Reactome | 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane]

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2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-8854776] 2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] - Sus scrofa [Complex:R-SSC-8854768] 2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-8853753] 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 - Sus scrofa [Reaction:R-SSC-8853755] 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 - Sus scrofa [Reaction:R-SSC-8855915] 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors - Sus scrofa [Reaction:R-SSC-8855564] 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 - Sus scrofa [Reaction:R-SSC-8855747] 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP - Sus scrofa [Reaction:R-SSC-8854899] 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 - Sus scrofa [Reaction:R-SSC-8853737] 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 - Sus scrofa [Reaction:R-SSC-8855617] 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10518633
displayName	2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane]
hasComponent	2 × [DefinedSet:R-SSC-8855746] p-5Y-RET:GFRA:GDNF complexes [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] - Homo sapiens
maxDepth	6
memberOf	[DefinedSet:R-SSC-8854900] p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane] - Sus scrofa
name	2x p-5Y-RET:GDNF:GFRA complexes
producedByEvent	[Reaction:R-SSC-8853792] RET tyrosine phosphorylation - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-8854160
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-SSC-8853753] 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 [Reaction:R-SSC-8853755] 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 [Reaction:R-SSC-8855915] 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors [Reaction:R-SSC-8855564] 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 [Reaction:R-SSC-8855617] 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 [Reaction:R-SSC-8855747] 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP [Reaction:R-SSC-8854899] 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 [Reaction:R-SSC-8853737] 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1
(hasComponent)	[Complex:R-SSC-8854768] 2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] [Complex:R-SSC-8854776] 2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] [Complex:R-SSC-8855914] 2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane] [Complex:R-SSC-8855579] 2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] [Complex:R-SSC-8854983] 2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] [Complex:R-SSC-8855573] 2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6 [plasma membrane] [Complex:R-SSC-8855748] 2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP [plasma membrane] [Complex:R-SSC-8854400] 2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] [Complex:R-SSC-8854980] 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] [Complex:R-SSC-8854903] 2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane]
(hasMember)	[DefinedSet:R-SSC-8854900] p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane]
(output)	[Reaction:R-SSC-8853792] RET tyrosine phosphorylation
(inferredTo)	[Complex:R-HSA-8854160] 2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane]

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