Reactome | BCL2 [mitochondrial outer membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:17906] mitochondrial outer membrane
componentOf	[Complex:R-BTA-9692353] BCL2:BCL2 antagonists [mitochondrial outer membrane] - Bos taurus [Complex:R-BTA-114268] BAD:BCL-2 [mitochondrial outer membrane] - Bos taurus
consumedByEvent	[Reaction:R-BTA-9692376] BCL2 binds BCL2 antagonists - Bos taurus [Reaction:R-BTA-508163] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 - Bos taurus [Reaction:R-BTA-114352] Sequestration of tBID by BCL-2 - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10341382
displayName	BCL2 [mitochondrial outer membrane]
endCoordinate	239
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-50757] BCL2 [mitochondrial outer membrane] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-BTA-879209] Bcl-2/Bcl-X(L) [mitochondrial outer membrane] - Bos taurus
name	BCL2 BCL2 F6R2C4
referenceEntity	[ReferenceGeneProduct:uniprot:F6R2C4] UniProt:F6R2C4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-50757
startCoordinate	1

(input)	[Reaction:R-BTA-9692376] BCL2 binds BCL2 antagonists [Reaction:R-BTA-508163] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 [Reaction:R-BTA-114352] Sequestration of tBID by BCL-2
(hasComponent)	[Complex:R-BTA-9692353] BCL2:BCL2 antagonists [mitochondrial outer membrane] [Complex:R-BTA-508158] Bcl2:BH3-only protein complex [mitochondrial outer membrane] [Complex:R-BTA-114268] BAD:BCL-2 [mitochondrial outer membrane] [Complex:R-BTA-114339] tBID:BCL-2 [mitochondrial outer membrane]
(hasMember)	[DefinedSet:R-BTA-879209] Bcl-2/Bcl-X(L) [mitochondrial outer membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-50757] BCL2 [mitochondrial outer membrane]

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