Reactome | Inner coat assembly and cargo binding

Schema > Reaction > Entries

Inner coat assembly and cargo binding Show undefined attributes

category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10063965
displayName	Inner coat assembly and cargo binding
eventOf	[Pathway:R-MMU-204005] COPII-mediated vesicle transport - Mus musculus [Pathway:R-MMU-5694530] Cargo concentration in the ER - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-5694417] SEC16 complex binds SAR1B:GTP:SEC23:SEC24 - Mus musculus [Reaction:R-MMU-5694527] Loss of SAR1B GTPase - Mus musculus
inferredFrom	[Reaction:R-HSA-5694522] Inner coat assembly and cargo binding - Homo sapiens
input	[DefinedSet:R-MMU-5694244] COPII cargo:receptors [endoplasmic reticulum membrane] [Complex:R-MMU-204003] SAR1B:GTP [endoplasmic reticulum membrane] [Complex:R-MMU-203975] SEC23:SEC24 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Inner coat assembly and cargo binding
output	[Complex:R-MMU-5694523] COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-MMU-203977] SAR1 Activation And Membrane Binding - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5694522
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-204005] COPII-mediated vesicle transport [Pathway:R-MMU-5694530] Cargo concentration in the ER
(precedingEvent)	[Reaction:R-MMU-5694417] SEC16 complex binds SAR1B:GTP:SEC23:SEC24 [Reaction:R-MMU-5694527] Loss of SAR1B GTPase
(inferredTo)	[Reaction:R-HSA-5694522] Inner coat assembly and cargo binding