Reactome | EIF1AX [cytosol]

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EIF1AX [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-72570] 40S:eIF3:eIF1A [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-72676] eIF3 and eIF1A bind to the 40S subunit - Homo sapiens [Reaction:R-HSA-72673] Release of 40S and 60S subunits from the 80S ribosome - Homo sapiens [Reaction:R-HSA-157849] Formation of translation initiation complexes containing mRNA that does not circularize - Homo sapiens [Reaction:R-HSA-72697] Start codon recognition - Homo sapiens [Reaction:R-HSA-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation - Homo sapiens
dbId	72557
displayName	EIF1AX [cytosol]
endCoordinate	144
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-72557] Eif1ax [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-72557] Eif1a [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-72557] EIF1AX [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-72557] EIF1AX [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-72557] EIF1AX [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-72557] wu:fb26b09 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-72557] eif1ax [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-72557] EIF1AX [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-72557] eIF1A [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-72557] eif-1.a [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-72557] eif1a [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-72557] tif11 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-72557] TIF11 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-72557] EIF1AX [cytosol] - Plasmodium falciparum
literatureReference	[LiteratureReference:72558] Determination of the amino acid sequence of rabbit, human, and wheat germ protein synthesis factor eIF-4C by cloning and chemical sequencing [LiteratureReference:72567] Functional coherence of the human Y chromosome
modified	[InstanceEdit:4084595] Orlic-Milacic, M, 2013-07-29
name	EIF1AX eIF1A eIF-1A eIF-4C eukaryotic translation initiation factor 1A Eukaryotic translation initiation factor 1A, X-chromosomal eIF-1A X isoform
producedByEvent	[Reaction:R-HSA-72673] Release of 40S and 60S subunits from the 80S ribosome - Homo sapiens [Reaction:R-HSA-157849] Formation of translation initiation complexes containing mRNA that does not circularize - Homo sapiens [Reaction:R-HSA-72697] Start codon recognition - Homo sapiens [Reaction:R-HSA-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation - Homo sapiens [Reaction:R-HSA-72619] eIF2:GTP is hydrolyzed, eIFs are released - Homo sapiens
referenceEntity	[ReferenceGeneProduct:72556] UniProt:P47813 EIF1AX
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-72557
startCoordinate	1

Referrals

(input)	[Reaction:R-HSA-72676] eIF3 and eIF1A bind to the 40S subunit [Reaction:R-HSA-72673] Release of 40S and 60S subunits from the 80S ribosome [Reaction:R-HSA-72697] Start codon recognition [Reaction:R-HSA-157849] Formation of translation initiation complexes containing mRNA that does not circularize [Reaction:R-HSA-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation
(output)	[Reaction:R-HSA-72673] Release of 40S and 60S subunits from the 80S ribosome [Reaction:R-HSA-72619] eIF2:GTP is hydrolyzed, eIFs are released [Reaction:R-HSA-72697] Start codon recognition [Reaction:R-HSA-157849] Formation of translation initiation complexes containing mRNA that does not circularize [Reaction:R-HSA-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation
(hasComponent)	[Complex:R-HSA-72570] 40S:eIF3:eIF1A [cytosol] [Complex:R-HSA-72571] 43S complex [cytosol]

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