Reactome | PAK1,2,3 [cytosol]

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PAK1,2,3 [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:376139] protein serine/threonine kinase activity of PAK1,2,3 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-5357487] p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-430183] NCK binds PAK - Homo sapiens
created	[InstanceEdit:390764] Garapati, P V, 2009-02-10 10:38:35
dbId	390765
displayName	PAK1,2,3 [cytosol]
hasMember	[EntityWithAccessionedSequence:R-HSA-162629] PAK1 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-211604] PAK2 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-428457] PAK3 [cytosol] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-390765] PAK1,2,3 [cytosol] - Mus musculus [DefinedSet:R-RNO-390765] PAK1,2,3 [cytosol] - Rattus norvegicus [DefinedSet:R-CFA-390765] PAK1,2,3 [cytosol] - Canis familiaris [DefinedSet:R-BTA-390765] PAK1,2,3 [cytosol] - Bos taurus [DefinedSet:R-SSC-390765] PAK1,2,3 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-211604] PAK2 [cytosol] - Danio rerio [DefinedSet:R-XTR-390765] PAK1,2,3 [cytosol] - Xenopus tropicalis [DefinedSet:R-GGA-390765] PAK1,2,3 [cytosol] - Gallus gallus [DefinedSet:R-DME-390765] PAK1,2,3 [cytosol] - Drosophila melanogaster [DefinedSet:R-CEL-390765] PAK1,2,3 [cytosol] - Caenorhabditis elegans [DefinedSet:R-DDI-390765] PAK1,2,3 [cytosol] - Dictyostelium discoideum [DefinedSet:R-SPO-390765] PAK1,2,3 [cytosol] - Schizosaccharomyces pombe [DefinedSet:R-SCE-390765] PAK1,2,3 [cytosol] - Saccharomyces cerevisiae
maxDepth	2
modified	[InstanceEdit:5627778] Orlic-Milacic, Marija, 2014-10-20
name	PAK1,2,3
producedByEvent	[Reaction:R-HSA-389788] Activation of PAKs by RAC1 and CDC42 - Homo sapiens [Reaction:R-HSA-399930] Activation of PAK by Rac1 - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-390765
updateTrackers	[UpdateTracker:9889750] Update Tracker - [DefinedSet:390765] PAK1,2,3 [cytosol] - v49:[addHasMember, modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9889750] Update Tracker - [DefinedSet:390765] PAK1,2,3 [cytosol] - v49:[addHasMember, modifyName]
(physicalEntity)	[CatalystActivity:376139] protein serine/threonine kinase activity of PAK1,2,3 [cytosol]
(hasComponent)	[Complex:R-HSA-5357487] p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] [Complex:R-HSA-389782] PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] [Complex:R-HSA-430189] p-SLP-76:NCK:PAK [cytosol] [Complex:R-HSA-399876] Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane]
(output)	[Reaction:R-HSA-389788] Activation of PAKs by RAC1 and CDC42 [Reaction:R-HSA-399930] Activation of PAK by Rac1
(input)	[Reaction:R-HSA-430183] NCK binds PAK
(activeUnit)	[CatalystActivity:399940] protein serine/threonine kinase activity of Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane]

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