Reactome | Removal of the third glucose by glucosidase II and release from the chaperone

Schema > Reaction > Entries

Removal of the third glucose by glucosidase II and release from the chaperone Show undefined attributes

authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:532675] glucan 1,3-alpha-glucosidase activity of glucosidase II [endoplasmic reticulum lumen]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:548900] Jassal, B, 2010-03-15
dbId	548890
displayName	Removal of the third glucose by glucosidase II and release from the chaperone
edited	[InstanceEdit:548900] Jassal, B, 2010-03-15
eventOf	[Pathway:R-HSA-901042] Calnexin/calreticulin cycle - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-915148] Correctly folded glycoproteins translocate to the Golgi - Homo sapiens [Reaction:R-HSA-912291] Incorrectly folded glycoproteins translocate to the ERQC - Homo sapiens
input	[Complex:R-HSA-901040] unfolded protein:glycan:chaperone:ERp57 [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:532700] The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Removal of the third glucose by glucosidase II and release from the chaperone
output	[Complex:R-HSA-548862] CALR:CANX [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113780] Glc [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:R-HSA-901028] PDIA3 [endoplasmic reticulum lumen] [Complex:R-HSA-901021] unfolded protein:glycan (no glucose) [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-HSA-901047] Binding of ERp57 - Homo sapiens
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:933773] Gagneux, P, 2010-08-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-548890
summation	[Summation:548857] While the protein is bound to the chaperone complex, the gly...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-915148] Correctly folded glycoproteins translocate to the Golgi [Reaction:R-HSA-912291] Incorrectly folded glycoproteins translocate to the ERQC
(hasEvent)	[Pathway:R-HSA-901042] Calnexin/calreticulin cycle

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