Reactome | SCF (SKP2) complex [nucleoplasm]

Schema > Complex > Entries

SCF (SKP2) complex [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:9032188] ubiquitin protein ligase activity of SCF (SKP2) complex [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-8939702] RUNX2:SCF(SKP2) [nucleoplasm] - Homo sapiens [Complex:R-HSA-9708443] BACH1:FBXL17:SCF (SKP2) [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8939688] SCF(SKP2) complex binds RUNX2 - Homo sapiens [Reaction:R-HSA-9708525] BACH1:FBXL17 binds SCF(SKP2) complex - Homo sapiens
created	[InstanceEdit:8939694] Orlic-Milacic, Marija, 2016-09-21
dbId	8939693
displayName	SCF (SKP2) complex [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-187551] CUL1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1234142] RBX1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-187538] SKP1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-975554] SKP2 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-8939693] SCF (SKP2) complex [nucleoplasm] - Mus musculus [Complex:R-RNO-8939693] SCF (SKP2) complex [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-8939693] SCF (SKP2) complex [nucleoplasm] - Canis familiaris [Complex:R-BTA-8939693] SCF (SKP2) complex [nucleoplasm] - Bos taurus [Complex:R-SSC-8939693] SCF (SKP2) complex [nucleoplasm] - Sus scrofa [Complex:R-DRE-8939693] SCF (SKP2) complex [nucleoplasm] - Danio rerio [Complex:R-GGA-8939693] SCF (SKP2) complex [nucleoplasm] - Gallus gallus [Complex:R-DME-8939693] SCF (SKP2) complex [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-8939693] SCF (SKP2) complex [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-8939693] SCF (SKP2) complex [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-8939693] SCF (SKP2) complex [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-8939693] SCF (SKP2) complex [nucleoplasm] - Saccharomyces cerevisiae [Complex:R-PFA-8939693] SCF (SKP2) complex [nucleoplasm] - Plasmodium falciparum
literatureReference	[LiteratureReference:208138] Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
maxDepth	2
modified	[InstanceEdit:9709453] Stephan, Ralf, 2020-12-14
name	SCF (SKP2) complex CUL1:SKP1:SKP2:RBX1
producedByEvent	[Reaction:R-HSA-8939706] SCF(SKP2) polyubiquitinates RUNX2 - Homo sapiens [Reaction:R-HSA-9708517] FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8939693
updateTrackers	[UpdateTracker:9902020] Update Tracker - [Complex:8939693] SCF (SKP2) complex [nucleoplasm] - v76:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9902020] Update Tracker - [Complex:8939693] SCF (SKP2) complex [nucleoplasm] - v76:[modifyName]
(input)	[Reaction:R-HSA-9708525] BACH1:FBXL17 binds SCF(SKP2) complex [Reaction:R-HSA-8939688] SCF(SKP2) complex binds RUNX2
(output)	[Reaction:R-HSA-9708517] FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) [Reaction:R-HSA-8939706] SCF(SKP2) polyubiquitinates RUNX2
(hasComponent)	[Complex:R-HSA-9708443] BACH1:FBXL17:SCF (SKP2) [nucleoplasm] [Complex:R-HSA-8939702] RUNX2:SCF(SKP2) [nucleoplasm]
(activeUnit)	[CatalystActivity:8939717] ubiquitin protein ligase activity of RUNX2:SCF(SKP2) [nucleoplasm]
(physicalEntity)	[CatalystActivity:9032188] ubiquitin protein ligase activity of SCF (SKP2) complex [nucleoplasm]

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