Inner coat assembly and cargo binding

Stable Identifier
R-HSA-5694522
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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SAR1:GTP recruits the cytoplasmic SEC23:SEC24 complex. SEC24, and to a lesser extent SEC23, also mediate interaction with COPII cargo, concentrating it into the emerging vesicle. Transmembrane cargo may interact directly with the inner coat proteins, often in an isoform specific manner; alternately, some transmembrane proteins and all soluble cargo interact first with a cargo receptor of the p24, LMAN or ERV families.

Literature References
PubMed ID Title Journal Year
10982397 Dynamics of transitional endoplasmic reticulum sites in vertebrate cells

Hammond, AT, Glick, BS

Mol Biol Cell 2000
10825291 COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites

Stephens, DJ, Lin-Marq, N, Pagano, A, Pepperkok, R, Paccaud, JP

J Cell Sci 2000
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