SCF(SKP2) polyubiquitinates RUNX2

authored
catalystActivity
catalystActivityReference [CatalystActivityReference:9643203] ubiquitin protein ligase activity of RUNX2:SCF(SKP2) [nucleoplasm] Skp2 inhibits osteogenesis by promoting ubiquitin-proteasome degradation of Runx2
category transition
compartment
created [InstanceEdit:8939709] Orlic-Milacic, Marija, 2016-09-21
dbId 8939706
displayName SCF(SKP2) polyubiquitinates RUNX2
edited
eventOf
followingEvent
input
isChimeric false
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name
  • SCF(SKP2) polyubiquitinates RUNX2
orthologousEvent
output
precedingEvent
releaseDate 2017-09-12
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass Reaction
species
stId R-HSA-8939706
summation
updateTrackers
Cite Us!