Reactome | IL12RB1 binds TYK2

Schema > Reaction > Entries

authored	[InstanceEdit:8950030] Duenas, Corina, 2016-12-02
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:8950071] Duenas, Corina, 2016-12-02
dbId	8950057
displayName	IL12RB1 binds TYK2
edited	[InstanceEdit:9005965] Duenas, Corina, 2017-05-11
eventOf	[Pathway:R-HSA-9020591] Interleukin-12 signaling - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-447130] Interleukin-23 binds interleukin-23 receptor - Homo sapiens
inferredFrom	[Reaction:R-MMU-8950034] Il12rb1 binds Tyk2 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-447227] IL12RB1 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-877348] TYK2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IL12RB1 binds TYK2 Interleukin-12 receptor subunit beta 1 binds Non-receptor tyrosine-protein kinase TYK2
output	[Complex:R-HSA-8950046] IL12RB1:TYK2 [plasma membrane]
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9006071] van de Vosse, Esther, 2017-05-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8950057
summation	[Summation:8950038] The intracellular domain of human Interleukin-12 receptor su...

(precedingEvent)	[BlackBoxEvent:R-HSA-447130] Interleukin-23 binds interleukin-23 receptor
(hasEvent)	[Pathway:R-HSA-9020591] Interleukin-12 signaling
(inferredTo)	[Reaction:R-MMU-8950034] Il12rb1 binds Tyk2

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