDepth	4
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
orthologousEvent	[Pathway:R-PFA-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Plasmodium falciparum [Pathway:R-SCE-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Saccharomyces cerevisiae [Pathway:R-SPO-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Schizosaccharomyces pombe [Pathway:R-DDI-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Dictyostelium discoideum [Pathway:R-CEL-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Caenorhabditis elegans [Pathway:R-DME-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Drosophila melanogaster [Pathway:R-GGA-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Gallus gallus [Pathway:R-XTR-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Xenopus tropicalis [Pathway:R-DRE-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Danio rerio [Pathway:R-SSC-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Sus scrofa [Pathway:R-BTA-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Bos taurus [Pathway:R-CFA-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Canis familiaris [Pathway:R-RNO-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Rattus norvegicus [Pathway:R-MMU-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Mus musculus
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:933773] Gagneux, P, 2010-08-17
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-532668
summation	[Summation:901038] After being synthesized in the ER membrane the 14-sugars lip...
updateTrackers	[UpdateTracker:9785733] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v51:[updateContainedRLE] [UpdateTracker:9784063] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v54:[updateContainedPathway] [UpdateTracker:9786843] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v47:[updateContainedPathway, updateContainedRLE] [UpdateTracker:9864231] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v88:[updateContainedPathway] [UpdateTracker:9790171] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v35:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9783182] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v57:[addHasEvent, updateContainedPathway] [UpdateTracker:9782635] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v59:[updateContainedPathway, updateContainedRLE] [UpdateTracker:9789584] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v37:[updateContainedPathway, updateContainedRLE]

Referrals

(updatedInstance)

[UpdateTracker:9785733] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v51:[updateContainedRLE]
[UpdateTracker:9784063] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v54:[updateContainedPathway]
[UpdateTracker:9786843] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v47:[updateContainedPathway, updateContainedRLE]
[UpdateTracker:9864231] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v88:[updateContainedPathway]
[UpdateTracker:9790171] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9783182] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v57:[addHasEvent, updateContainedPathway]
[UpdateTracker:9782635] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v59:[updateContainedPathway, updateContainedRLE]
[UpdateTracker:9789584] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v37:[updateContainedPathway, updateContainedRLE]

(hasEvent)

[Pathway:R-HSA-446203] Asparagine N-linked glycosylation

Cite Us!