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Schema
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Pathway
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Entries
Recycling of eIF2:GDP
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compartment
[Compartment:70101] cytosol
dbId
72731
displayName
Recycling of eIF2:GDP
eventOf
[Pathway:R-HSA-72737] Cap-dependent Translation Initiation - Homo sapiens
hasDiagram
false
hasEHLD
false
hasEvent
[Reaction:R-HSA-72670] Formation of eIF2:GDP:eIF2B intermediate - Homo sapiens
[Reaction:R-HSA-72722] eIF2 activation - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2011-09-30
literatureReference
[LiteratureReference:72733] Phosphorylation inhibits guanine nucleotide exchange on eukaryotic initiation factor 2.
maxDepth
2
modified
[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name
Recycling of eIF2:GDP
orthologousEvent
[Pathway:R-RNO-72731] Recycling of eIF2:GDP - Rattus norvegicus
[Pathway:R-PFA-72731] Recycling of eIF2:GDP - Plasmodium falciparum
[Pathway:R-SCE-72731] Recycling of eIF2:GDP - Saccharomyces cerevisiae
[Pathway:R-SPO-72731] Recycling of eIF2:GDP - Schizosaccharomyces pombe
[Pathway:R-DDI-72731] Recycling of eIF2:GDP - Dictyostelium discoideum
[Pathway:R-CEL-72731] Recycling of eIF2:GDP - Caenorhabditis elegans
[Pathway:R-DME-72731] Recycling of eIF2:GDP - Drosophila melanogaster
[Pathway:R-GGA-72731] Recycling of eIF2:GDP - Gallus gallus
[Pathway:R-DRE-72731] Recycling of eIF2:GDP - Danio rerio
[Pathway:R-SSC-72731] Recycling of eIF2:GDP - Sus scrofa
[Pathway:R-BTA-72731] Recycling of eIF2:GDP - Bos taurus
[Pathway:R-CFA-72731] Recycling of eIF2:GDP - Canis familiaris
[Pathway:R-MMU-72731] Recycling of eIF2:GDP - Mus musculus
precedingEvent
[Pathway:R-HSA-72706] GTP hydrolysis and joining of the 60S ribosomal subunit - Homo sapiens
releaseDate
2004-07-06
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-72731
summation
[Summation:72732] The active eIF2:GTP complex may be formed by direct binding ...
updateTrackers
[UpdateTracker:9789516] Update Tracker - [Pathway:72731] Recycling of eIF2:GDP - v38:[addLiteratureReference]
Referrals
(updatedInstance)
[UpdateTracker:9789516] Update Tracker - [Pathway:72731] Recycling of eIF2:GDP - v38:[addLiteratureReference]
(hasEvent)
[Pathway:R-HSA-72737] Cap-dependent Translation Initiation
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