Reactome | 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane]

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2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8854776] 2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] - Homo sapiens [Complex:R-HSA-8854768] 2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8853753] 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 - Homo sapiens [Reaction:R-HSA-8853755] 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 - Homo sapiens [Reaction:R-HSA-8855915] 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors - Homo sapiens [Reaction:R-HSA-8855564] 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 - Homo sapiens [Reaction:R-HSA-8855747] 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP - Homo sapiens [Reaction:R-HSA-8854899] 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 - Homo sapiens [Reaction:R-HSA-8853737] 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 - Homo sapiens [Reaction:R-HSA-8855617] 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 - Homo sapiens
created	[InstanceEdit:8854161] Jupe, Steve, 2016-01-27
dbId	8854160
displayName	2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane]
hasComponent	2 × [DefinedSet:R-HSA-8855746] p-5Y-RET:GFRA:GDNF complexes [plasma membrane]
inDisease	false
inferredTo	[Complex:R-MMU-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Mus musculus [Complex:R-RNO-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Rattus norvegicus [Complex:R-CFA-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Canis familiaris [Complex:R-BTA-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Bos taurus [Complex:R-SSC-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Sus scrofa [Complex:R-DRE-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Danio rerio [Complex:R-XTR-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Gallus gallus [Complex:R-DME-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Caenorhabditis elegans
isChimeric	false
maxDepth	6
memberOf	[DefinedSet:R-HSA-8854900] p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane] - Homo sapiens
modified	[InstanceEdit:8855737] Jupe, Steve, 2016-02-05
name	2x p-5Y-RET:GDNF:GFRA complexes
producedByEvent	[Reaction:R-HSA-8853792] RET tyrosine phosphorylation - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8854160

Referrals

(hasComponent)	[Complex:R-HSA-8854768] 2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] [Complex:R-HSA-8854776] 2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] [Complex:R-HSA-8855914] 2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane] [Complex:R-HSA-8855579] 2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] [Complex:R-HSA-8854983] 2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] [Complex:R-HSA-8855573] 2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6 [plasma membrane] [Complex:R-HSA-8855748] 2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP [plasma membrane] [Complex:R-HSA-8854400] 2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] [Complex:R-HSA-8854980] 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] [Complex:R-HSA-8854903] 2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane]
(input)	[Reaction:R-HSA-8853753] 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 [Reaction:R-HSA-8853755] 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 [Reaction:R-HSA-8855915] 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors [Reaction:R-HSA-8855564] 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 [Reaction:R-HSA-8855617] 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 [Reaction:R-HSA-8855747] 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP [Reaction:R-HSA-8854899] 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 [Reaction:R-HSA-8853737] 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1
(hasMember)	[DefinedSet:R-HSA-8854900] p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane]
(output)	[Reaction:R-HSA-8853792] RET tyrosine phosphorylation

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