Reactome | Release of 40S and 60S subunits from the 80S ribosome

Schema > Reaction > Entries

Release of 40S and 60S subunits from the 80S ribosome Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol
dbId	72673
displayName	Release of 40S and 60S subunits from the 80S ribosome
eventOf	[Pathway:R-HSA-72689] Formation of a pool of free 40S subunits - Homo sapiens
followingEvent	[Reaction:R-HSA-72672] The 60S subunit joins the translation initiation complex - Homo sapiens [Reaction:R-HSA-72676] eIF3 and eIF1A bind to the 40S subunit - Homo sapiens
input	[Complex:R-HSA-72500] 80S ribosome [cytosol] [EntityWithAccessionedSequence:R-HSA-72557] EIF1AX [cytosol]
isInDisease	false
isInferred	false
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Release of 40S and 60S subunits from the 80S ribosome
orthologousEvent	[Reaction:R-RNO-72673] Release of 40S and 60S subunits from the 80S ribosome - Rattus norvegicus [Reaction:R-PFA-72673] Release of 40S and 60S subunits from the 80S ribosome - Plasmodium falciparum [Reaction:R-SCE-72673] Release of 40S and 60S subunits from the 80S ribosome - Saccharomyces cerevisiae [Reaction:R-SPO-72673] Release of 40S and 60S subunits from the 80S ribosome - Schizosaccharomyces pombe [Reaction:R-DDI-72673] Release of 40S and 60S subunits from the 80S ribosome - Dictyostelium discoideum [Reaction:R-CEL-72673] Release of 40S and 60S subunits from the 80S ribosome - Caenorhabditis elegans [Reaction:R-DME-72673] Release of 40S and 60S subunits from the 80S ribosome - Drosophila melanogaster [Reaction:R-DRE-72673] Release of 40S and 60S subunits from the 80S ribosome - Danio rerio [Reaction:R-SSC-72673] Release of 40S and 60S subunits from the 80S ribosome - Sus scrofa [Reaction:R-BTA-72673] Release of 40S and 60S subunits from the 80S ribosome - Bos taurus [Reaction:R-CFA-72673] Release of 40S and 60S subunits from the 80S ribosome - Canis familiaris [Reaction:R-MMU-72673] Release of 40S and 60S subunits from the 80S ribosome - Mus musculus
output	[Complex:R-HSA-72392] 40S ribosomal complex [cytosol] [Complex:R-HSA-72499] 60S ribosomal complex [cytosol] [EntityWithAccessionedSequence:R-HSA-72557] EIF1AX [cytosol]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-72673
summation	[Summation:72674] 80S monosomes dissociate into 40S and 60S ribosomal subunits...

Referrals

(precedingEvent)	[Reaction:R-HSA-72672] The 60S subunit joins the translation initiation complex [Reaction:R-HSA-72676] eIF3 and eIF1A bind to the 40S subunit
(hasEvent)	[Pathway:R-HSA-72689] Formation of a pool of free 40S subunits