Reactome | Calnexin/calreticulin cycle

Schema > Pathway > Entries

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10912178
displayName	Calnexin/calreticulin cycle
eventOf	[Pathway:R-DME-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DME-901047] Binding of ERp57 - Drosophila melanogaster [Pathway:R-DME-901032] ER Quality Control Compartment (ERQC) - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-901042] Calnexin/calreticulin cycle - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Calnexin/calreticulin cycle
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-901042
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DME-532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle
(inferredTo)	[Pathway:R-HSA-901042] Calnexin/calreticulin cycle

Cite Us!