Reactome | Cap-dependent Translation Initiation

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Cap-dependent Translation Initiation Show undefined attributes

created	[InstanceEdit:72607] Merrick, WC, 2002-12-16 00:00:00
dbId	72737
displayName	Cap-dependent Translation Initiation
eventOf	[Pathway:R-HSA-72613] Eukaryotic Translation Initiation - Homo sapiens
figure	[Figure:69876] /figures/translation_fig1.jpg
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-72689] Formation of a pool of free 40S subunits - Homo sapiens [Pathway:R-HSA-72695] Formation of the ternary complex, and subsequently, the 43S complex - Homo sapiens [Pathway:R-HSA-72662] Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S - Homo sapiens [Pathway:R-HSA-72702] Ribosomal scanning and start codon recognition - Homo sapiens [Pathway:R-HSA-72706] GTP hydrolysis and joining of the 60S ribosomal subunit - Homo sapiens [Pathway:R-HSA-72731] Recycling of eIF2:GDP - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2018-09-30
maxDepth	4
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Cap-dependent Translation Initiation
orthologousEvent	[Pathway:R-RNO-72737] Cap-dependent Translation Initiation - Rattus norvegicus [Pathway:R-PFA-72737] Cap-dependent Translation Initiation - Plasmodium falciparum [Pathway:R-SCE-72737] Cap-dependent Translation Initiation - Saccharomyces cerevisiae [Pathway:R-SPO-72737] Cap-dependent Translation Initiation - Schizosaccharomyces pombe [Pathway:R-DDI-72737] Cap-dependent Translation Initiation - Dictyostelium discoideum [Pathway:R-CEL-72737] Cap-dependent Translation Initiation - Caenorhabditis elegans [Pathway:R-DME-72737] Cap-dependent Translation Initiation - Drosophila melanogaster [Pathway:R-GGA-72737] Cap-dependent Translation Initiation - Gallus gallus [Pathway:R-XTR-72737] Cap-dependent Translation Initiation - Xenopus tropicalis [Pathway:R-DRE-72737] Cap-dependent Translation Initiation - Danio rerio [Pathway:R-SSC-72737] Cap-dependent Translation Initiation - Sus scrofa [Pathway:R-BTA-72737] Cap-dependent Translation Initiation - Bos taurus [Pathway:R-CFA-72737] Cap-dependent Translation Initiation - Canis familiaris [Pathway:R-MMU-72737] Cap-dependent Translation Initiation - Mus musculus
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-72737
summation	[Summation:72738] Translation initiation is a complex process in which the Met...
updateTrackers	[UpdateTracker:9779159] Update Tracker - [Pathway:72737] Cap-dependent Translation Initiation - v66:[updateIndirectRLE] [UpdateTracker:9789499] Update Tracker - [Pathway:72737] Cap-dependent Translation Initiation - v38:[updateContainedPathway]

Referrals

(updatedInstance)	[UpdateTracker:9779159] Update Tracker - [Pathway:72737] Cap-dependent Translation Initiation - v66:[updateIndirectRLE] [UpdateTracker:9789499] Update Tracker - [Pathway:72737] Cap-dependent Translation Initiation - v38:[updateContainedPathway]
(hasEvent)	[Pathway:R-HSA-72613] Eukaryotic Translation Initiation

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