Reactome | TAB1:TAB2,TAB3:TAK1 [cytosol]

Schema > Complex > Entries

TAB1:TAB2,TAB3:TAK1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-5357837] TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] - Homo sapiens [Complex:R-HSA-2685689] DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] - Homo sapiens [Complex:R-HSA-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Homo sapiens [Complex:R-HSA-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5357860] TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex - Homo sapiens [Reaction:R-HSA-5607759] TRIKA2 binds K63polyUb-TRAF6 oligomer - Homo sapiens [Reaction:R-HSA-936947] Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex - Homo sapiens [Reaction:R-HSA-936947] Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex - Homo sapiens [Reaction:R-HSA-177690] Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex - Homo sapiens [Reaction:R-HSA-177690] Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex - Homo sapiens [Reaction:R-HSA-9645406] ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) - Homo sapiens [Reaction:R-HSA-9645406] ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) - Homo sapiens [Reaction:R-HSA-2730861] Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 - Homo sapiens
created	[InstanceEdit:450323] Shamovsky, V, 2009-12-16
dbId	450277
displayName	TAB1:TAB2,TAB3:TAK1 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-HSA-168156] MAP3K7 [cytosol] [EntityWithAccessionedSequence:R-HSA-167923] TAB1 [cytosol] [DefinedSet:R-HSA-446874] TAB2,TAB3 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-446878] TAK1 complex [cytosol] - Mus musculus [Complex:R-RNO-446878] TAK1 complex [cytosol] - Rattus norvegicus [Complex:R-CFA-446878] TAK1 complex [cytosol] - Canis familiaris [Complex:R-BTA-446878] TAK1 complex [cytosol] - Bos taurus [Complex:R-SSC-446878] TAK1 complex [cytosol] - Sus scrofa [Complex:R-XTR-446878] TAK1 complex [cytosol] - Xenopus tropicalis [Complex:R-GGA-446878] TAK1 complex [cytosol] - Gallus gallus
isChimeric	false
maxDepth	3
modified	[InstanceEdit:8947974] Jupe, Steve, 2016-11-08
name	TAB1:TAB2,TAB3:TAK1 TRIKA2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-450277
updateTrackers	[UpdateTracker:9876248] Update Tracker - [Complex:450277] TAB1:TAB2,TAB3:TAK1 [cytosol] - v44:[modifyName] [UpdateTracker:9895048] Update Tracker - [Complex:450277] TAB1:TAB2,TAB3:TAK1 [cytosol] - v59:[add_removeHasComponent] [UpdateTracker:9869836] Update Tracker - [Complex:450277] TAB1:TAB2,TAB3:TAK1 [cytosol] - v35:[add_removeHasComponent, modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9876248] Update Tracker - [Complex:450277] TAB1:TAB2,TAB3:TAK1 [cytosol] - v44:[modifyName] [UpdateTracker:9895048] Update Tracker - [Complex:450277] TAB1:TAB2,TAB3:TAK1 [cytosol] - v59:[add_removeHasComponent] [UpdateTracker:9869836] Update Tracker - [Complex:450277] TAB1:TAB2,TAB3:TAK1 [cytosol] - v35:[add_removeHasComponent, modifyName]
(hasComponent)	[Complex:R-HSA-5357837] TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] [Complex:R-HSA-5607672] p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] [Complex:R-HSA-2685689] DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] [Complex:R-HSA-2685709] DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:activated TAK1 complex [plasma membrane] [Complex:R-HSA-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]
(input)	[Reaction:R-HSA-5357860] TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex [Reaction:R-HSA-5607759] TRIKA2 binds K63polyUb-TRAF6 oligomer [Reaction:R-HSA-2730861] Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 [Reaction:R-HSA-936947] Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex [Reaction:R-HSA-177690] Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex [Reaction:R-HSA-9645406] ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1)

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