Reactome | eIF1A [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DME-72570] 40S:eIF3:eIF1A [cytosol] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-72676] eIF3 and eIF1A bind to the 40S subunit - Drosophila melanogaster [Reaction:R-DME-72673] Release of 40S and 60S subunits from the 80S ribosome - Drosophila melanogaster [Reaction:R-DME-157849] Formation of translation initiation complexes containing mRNA that does not circularize - Drosophila melanogaster [Reaction:R-DME-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation - Drosophila melanogaster [Reaction:R-DME-72697] Start codon recognition - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10832485
displayName	eIF1A [cytosol]
endCoordinate	144
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-72557] EIF1AX [cytosol] - Homo sapiens
maxDepth	1
name	eIF1A EIF1AX Q9VEA1
producedByEvent	[Reaction:R-DME-72673] Release of 40S and 60S subunits from the 80S ribosome - Drosophila melanogaster [Reaction:R-DME-157849] Formation of translation initiation complexes containing mRNA that does not circularize - Drosophila melanogaster [Reaction:R-DME-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation - Drosophila melanogaster [Reaction:R-DME-72697] Start codon recognition - Drosophila melanogaster
referenceEntity	[ReferenceGeneProduct:uniprot:Q9VEA1] UniProt:Q9VEA1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:56210] Drosophila melanogaster
stId	R-DME-72557
startCoordinate	1

(output)	[Reaction:R-DME-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation [Reaction:R-DME-72673] Release of 40S and 60S subunits from the 80S ribosome [Reaction:R-DME-72697] Start codon recognition [Reaction:R-DME-157849] Formation of translation initiation complexes containing mRNA that does not circularize
(input)	[Reaction:R-DME-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation [Reaction:R-DME-72676] eIF3 and eIF1A bind to the 40S subunit [Reaction:R-DME-72673] Release of 40S and 60S subunits from the 80S ribosome [Reaction:R-DME-72697] Start codon recognition [Reaction:R-DME-157849] Formation of translation initiation complexes containing mRNA that does not circularize
(hasComponent)	[Complex:R-DME-72570] 40S:eIF3:eIF1A [cytosol] [Complex:R-DME-72571] 43S complex [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-72557] EIF1AX [cytosol]

eIF1A [cytosol] Show undefined attributes

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