Reactome | BCL2 [mitochondrial outer membrane]

Schema > EntityWithAccessionedSequence > Entries

BCL2 [mitochondrial outer membrane] Show undefined attributes

compartment	[Compartment:17906] mitochondrial outer membrane
componentOf	[Complex:R-HSA-9692353] BCL2:BCL2 antagonists [mitochondrial outer membrane] - Homo sapiens [Complex:R-HSA-114268] BAD:BCL-2 [mitochondrial outer membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9692376] BCL2 binds BCL2 antagonists - Homo sapiens [Reaction:R-HSA-508163] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 - Homo sapiens [Reaction:R-HSA-114352] Sequestration of tBID by BCL-2 - Homo sapiens
dbId	50757
displayName	BCL2 [mitochondrial outer membrane]
endCoordinate	239
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-50757] Bcl2 [mitochondrial outer membrane] - Mus musculus [EntityWithAccessionedSequence:R-CFA-50757] BCL2 [mitochondrial outer membrane] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-50757] BCL2 [mitochondrial outer membrane] - Bos taurus [EntityWithAccessionedSequence:R-SSC-50757] KDSR [mitochondrial outer membrane] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-50757] bcl2b [mitochondrial outer membrane] - Danio rerio [EntityWithAccessionedSequence:R-XTR-50757] bcl2 [mitochondrial outer membrane] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-50757] BCL2 [mitochondrial outer membrane] - Gallus gallus [EntityWithAccessionedSequence:R-CEL-50757] ced-9 [mitochondrial outer membrane] - Caenorhabditis elegans
maxDepth	1
memberOf	[DefinedSet:R-HSA-879209] Bcl-2/Bcl-X(L) [mitochondrial outer membrane] - Homo sapiens
modified	[InstanceEdit:3132750] Wu, G, 2013-02-13
name	BCL2 Bcl-2 protein
producedByEvent	[BlackBoxEvent:R-HSA-9011941] Estrogen-responsive BCL2 gene expression - Homo sapiens [BlackBoxEvent:R-HSA-9824587] MITF-M-dependent BCL2 expression - Homo sapiens [BlackBoxEvent:R-HSA-9796055] NFE2L2 dependent BCL2 expression - Homo sapiens [BlackBoxEvent:R-HSA-9623999] BCL gene expression downstream of ESR1 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P10415] UniProt:P10415 BCL2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-50757
startCoordinate	1
updateTrackers	[UpdateTracker:9877742] Update Tracker - [EntityWithAccessionedSequence:50757] BCL2 [mitochondrial outer membrane] - v44:[modifyEndCoordinate] [UpdateTracker:9871330] Update Tracker - [EntityWithAccessionedSequence:50757] BCL2 [mitochondrial outer membrane] - v39:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9877742] Update Tracker - [EntityWithAccessionedSequence:50757] BCL2 [mitochondrial outer membrane] - v44:[modifyEndCoordinate] [UpdateTracker:9871330] Update Tracker - [EntityWithAccessionedSequence:50757] BCL2 [mitochondrial outer membrane] - v39:[addName]
(output)	[BlackBoxEvent:R-HSA-9011941] Estrogen-responsive BCL2 gene expression [BlackBoxEvent:R-HSA-9824587] MITF-M-dependent BCL2 expression [BlackBoxEvent:R-HSA-9796055] NFE2L2 dependent BCL2 expression [BlackBoxEvent:R-HSA-9623999] BCL gene expression downstream of ESR1
(hasComponent)	[Complex:R-HSA-9692353] BCL2:BCL2 antagonists [mitochondrial outer membrane] [Complex:R-HSA-508158] Bcl2:BH3-only protein complex [mitochondrial outer membrane] [Complex:R-HSA-114268] BAD:BCL-2 [mitochondrial outer membrane] [Complex:R-HSA-114339] tBID:BCL-2 [mitochondrial outer membrane]
(input)	[Reaction:R-HSA-9692376] BCL2 binds BCL2 antagonists [Reaction:R-HSA-508163] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 [Reaction:R-HSA-114352] Sequestration of tBID by BCL-2
(hasMember)	[DefinedSet:R-HSA-879209] Bcl-2/Bcl-X(L) [mitochondrial outer membrane]

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