Reactome | C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]

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C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] Show undefined attributes

catalystActivities	[CatalystActivity:5362410] ubiquitin-protein transferase activity of C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane
consumedByEvent	[Reaction:R-HSA-5362412] SYVN1 ubiquitinates Hh C-terminal fragments - Homo sapiens
created	[InstanceEdit:5362415] Rothfels, Karen, 2014-04-15
dbId	5362413
displayName	C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
hasComponent	[Complex:R-HSA-5362409] C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] [Complex:R-HSA-5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:17957] endoplasmic reticulum lumen [Compartment:927893] endoplasmic reticulum quality control compartment
inferredTo	[Complex:R-MMU-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Mus musculus [Complex:R-RNO-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Rattus norvegicus [Complex:R-CFA-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Canis familiaris [Complex:R-BTA-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Bos taurus [Complex:R-SSC-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Sus scrofa [Complex:R-DRE-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Danio rerio [Complex:R-XTR-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Xenopus tropicalis [Complex:R-GGA-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Gallus gallus [Complex:R-DME-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Drosophila melanogaster [Complex:R-CEL-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Caenorhabditis elegans [Complex:R-DDI-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Dictyostelium discoideum [Complex:R-SPO-5362413] C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - Schizosaccharomyces pombe
isChimeric	false
literatureReference	[LiteratureReference:5359146] Derlin2 protein facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum
name	C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer
producedByEvent	[Reaction:R-HSA-5362441] C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5362413

Referrals

(output)	[Reaction:R-HSA-5362441] C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane
(input)	[Reaction:R-HSA-5362412] SYVN1 ubiquitinates Hh C-terminal fragments
(physicalEntity)	[CatalystActivity:5362410] ubiquitin-protein transferase activity of C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]

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