Reactome | activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]

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activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] Show undefined attributes

catalystActivities	[CatalystActivity:936943] protein serine/threonine kinase activity of activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]
compartment	[Compartment:74700] endosome membrane
consumedByEvent	[Reaction:R-HSA-936951] Activation of TAK1 complex bound to activated TLR4 complex - Homo sapiens
created	[InstanceEdit:936971] Shamovsky, V, 2010-08-25
dbId	936954
displayName	activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]
hasComponent	[Complex:R-HSA-936965] K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] 2 × [Polymer:R-HSA-450152] K63polyUb [cytosol] 2 × [Complex:R-HSA-450277] TAB1:TAB2,TAB3:TAK1 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:171907] endosome lumen
inferredTo	[Complex:R-MMU-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Mus musculus [Complex:R-RNO-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Rattus norvegicus [Complex:R-CFA-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Canis familiaris [Complex:R-BTA-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Bos taurus [Complex:R-SSC-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Sus scrofa [Complex:R-GGA-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:433849] Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation
maxDepth	7
modified	[InstanceEdit:9014358] Shamovsky, Veronica, 2017-07-28
name	activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex
producedByEvent	[Reaction:R-HSA-936947] Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-936954
updateTrackers	[UpdateTracker:9897589] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v62:[modifyName, removeLiteratureReference, updateContainedComponent] [UpdateTracker:9870982] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9873122] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v42:[addLiteratureReference, modifyName, updateContainedComponent] [UpdateTracker:9876639] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v44:[updateContainedComponent] [UpdateTracker:9872106] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v41:[add_removeCompartment, add_removeHasComponent, modifyName, removeSpecies, updateContainedComponent] [UpdateTracker:9870061] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v37:[updateContainedComponent] [UpdateTracker:9891322] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v52:[updateContainedComponent] [UpdateTracker:9895766] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v59:[updateContainedComponent] [UpdateTracker:9893011] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v54:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9897589] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v62:[modifyName, removeLiteratureReference, updateContainedComponent] [UpdateTracker:9870982] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9873122] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v42:[addLiteratureReference, modifyName, updateContainedComponent] [UpdateTracker:9876639] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v44:[updateContainedComponent] [UpdateTracker:9872106] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v41:[add_removeCompartment, add_removeHasComponent, modifyName, removeSpecies, updateContainedComponent] [UpdateTracker:9870061] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v37:[updateContainedComponent] [UpdateTracker:9891322] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v52:[updateContainedComponent] [UpdateTracker:9895766] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v59:[updateContainedComponent] [UpdateTracker:9893011] Update Tracker - [Complex:936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - v54:[updateContainedComponent]
(output)	[Reaction:R-HSA-936947] Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex
(input)	[Reaction:R-HSA-936951] Activation of TAK1 complex bound to activated TLR4 complex
(physicalEntity)	[CatalystActivity:936943] protein serine/threonine kinase activity of activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]

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