Reactome | SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:5483235] ubiquitin-protein transferase activity of SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane
consumedByEvent	[Reaction:R-HSA-5483238] Hh processing variants are ubiquitinated - Homo sapiens
created	[InstanceEdit:5387379] Rothfels, Karen, 2014-04-29
dbId	5387378
displayName	SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
hasComponent	[Complex:R-HSA-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] [Complex:R-HSA-5362380] SHH processing variants:OS9/ERLEC1 [endoplasmic reticulum lumen]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:17957] endoplasmic reticulum lumen [Compartment:927893] endoplasmic reticulum quality control compartment
isChimeric	false
name	SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer
producedByEvent	[Reaction:R-HSA-5387386] Hh processing variants are recruited to SEL1:SYVN at the ER membrane - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5387378

(output)	[Reaction:R-HSA-5387386] Hh processing variants are recruited to SEL1:SYVN at the ER membrane
(input)	[Reaction:R-HSA-5483238] Hh processing variants are ubiquitinated
(diseaseEntity)	[EntityFunctionalStatus:9630074] gain_of_function of SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
(physicalEntity)	[CatalystActivity:5483235] ubiquitin-protein transferase activity of SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]

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