Reactome | SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]

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SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] Show undefined attributes

compartment	[Compartment:12045] endoplasmic reticulum membrane
componentOf	[Complex:R-HSA-5362408] ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Homo sapiens [Complex:R-HSA-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5387386] Hh processing variants are recruited to SEL1:SYVN at the ER membrane - Homo sapiens [Reaction:R-HSA-5362441] C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane - Homo sapiens
created	[InstanceEdit:5362379] Rothfels, Karen, 2014-04-15
dbId	5362378
displayName	SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-5362350] DERL2 [endoplasmic reticulum membrane] [EntityWithAccessionedSequence:R-HSA-1911545] SEL1L [endoplasmic reticulum membrane] [Complex:R-HSA-5362361] SYVN1 dimer [endoplasmic reticulum membrane] [Complex:R-HSA-5362364] VCP hexamer [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Mus musculus [Complex:R-RNO-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Rattus norvegicus [Complex:R-CFA-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Canis familiaris [Complex:R-BTA-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Bos taurus [Complex:R-SSC-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Sus scrofa [Complex:R-DRE-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Danio rerio [Complex:R-XTR-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Xenopus tropicalis [Complex:R-GGA-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Gallus gallus [Complex:R-DME-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Drosophila melanogaster [Complex:R-CEL-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Caenorhabditis elegans [Complex:R-DDI-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Dictyostelium discoideum [Complex:R-SPO-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Schizosaccharomyces pombe
isChimeric	false
maxDepth	3
name	SEL1:SYVN1 dimer:DERL2:VCP hexamer
producedByEvent	[Reaction:R-HSA-5362459] VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol - Homo sapiens [Reaction:R-HSA-5387389] Hh processing variants are translocated to the cytosol in a VCP-dependent manner - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5362378

Referrals

(input)	[Reaction:R-HSA-5362441] C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane [Reaction:R-HSA-5387386] Hh processing variants are recruited to SEL1:SYVN at the ER membrane
(hasComponent)	[Complex:R-HSA-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] [Complex:R-HSA-5362408] ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] [Complex:R-HSA-5387378] SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] [Complex:R-HSA-5483239] ub-SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
(output)	[Reaction:R-HSA-5362459] VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol [Reaction:R-HSA-5387389] Hh processing variants are translocated to the cytosol in a VCP-dependent manner

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